ChemicalBook > CAS DataBase List > 1-Ethylpiperazine

1-Ethylpiperazine

Product Name
1-Ethylpiperazine
CAS No.
5308-25-8
Chemical Name
1-Ethylpiperazine
Synonyms
N-ETHYLPIPERAZINE;NEPRZ;1-Ethylperazine;N-Ethylpiperazin;AKOS BBS-00003610;1-ETHYLPIPERAZINE;ETHYLPIPERAZINE-N;1-ethyl-piperazin;1-ethvlpiperazine;TIMTEC-BB SBB006719
CBNumber
CB6384137
Molecular Formula
C6H14N2
Formula Weight
114.19
MOL File
5308-25-8.mol
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1-Ethylpiperazine Property

Melting point:
-60 °C
Boiling point:
157 °C(lit.)
Density 
0.899 g/mL at 25 °C(lit.)
vapor pressure 
2.48hPa at 20℃
refractive index 
n20/D 1.469(lit.)
Flash point:
110 °F
storage temp. 
2-8°C
solubility 
soluble
form 
Liquid
pka
9.27±0.10(Predicted)
Specific Gravity
0.899
color 
Clear colorless to yellow
Water Solubility 
soluble
Sensitive 
Air Sensitive
BRN 
102971
InChIKey
WGCYRFWNGRMRJA-UHFFFAOYSA-N
LogP
-0.1 at 20℃
CAS DataBase Reference
5308-25-8(CAS DataBase Reference)
NIST Chemistry Reference
N-ethylpiperazine(5308-25-8)
EPA Substance Registry System
Piperazine, 1-ethyl- (5308-25-8)
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Safety

Hazard Codes 
Xi,Hazard
Risk Statements 
36/37/38-10
Safety Statements 
26-36
RIDADR 
UN 1993 3/PG 3
WGK Germany 
1
RTECS 
TM0815500
F 
10-34
HazardClass 
3
PackingGroup 
III
HS Code 
29335995
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
415308
Product name
1-Ethylpiperazine
Purity
98%
Packaging
50ml
Price
$48
Updated
2024/03/01
Sigma-Aldrich
Product number
1266802
Product name
1-Ethylpiperazine
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
0.5ml
Price
$1720
Updated
2024/03/01
TCI Chemical
Product number
E0355
Product name
1-Ethylpiperazine
Purity
>98.0%(GC)(T)
Packaging
25mL
Price
$21
Updated
2024/03/01
TCI Chemical
Product number
E0355
Product name
1-Ethylpiperazine
Purity
>98.0%(GC)(T)
Packaging
100mL
Price
$46
Updated
2024/03/01
Alfa Aesar
Product number
L15539
Product name
1-Ethylpiperazine, 98%
Packaging
100g
Price
$45.65
Updated
2024/03/01
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1-Ethylpiperazine Chemical Properties,Usage,Production

Chemical Properties

clear colorless to yellow liquid

Uses

1-Ethylpiperazine is used in the synthesis of 2-(2-methoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1H-benzo[d]imidazole hydrochloride and 2-(5-((4-ethylpiperazin-1-yl)sulfonyl)-2-methoxyphenyl)-1H-benzo[d]imidazole hydrochloride. It is also employed as an intermediate in veterinary medicine, especially in the production of ciproflmoxacin ethyl. Further, it serves as a precursor to prepare dyes.

Uses

1-Ethylpiperazine may be used in the preparation of 2-(2-methoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1H-benzo[d]imidazole hydrochloride and 2-(5-((4-ethylpiperazin-1-yl)sulfonyl)-2-methoxyphenyl)-1H-benzo[d]imidazole hydrochloride.

Synthesis Reference(s)

The Journal of Organic Chemistry, 22, p. 713, 1957 DOI: 10.1021/jo01357a621

Flammability and Explosibility

Flammable

1-Ethylpiperazine Preparation Products And Raw materials

Raw materials

Ethanol CHLOROETHANE Piperazine Sodium iodide Hydrochloric acid Sodium hydroxide

Preparation Products

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1-Ethylpiperazine Suppliers

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View Lastest Price from 1-Ethylpiperazine manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
1-Ethylpiperazine 5308-25-8
Price
US $45.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/week
Release date
2024-05-31
Hebei Weibang Biotechnology Co., Ltd
Product
1-Ethylpiperazine 5308-25-8
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-22
Hebei Chuanghai Biotechnology Co,.LTD
Product
1-Ethylpiperazine 5308-25-8
Price
US $10.00/KG
Min. Order
1KG
Purity
95%
Supply Ability
10 ton
Release date
2024-08-20

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