4-IODOTETRAHYDRO-2H-PYRAN

Product Name: 4-IODOTETRAHYDRO-2H-PYRAN
CAS No.: 25637-18-7
Chemical Name: 4-IODOTETRAHYDRO-2H-PYRAN
Synonyms: 4-iodooxane;4-IODO-TETRAHYDRO-PYRAN;4-IODOTETRAHYDRO-2H-PYRAN;Tetrahydro-4-iodo-2H-pyran;4-Iodotetrahydro-2H-pyrane;2H-Pyran, tetrahydro-4-iodo-;4-Iodotetrahydro-2H-pyran 97%;25637-184-IODOTETRAHYDRO-2H-PYRAN-7;4-Iodotetrahydro-2H-pyran,97%,stabilized with Na2O3S2
CBNumber: CB6403559
Molecular Formula: C5H9IO
Formula Weight: 212.03
MOL File: 25637-18-7.mol

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4-IODOTETRAHYDRO-2H-PYRAN Property

Boiling point:: 79 °C
Density: 1.77±0.1 g/cm3(Predicted)
refractive index: 1.5471
storage temp.: 2-8°C(protect from light)
form: liquid
color: Clear, colourless
InChI: InChI=1S/C5H9IO/c6-5-1-3-7-4-2-5/h5H,1-4H2
InChIKey: JTRNQTFTRDPITG-UHFFFAOYSA-N
SMILES: C1OCCC(I)C1

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Safety

Hazard Codes: Xi
Risk Statements: 36-36/37/38
Safety Statements: 26-36/37/39
Hazard Note: Irritant
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AstaTech

Product number: 25900
Product name: 4-IODOTETRAHYDROPYRAN
Purity: 97%
Packaging: 5G
Price: $66
Updated: 2026/04/30

AstaTech

Product number: 25900
Product name: 4-IODOTETRAHYDROPYRAN
Purity: 97%
Packaging: 25G
Price: $227
Updated: 2026/04/30

AstaTech

Product number: 25900
Product name: 4-IODOTETRAHYDROPYRAN
Purity: 97%
Packaging: 50G
Price: $386
Updated: 2026/04/30

Chem-Impex

Product number: 19007
Product name: 4-Iodotetrahydro-2H-pyran
Purity: ≥99%(HPLC)
Packaging: 1G
Price: $36.65
Updated: 2026/05/19

Chem-Impex

Product number: 19007
Product name: 4-Iodotetrahydro-2H-pyran
Purity: ≥99%(HPLC)
Packaging: 5G
Price: $121.18
Updated: 2026/05/19

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4-IODOTETRAHYDRO-2H-PYRAN Chemical Properties,Usage,Production

Synthesis

2081-44-9

25637-18-7

GENERAL STEPS: Tetrahydro-2H-pyran-4-ol (2.0 g, 19.58 mmol), imidazole (1.600 g, 23.50 mmol), triphenylphosphine (5.39 g, 20.56 mmol) and tetrahydrofuran (39.2 mL) were added to a round bottom flask (RBF) and the mixture was cooled to 0 °C. A solution of iodine (5.96 g, 23.50 mmol) in tetrahydrofuran (39.2 mL) was slowly added dropwise with stirring. After dropwise addition, the reaction mixture was gradually warmed to room temperature and stirring was continued overnight. After completion of the reaction, the reaction mixture was diluted with ethyl acetate and washed with deionized water. The aqueous layer was back-extracted with ethyl acetate, all organic layers were combined, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. Purification of the crude product by column chromatography (using a RediSep Gold 80g silica gel column eluting with a 0-50% ethyl acetate/heptane gradient) afforded 4-iodotetrahydro-2H-pyran (2.67 g, 12.59 mmol, 64.3% yield) as a clarified light yellow oil.

References

[1] Journal of the American Chemical Society, 2017, vol. 139, # 24, p. 8110 - 8113
[2] Patent: US9212182, 2015, B2. Location in patent: Page/Page column 79
[3] Organic Letters, 2013, vol. 15, # 7, p. 1658 - 1661
[4] Patent: WO2018/106636, 2018, A1. Location in patent: Paragraph 00281
[5] Journal of the Chemical Society, 1952, p. 910,913

4-IODOTETRAHYDRO-2H-PYRAN Preparation Products And Raw materials

Raw materials

Preparation Products

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4-IODOTETRAHYDRO-2H-PYRAN Suppliers

Austria 1 Belgium 1 China 146 France 1 Germany 1 India 5 United Kingdom 1 United States 15 Global 171

BTC Pharmaceutical CO. Ltd

Tel: +86-15716293042;0513-68015397;15716293042 18862997610;18862996710
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Country: China
ProdList: 732
Advantage: 55

Shanghai alkynechem Co., Ltd.

Tel: 086-021-15821262312 15821262312
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Energy Chemical

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Email: sales8178@energy-chemical.com
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Tetranov Biopharm

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Country: China
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Accela ChemBio Co.,Ltd.

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Fax: 021-50795055
Email: marketing@accelachem.com
Country: China
ProdList: 10977
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Shanghai Hanhong Scientific Co.,Ltd.

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China DongFan Chemical Co.,LTD

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Shanghai Ennopharm Co., Ltd.

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Shanghai AmasPharm Co., Ltd.

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Changzhou Wanyao Biotechnology Co., Ltd.

Tel: 0519-89185693 15312551983
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Email: 2410037592@qq.com
Country: China
ProdList: 263
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View Lastest Price from 4-IODOTETRAHYDRO-2H-PYRAN manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 4-iodotetrahydro-2H-pyran 25637-18-7
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-22

Henan Aochuang Chemical Co.,Ltd.

Product: 4-IODOTETRAHYDRO-2H-PYRAN 25637-18-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-26

Career Henan Chemical Co

Product: 4-Iodotetrahydro-2H-pyran 25637-18-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 500kg
Release date: 2018-08-16

25637-18-7, 4-IODOTETRAHYDRO-2H-PYRANRelated Search:

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4-IODOTETRAHYDRO-2H-PYRAN

4-IODO-TETRAHYDRO-PYRAN

4-Iodotetrahydro-2H-pyrane

4-Iodotetrahydro-2H-pyran 97%

2H-Pyran, tetrahydro-4-iodo-

4-iodooxane

Tetrahydro-4-iodo-2H-pyran

25637-184-IODOTETRAHYDRO-2H-PYRAN-7

4-Iodotetrahydro-2H-pyran,97%,stabilized with Na2O3S2

25637-18-7