HUMAN IL-1ALPHA

Description Source Background

Product Name: HUMAN IL-1ALPHA
CAS No.: 97599-22-9
Chemical Name: HUMAN IL-1ALPHA
Synonyms: HUMAN EP;HUMAN LAF;HUMAN LEM;HUMAN MCF;HIL-1ALPHA;HUMAN IL-1A;HUMAN IL-1ALPHA;IL-1 ALPHA, HUMAN;REC IL-1A (HUMAN);REC IL-1ALPHA (HUMAN)
CBNumber: CB6432102
Formula Weight: 0
MOL File: Mol file

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HUMAN IL-1ALPHA Property

storage temp.: -15°C
form: lyophilized
biological source: human

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26

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Hazard and Precautionary Statements (GHS)

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HUMAN IL-1ALPHA Chemical Properties,Usage,Production

Biological Activity

IL-1α (interleukin) and IL-1β bind with IL-1 receptor and function as proinflammatory cytokines, whereas IL-1Rα competes to bind with IL-1R but is not proinflammatory. IL-1α can function as an intracrine molecule or as a transcription factor. IL-1 plays a major role in ischemic brain damage, as the inactivation of both IL-1α and IL-1β lead to significant suppression in brain injury. However, inactivation of only IL-1α does not have much influence on overall damage due to some compensatory modifications in the IL-1 system. A hospital-based case-control study showed th at rs3783553 variant in this gene is linked with reduced risk of breast cancer. Tumor cell production of IL-1α helps their transmigration across the endothelium, and the expression of IL-1α is linked with distant metastasis in patients with head and neck squamous cell carcinoma.

Description

Interleukin-1 alpha Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 159 amino acids and having a molecular mass of 18022 Dalton.
The IL-1A is purified by proprietary chromatographic techniques.

Source

Escherichia Coli

Background

IL-1 alpha is produced by activated macrophages, stimulates thymocyte proliferation by inducing il-2 release, b-cell maturation and proliferation, and fibroblast growth factor activity. IL1A proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin from synovial cells.

HUMAN IL-1ALPHA Preparation Products And Raw materials

Raw materials

Preparation Products

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HUMAN IL-1ALPHA Suppliers

China 39 Germany 1 Japan 2 United Kingdom 1 United States 13 Global 56

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
Advantage: 58

Wuhan Chemstan Biotechnology Co., Ltd.

Tel: 027-65317797 15926423062
Fax: QQ：422450190
Email: 422450190@qq.com
Country: China
ProdList: 10308
Advantage: 58

Wuhan Peptide Core Biotechnology Co., Ltd

Tel: 027-65317797 13667154760
Email: 1096814016@qq.com
Country: China
ProdList: 10711
Advantage: 58

Merck KGaA

Tel: 21-20338288
Email: ordercn@merckgroup.com
Country: China
ProdList: 6394
Advantage: 58

Wuhan Fine Biotech Co Ltd

Tel: 13047170542
Email: marketing@fn-test.com
Country: China
ProdList: 6600
Advantage: 58

Antibodies com

Tel: 65-6980-8108 65698081
Email: info@probioscience.org
Country: China
ProdList: 6014
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Adooq Bioscience LLC

Tel: 400-025-6535
Email: sales@adooq.cn
Country: China
ProdList: 6215
Advantage: 58

ProSpec Tany TechnoGene Ltd

Tel: 972-8947-1175
Email: info@prospecbio.com
Country: China
ProdList: 6874
Advantage: 58

97599-22-9, HUMAN IL-1ALPHARelated Search:

Benzyl isocyanide COBALT(II) ACETYLACETONATE SALCOMINE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) METHYL ISOCYANOACETATE Aluminum acetylacetonate PHENYLSELENOL 2,4-PENTANEDIONE, SILVER DERIVATIVE Cupric acetylacetonate Ethyl isocyanoacetate Ferric acetylacetonate TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) TERT-BUTYL ISOCYANIDE N-BUTYLISOCYANIDE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Tris(2,4-pentanedionato)chroMiuM(III) 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Tosylmethyl isocyanide

Lymphocyte-activating factor (LAF)

REC IL-1A (HUMAN)

REC IL-1ALPHA (HUMAN)

REC INTERLEUKIN-1A (HUMAN)

REC INTERLEUKIN-1ALPHA (HUMAN)

RECOMBINANT HUMAN IL-1A

INTERLEUKIN-1ALPHA, HUMAN

INTERLEUKIN-1ALPHA, HUMAN, RECOMBINANT, E COLI

IL-1 ALPHA, HUMAN

HUMAN EP

HUMAN ENDOGENOUS PYROGEN

HUMAN IL-1A

HUMAN IL-1ALPHA

HUMAN HEMATOPOIETIN-1

HUMAN LYMPHOCYTE-ACTIVATING FACTOR

HUMAN LEUKOCYTE ENDOGENOUS MEDIATOR

HUMAN LAF

HUMAN LEM

HUMAN INTERLEUKIN-1 ALPHA

HUMAN MCF

HUMAN MONONUCLEAR CELL FACTOR

HIL-1ALPHA

INTERLEUKIN-1ALPHA (IL-1ALPHA), HUMAN, RECOMBINANT

Endogenous Pyrogen (EP)

97599-22-9

Human