HUMAN IL-1ALPHA

Description Source Background

Product Name: HUMAN IL-1ALPHA
CAS No.: 97599-22-9
Chemical Name: HUMAN IL-1ALPHA
Synonyms: HUMAN EP;HUMAN LAF;HUMAN LEM;HUMAN MCF;HIL-1ALPHA;HUMAN IL-1A;HUMAN IL-1ALPHA;IL-1 ALPHA, HUMAN;REC IL-1A (HUMAN);REC IL-1ALPHA (HUMAN)
CBNumber: CB6432102
Formula Weight: 0
MOL File: Mol file

More

Less

HUMAN IL-1ALPHA Property

storage temp.: -15°C
form: lyophilized
biological source: human

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

HUMAN IL-1ALPHA Chemical Properties,Usage,Production

Biological Activity

IL-1α (interleukin) and IL-1β bind with IL-1 receptor and function as proinflammatory cytokines, whereas IL-1Rα competes to bind with IL-1R but is not proinflammatory. IL-1α can function as an intracrine molecule or as a transcription factor. IL-1 plays a major role in ischemic brain damage, as the inactivation of both IL-1α and IL-1β lead to significant suppression in brain injury. However, inactivation of only IL-1α does not have much influence on overall damage due to some compensatory modifications in the IL-1 system. A hospital-based case-control study showed th at rs3783553 variant in this gene is linked with reduced risk of breast cancer. Tumor cell production of IL-1α helps their transmigration across the endothelium, and the expression of IL-1α is linked with distant metastasis in patients with head and neck squamous cell carcinoma.

Description

Interleukin-1 alpha Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 159 amino acids and having a molecular mass of 18022 Dalton.
The IL-1A is purified by proprietary chromatographic techniques.

Source

Escherichia Coli

Background

IL-1 alpha is produced by activated macrophages, stimulates thymocyte proliferation by inducing il-2 release, b-cell maturation and proliferation, and fibroblast growth factor activity. IL1A proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin from synovial cells.

HUMAN IL-1ALPHA Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

HUMAN IL-1ALPHA Suppliers

China 39 Germany 1 Japan 2 United Kingdom 1 United States 13 Global 56

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

Cell Sciences, Inc.

Tel: --
Fax: --
Country: United States
ProdList: 1065
Advantage: 76

Chem-Impex International, Inc.

Tel: --
Fax: --
Country: United States
ProdList: 6730
Advantage: 64

Upstate

Tel: --
Fax: --
Email: info@upstate.com
Country: United States
ProdList: 876
Advantage: 76

Pierce Biotechnology, Inc.

Tel: --
Fax: --
Email: cs@piercenet.com
Country: United States
ProdList: 966
Advantage: 82

Chemicon Internatinal, Inc.

Tel: --
Fax: --
Email: custserv@chemicon.com
Country: United States
ProdList: 4175
Advantage: 65

R & D Systems

Tel: --
Fax: --
Email: info@rndsystems.com
Country: United States
ProdList: 2195
Advantage: 82

Roche Applied Science

Tel: --
Fax: --
Email: biochemts.us@roche.com
Country: United States
ProdList: 696
Advantage: 85

BioSource International, Inc.

Tel: --
Fax: --
Email: sales.desk@biosource.com
Country: United States
ProdList: 1011
Advantage: 63

PeproTech Inc.

Tel: --
Fax: --
Email: info@peprotech.com
Country: United States
ProdList: 644
Advantage: 75

EMD Biosciences, Inc.

Tel: --
Fax: --
Email: technical@calbiochem.com
Country: United States
ProdList: 6529
Advantage: 66

BD Biosciences

Tel: --
Fax: --
Country: United States
ProdList: 5013
Advantage: 82

MP Biomedicals, Inc.

Tel: --
Fax: --
Country: United States
ProdList: 6561
Advantage: 81

97599-22-9, HUMAN IL-1ALPHARelated Search:

Benzyl isocyanide COBALT(II) ACETYLACETONATE SALCOMINE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) METHYL ISOCYANOACETATE Aluminum acetylacetonate PHENYLSELENOL 2,4-PENTANEDIONE, SILVER DERIVATIVE Cupric acetylacetonate Ethyl isocyanoacetate Ferric acetylacetonate TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) TERT-BUTYL ISOCYANIDE N-BUTYLISOCYANIDE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Tris(2,4-pentanedionato)chroMiuM(III) 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Tosylmethyl isocyanide

Lymphocyte-activating factor (LAF)

REC IL-1A (HUMAN)

REC IL-1ALPHA (HUMAN)

REC INTERLEUKIN-1A (HUMAN)

REC INTERLEUKIN-1ALPHA (HUMAN)

RECOMBINANT HUMAN IL-1A

INTERLEUKIN-1ALPHA, HUMAN

INTERLEUKIN-1ALPHA, HUMAN, RECOMBINANT, E COLI

IL-1 ALPHA, HUMAN

HUMAN EP

HUMAN ENDOGENOUS PYROGEN

HUMAN IL-1A

HUMAN IL-1ALPHA

HUMAN HEMATOPOIETIN-1

HUMAN LYMPHOCYTE-ACTIVATING FACTOR

HUMAN LEUKOCYTE ENDOGENOUS MEDIATOR

HUMAN LAF

HUMAN LEM

HUMAN INTERLEUKIN-1 ALPHA

HUMAN MCF

HUMAN MONONUCLEAR CELL FACTOR

HIL-1ALPHA

INTERLEUKIN-1ALPHA (IL-1ALPHA), HUMAN, RECOMBINANT

Endogenous Pyrogen (EP)

97599-22-9

Human