Temocaprilat

ChemicalBook > CAS DataBase List > Temocaprilat

Product Name: Temocaprilat
CAS No.: 110221-53-9
Chemical Name: Temocaprilat
Synonyms: Temocaprilate;RS-5139;Temocaprilat;[3H]-Temocaprilat;Temocapril Diacid;Temocapril Impurity 1;TEMOCAPRILAT(FORR&DONLY);Temocaprilat, 10 mM in DMSO;[[[2S,6R]-6-[[(S)-1-Carboxy-3-phenylpropyl]amino]hexahydro-5-oxo-2-(2-thienyl)-1,4-thiazepin]-4-yl]acetic acid;(2S,6R)-6-[[(1S)-1-Carboxy-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-1,4-thiazepine-4(5H)-acetic Acid
CBNumber: CB6501004
Molecular Formula: C21H24N2O5S2
Formula Weight: 448.56
MOL File: 110221-53-9.mol

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Temocaprilat Property

Melting point:: >2300C (dec)
alpha: 25D +63.4° (c = 1 in DMF)
Boiling point:: 743.6±60.0 °C(Predicted)
Density: 1.41±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 2.09±0.10(Predicted)
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22169
Product name: Temocaprilat
Packaging: 500μg
Price: $121
Updated: 2024/03/01

Cayman Chemical

Product number: 22169
Product name: Temocaprilat
Packaging: 1mg
Price: $218
Updated: 2024/03/01

Cayman Chemical

Product number: 22169
Product name: Temocaprilat
Packaging: 5mg
Price: $722
Updated: 2024/03/01

TRC

Product number: T017305
Product name: Temocaprilat
Packaging: 1g
Price: $1015
Updated: 2021/12/16

AK Scientific

Product number: O437
Product name: Temocaprilat
Packaging: 1g
Price: $1366
Updated: 2021/12/16

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Temocaprilat Chemical Properties,Usage,Production

Description

Temocaprilat is an inhibitor of angiotensin-converting enzyme (ACE; IC₅₀ = 3.6 nM for rabbit lung ACE). It inhibits contraction of isolated rat aorta induced by angiotensin I with an IC₅₀ value of 7.6 nM. Temocaprilat (1-30 μg/kg, i.v.) inhibits angiotensin I-induced pressor responses in anesthetized rats in a dose-dependent manner.

Chemical Properties

White to Off-White Solid

Uses

Antihypertensive.

Definition

ChEBI: Temocaprilat is a non-proteinogenic alpha-amino acid.

Temocaprilat Preparation Products And Raw materials

Raw materials

Preparation Products

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Temocaprilat Suppliers

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110221-53-9, TemocaprilatRelated Search:

2-Aminophenol Glycine Thifensulfuron Cephalothin sodium Tris(hydroxymethyl)aminomethane 1,1'-Carbonyldiimidazole 6-Aminocaproic acid ALTRENOGEST Tetrahydrothiophene Temocapril hydrochloride (2S,6R)-6-Amino-2-(2-thienyl)-1,4-thiazepan-5-one 2-Thienylmethanethiol Carbonyl iron powder 2-[(2S)-6-[[(1S)-1-Ethoxycarbonyl-3-phenyl-propyl]amino]-5-oxo-2-thiophen-2-yl-1,4-thiazepan-4-yl]acetic acid L-β-Homophenylalanine, HPLC 98% TEMOCAPRIL-D5 1-(2'-THIENYL)ETHYLMERCAPTAN Temocaprilat

[3H]-Temocaprilat

RS-5139

TEMOCAPRILAT(FORR&DONLY)

(+)-[(2S,6R)-6-[[(S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-5-oxo-2-(2-thienyl)perhydro-1,4-thiazepin-4-yl]acetic acid

[[[2S,6R]-6-[[(S)-1-Carboxy-3-phenylpropyl]amino]hexahydro-5-oxo-2-(2-thienyl)-1,4-thiazepin]-4-yl]acetic acid

(2S,6R)-6-[[(1S)-1-Carboxy-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-1,4-thiazepine-4(5H)-acetic Acid

Temocapril Diacid

Temocaprilate

Temocaprilat

1,4-Thiazepine-4(5H)-acetic acid, 6-[[(1S)-1-carboxy-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-, (2S,6R)-

Temocapril Impurity 1

Temocaprilat, 10 mM in DMSO

110221-53-9

C21H24N2O5S2

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