ChemicalBook > CAS DataBase List > 4,6-Dichloro-5-methylpyrimidine

4,6-Dichloro-5-methylpyrimidine

Application

Product Name: 4,6-Dichloro-5-methylpyrimidine
CAS No.: 4316-97-6
Chemical Name: 4,6-Dichloro-5-methylpyrimidine
Synonyms: 4,6-DICHLORO-5-METHYLPYRIMIDIN;4,6-DICHLORO-5-METHYLPYRIMIDINE;Pyrimidine, 4,6-dichloro-5-methy;4,6-Dichloro-5-methyl-1,3-diazine;4,6-Dichloro-5-methylpyrimidine>Pyrimidine, 4,6-dichloro-5-methyl-;4,6-Dichloro-5-MethylpyriMidine, 97+%;4-chloro-6-methoxy-5-methylpyrimidine;4,6-Dichloro-5-methylpyrimidine ISO 9001：2015 REACH
CBNumber: CB6747309
Molecular Formula: C5H4Cl2N2
Formula Weight: 163
MOL File: 4316-97-6.mol

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4,6-Dichloro-5-methylpyrimidine Property

Melting point:: 56-60 °C (lit.)
storage temp.: Inert atmosphere,2-8°C
solubility: soluble in Methanol
form: powder to crystal
color: White to Light yellow to Light orange
CAS DataBase Reference: 4316-97-6(CAS DataBase Reference)

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Safety

Hazard Codes: C
Risk Statements: 34
Safety Statements: 26-36/37/39-45
RIDADR: UN 3261 8/PG 2
WGK Germany: 3
HazardClass: CORROSIVE
HazardClass: 8
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 595446
Product name: 4,6-Dichloro-5-methylpyrimidine
Purity: 97%
Packaging: 5g
Price: $119
Updated: 2023/06/20

Sigma-Aldrich

Product number: 595446
Product name: 4,6-Dichloro-5-methylpyrimidine
Purity: 97%
Packaging: 1g
Price: $36.1
Updated: 2022/05/15

TCI Chemical

Product number: D4091
Product name: 4,6-Dichloro-5-methylpyrimidine
Purity: >98.0%(GC)
Packaging: 5g
Price: $87
Updated: 2025/07/31

TCI Chemical

Product number: D4091
Product name: 4,6-Dichloro-5-methylpyrimidine
Purity: >98.0%(GC)
Packaging: 25g
Price: $315
Updated: 2025/07/31

TRC

Product number: D435530
Product name: 4,6-Dichloro-5-methylpyrimidine
Packaging: 2g
Price: $115
Updated: 2021/12/16

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4,6-Dichloro-5-methylpyrimidine Chemical Properties,Usage,Production

Application

4,6-Dichloro-5-methylpyrimidine is a heterocyclic organic compound that can be used as an intermediate in organic synthesis.

Chemical Properties

White Solid

Synthesis

18337-63-8

4316-97-6

General procedure for the synthesis of 4,6-dichloro-5-methylpyrimidine from 5-methylpyrimidine-4,6-diol: To a solution of POCl3 (1.9 mol, 174 mL) containing the pyrimidine derivative (0.38 mol, 1 eq.) was slowly added DMF (0.152 mol, 11.7 mL), noting that this process is exothermic. The reaction mixture was heated to reflux and maintained for 3 hours. Upon completion of the reaction, it was cooled to room temperature and the mixture was carefully poured into an ice/water mixture. The precipitated white solid product was collected by filtration, washed well with water and subsequently dried under vacuum to afford 4,6-dichloro-5-methylpyrimidine (1) in 90% yield.

References

[1] Patent: US2006/155129, 2006, A1. Location in patent: Page/Page column 14
[2] Patent: EP1333029, 2003, A1

4,6-Dichloro-5-methylpyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4,6-Dichloro-5-methylpyrimidine manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4,6-Dichloro-5-methylpyrimidine 4316-97-6
Price: US $30.00-10.00/KG
Min. Order: 50KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-24

Henan Aochuang Chemical Co.,Ltd.

Product: 4,6-Dichloro-5-methylpyrimidine 4316-97-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-10-14

Dideu Industries Group Limited

Product: 4,6-Dichloro-5-methylpyrimidine 4316-97-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-06

4316-97-6, 4,6-Dichloro-5-methylpyrimidineRelated Search:

4,6-Dichloro-5-nitropyrimidine Sulfamerazine 4,6-Dichloropyrimidine 4,6-Dichloro-5-fluoropyrimidine 2-Chloro-5-chloromethylpyridine Dichloromethylphenylsilane Dichlorodimethylsilane Pirimiphos-methyl 2,4,6-Trichloro-5-methylpyrimidine 4,6-DICHLORO-2-METHYLTHIO-5-PHENYLPYRIMIDINE 2-AMINO-4,6-DIHYDROXY-5-METHYLPYRIMIDINE 4,6-DICHLORO-2,5-DIPHENYLPYRIMIDINE 2,4-Dichloro-5-methylpyrimidine ,98%,2,4-Dichloro-5-methylpyrimidine**Toxic, Stench**,2,4-DICHLORO-5-METHYLPYRIMIDINE 4,6-DICHLORO-2-METHYLPYRIMIDINE-5-CARBALDEHYDE 5-Bromo-2,4-dichloro-6-methylpyrimidine 5-Amino-4,6-dichloro-2-methylpyrimidine 2-methylsulfonyl-4,6-dichloro-5-methylpyrimidine 4,6-DICHLORO-5-(4-METHOXYBENZYL)PYRIMIDINE

4,6-DICHLORO-5-METHYLPYRIMIDINE

4,6-DICHLORO-5-METHYLPYRIMIDIN

4-chloro-6-methoxy-5-methylpyrimidine

4,6-Dichloro-5-methyl-1,3-diazine

4,6-Dichloro-5-MethylpyriMidine, 97+%

Pyrimidine, 4,6-dichloro-5-methy

Pyrimidine, 4,6-dichloro-5-methyl-

4,6-Dichloro-5-methylpyrimidine&gt

4,6-Dichloro-5-methylpyrimidine ISO 9001：2015 REACH

4316-97-6

Pyrimidines

Halogenated Heterocycles

Heterocyclic Building Blocks

Building Blocks

Heterocycle-Pyrimidine series

PyrimidinesHeterocyclic Building Blocks

Heterocyclic Compounds

Bases & Related Reagents

Heterocycles

Nucleotides

Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Pyrimidines