Etofenamate
- Product Name
- Etofenamate
- CAS No.
- 30544-47-9
- Chemical Name
- Etofenamate
- Synonyms
- ReuMon;TV-485;Rheumon;TVX-485;CS-1431;Bayrogel;Etofenate;Etofenamate;TrauMon Gel;Ethofenamate
- CBNumber
- CB6883241
- Molecular Formula
- C18H18F3NO4
- Formula Weight
- 369.33
- MOL File
- 30544-47-9.mol
Etofenamate Property
- Melting point:
- 25°C
- Boiling point:
- bp.001 130-135°
- Density
- 1.2866 (estimate)
- refractive index
- nD25 1.564
- storage temp.
- Sealed in dry,2-8°C
- solubility
- Practically insoluble in water, miscible with ethanol (96 per cent) and with ethyl acetate.
- pka
- 14.32±0.10(Predicted)
- form
- Oil
- color
- Light yellow to yellow
- Stability:
- Light Sensitive
Safety
- RIDADR
- UN2810 - class 6.1 - PG 3 - EHS - Toxic, liquids, organic, n.o.s., HI: all
- Toxicity
- LD50 in male, female rats (mg/kg): 292, 470 orally; 140, 226 i.v.; 373, 397 i.p.; 643, 568 s.c. (Jacobi)
N-Bromosuccinimide Price
- Product number
- E2499901
- Product name
- Etofenamate for peak identification
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- e2499901
- Price
- $153
- Updated
- 2024/03/01
- Product number
- E2499900
- Product name
- Etofenamate
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- e2499900
- Price
- $150
- Updated
- 2024/03/01
- Product number
- 23674
- Product name
- Etofenamate
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $89
- Updated
- 2024/03/01
- Product number
- 23674
- Product name
- Etofenamate
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $141
- Updated
- 2024/03/01
- Product number
- 23674
- Product name
- Etofenamate
- Purity
- ≥98%
- Packaging
- 250mg
- Price
- $264
- Updated
- 2024/03/01
Etofenamate Chemical Properties,Usage,Production
Chemical Properties
Light Yellow Oil
Originator
Rheumon,Troponwerke,W. Germany,1977
Uses
As a histamine H1 -receptor antagonist, Etofenamate can be used as anti-inflammatory;cyclooxygenase inhibitor and medication used to alleviate joint and muscle pain.
Definition
ChEBI: 2-[3-(trifluoromethyl)anilino]benzoic acid 2-(2-hydroxyethoxy)ethyl ester is a benzoate ester.
Manufacturing Process
16.0 g (0.05 mol) of the potassium salt of N-(3-trifluoromethylphenyl)- anthranilic acid are dissolved in 60 ml of dimethylformamide and heated to 110°C, and 6.2 g (0.05 mol) of 2-(2-chloroethoxy)-ethanol are slowly added. The reaction mixture is then heated to boiling for 2 hours. The precipitated potassium chloride is filtered off and the solvent is removed by evaporation. The residue is separated over a column with 400 g of silica gel (particle size 0.05 to 0.2 mm), using a 1:1 mixture of cyclohexane and glacial acetic acid as eluting agent. 16.0 g of the 2-(2-hydroxyethoxy)-ethyl ester of N-(3- trifluoromethylphenyl)-anthranilic acid are obtained in the form of a pale yellow oil which does not crystallize and cannot be distilled.
Therapeutic Function
Antiinflammatory
Etofenamate Preparation Products And Raw materials
Raw materials
Preparation Products
Etofenamate Suppliers
- Tel
- --
- Fax
- --
- sales@alsachim.com
- Country
- France
- ProdList
- 424
- Advantage
- 0
View Lastest Price from Etofenamate manufacturers
- Product
- Etofenamate 30544-47-9
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-06-15
- Product
- Etofenamate 30544-47-9
- Price
- US $5.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2019-09-03