Etofenamate
- Product Name
- Etofenamate
- CAS No.
- 30544-47-9
- Chemical Name
- Etofenamate
- Synonyms
- ReuMon;TV-485;Rheumon;TVX-485;CS-1431;Bayrogel;Etofenate;Etofenamate;TrauMon Gel;Ethofenamate
- CBNumber
- CB6883241
- Molecular Formula
- C18H18F3NO4
- Formula Weight
- 369.33
- MOL File
- 30544-47-9.mol
Etofenamate Property
- Melting point:
- 25°C
- Boiling point:
- bp.001 130-135°
- Density
- 1.2866 (estimate)
- refractive index
- nD25 1.564
- storage temp.
- Sealed in dry,2-8°C
- solubility
- Practically insoluble in water, miscible with ethanol (96 per cent) and with ethyl acetate.
- pka
- 14.32±0.10(Predicted)
- Stability:
- Light Sensitive
Safety
- RIDADR
- UN2810 - class 6.1 - PG 3 - EHS - Toxic, liquids, organic, n.o.s., HI: all
- Toxicity
- LD50 in male, female rats (mg/kg): 292, 470 orally; 140, 226 i.v.; 373, 397 i.p.; 643, 568 s.c. (Jacobi)
N-Bromosuccinimide Price
- Product number
- E2499901
- Product name
- Etofenamate for peak identification
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- e2499901
- Price
- $153
- Updated
- 2024/03/01
- Product number
- E2499900
- Product name
- Etofenamate
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- e2499900
- Price
- $150
- Updated
- 2024/03/01
- Product number
- 23674
- Product name
- Etofenamate
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $89
- Updated
- 2024/03/01
- Product number
- 23674
- Product name
- Etofenamate
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $141
- Updated
- 2024/03/01
- Product number
- 23674
- Product name
- Etofenamate
- Purity
- ≥98%
- Packaging
- 250mg
- Price
- $264
- Updated
- 2024/03/01
Etofenamate Chemical Properties,Usage,Production
Chemical Properties
Light Yellow Oil
Originator
Rheumon,Troponwerke,W. Germany,1977
Uses
As a histamine H1 -receptor antagonist, Etofenamate can be used as anti-inflammatory;cyclooxygenase inhibitor and medication used to alleviate joint and muscle pain.
Definition
ChEBI: 2-[3-(trifluoromethyl)anilino]benzoic acid 2-(2-hydroxyethoxy)ethyl ester is a benzoate ester.
Manufacturing Process
16.0 g (0.05 mol) of the potassium salt of N-(3-trifluoromethylphenyl)- anthranilic acid are dissolved in 60 ml of dimethylformamide and heated to 110°C, and 6.2 g (0.05 mol) of 2-(2-chloroethoxy)-ethanol are slowly added. The reaction mixture is then heated to boiling for 2 hours. The precipitated potassium chloride is filtered off and the solvent is removed by evaporation. The residue is separated over a column with 400 g of silica gel (particle size 0.05 to 0.2 mm), using a 1:1 mixture of cyclohexane and glacial acetic acid as eluting agent. 16.0 g of the 2-(2-hydroxyethoxy)-ethyl ester of N-(3- trifluoromethylphenyl)-anthranilic acid are obtained in the form of a pale yellow oil which does not crystallize and cannot be distilled.
Therapeutic Function
Antiinflammatory
Etofenamate Preparation Products And Raw materials
Raw materials
Preparation Products
Etofenamate Suppliers
View Lastest Price from Etofenamate manufacturers
- Product
- Etofenamate 30544-47-9
- Price
- US $1.00-1.00/KG
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 50tons
- Release date
- 2020-04-29
- Product
- Etofenamate 30544-47-9
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-06-15
- Product
- Etofenamate 30544-47-9
- Price
- US $5.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2019-09-03