ChemicalBook > CAS DataBase List > n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide

n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide

Product Name
n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide
CAS No.
848133-76-6
Chemical Name
n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide
Synonyms
Neratinib Impurity 40;Neratinib Intermediate 2;N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl);4-chloro-3-cyano-7-ethoxy-6-N-acetylquinoline;N-(4-CHLORO-3-CYANO-7-ETHOXY-6-QUINOLINYL) ACETAMI;4-Chloro-3-cyano-7-ethoxy-6-(acetylamino)quinoline;N-(4-chloro-3-cyano-7-ethoxyquinolin-6-yl)acetaMide;4-Chloro-3-cyano-7-ethoxy-6-(N-acetylamino)quinoline;n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide;N-(4-CHLORO-3-CYANO-7-ETHOXYQUINOLINE-6-YL)ACETAMIDE
CBNumber
CB6947307
Molecular Formula
C14H12ClN3O2
Formula Weight
289.72
MOL File
848133-76-6.mol
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n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide Property

Melting point:
250°C(lit.)
Boiling point:
518.6±45.0 °C(Predicted)
Density 
1.35±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly, Heated)
form 
Solid
pka
13.13±0.43(Predicted)
color 
Light Yellow
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Safety

Hazard Codes 
Xn
Risk Statements 
22
HS Code 
2933.49.7000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CVT00119
Product name
N-(4-chloro-3-cyano-7-ethoxyquinolin-6-yl)acetamide
Packaging
1g
Price
$964
Updated
2024/03/01
TCI Chemical
Product number
C3315
Product name
N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide
Purity
>98.0%(HPLC)(N)
Packaging
1g
Price
$69
Updated
2024/03/01
TCI Chemical
Product number
C3315
Product name
N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide
Purity
>98.0%(HPLC)(N)
Packaging
5g
Price
$206
Updated
2024/03/01
TRC
Product number
C365013
Product name
N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide
Packaging
1g
Price
$70
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC146854
Product name
N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide
Packaging
500mg
Price
$75
Updated
2021/12/16
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n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide Chemical Properties,Usage,Production

Chemical Properties

yellow powder

Uses

N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide is used in synthesis of an antitumor agent, neratinib (N390090).

n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide Preparation Products And Raw materials

Raw materials

Preparation Products

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n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide Suppliers

Americas 1 China 175 Europe 1 India 6 Japan 1 United Kingdom 3 United States 18 Global 205
Jinan XuanDe Chemical Co., Ltd.
Tel
0531-88803958; 18866891188
Fax
0531-82777287
Email
zhaojiangxia@shiningpharm.com
Country
China
ProdList
264
Advantage
58
Shanghai jing Hao pharmaceutical technology co., LTD
Tel
021-68900963 15618693615
Fax
021-68900963
Email
sales@jinghaopharma.com
Country
China
ProdList
310
Advantage
58
QINGDAO SYSTEMCHEM CO,.LTD.
Tel
15066846586 15712728865 13713086161 13668866880
Fax
0532-66085265
Email
37904322@qq.com
Country
China
ProdList
68
Advantage
58
TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD.
Tel
022-60182192,1339732154 18722583064
Fax
86-22-60979672
Email
marketing@pharmacn.com
Country
China
ProdList
112
Advantage
61
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Shanghai Boc Chemical Co.,Ltd
Tel
021-34975603-808 18721111801
Fax
+86-21-34975602-805
Email
sales@bocpharma.com
Country
China
ProdList
994
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Zhejiang Qiming Pharmaceutical Co., Ltd.
Tel
+86-571-87163895 +86-571-87163893
Fax
+86-571-87163816
Email
sales@qimingpharm.com
Country
China
ProdList
87
Advantage
65
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View Lastest Price from n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide manufacturers

Nanjing Fred Technology Co., Ltd
Product
N-(4-chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide 848133-76-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2024-01-03
Weijer International Trade (Hebei) Co., Ltd
Product
N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide 848133-76-6
Price
US $80.00/KG
Min. Order
1KG
Purity
>99%
Supply Ability
20tons
Release date
2023-03-13
Weijer International Trade (Hebei) Co., Ltd
Product
N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)acetamide 848133-76-6
Price
US $80.00/KG
Min. Order
1KG
Purity
>99%
Supply Ability
20tons
Release date
2023-03-13

848133-76-6, n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide Related Search:

N-Pyridin-2-yl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamide 6-AMINO-4-CHLORO-7-ETHOXYQUINOLINE-3-CARBONITRILE 6-AMino-4-((3-chloro-4-(pyridin-2-ylMethoxy)phenyl)aMino)-7-ethoxyquinoline-3-carbonitrile (Hydrochloride) 2-(4-Nitro-2-ethoxyphenyl)pthaliMide 4-Chloro-3-cyano-7-ethoxy-6-nitroquinoline 2-[(2-Chloro-4-nitrophenoxy)methyl]pyridine N-(3-cyano-7-ethoxy-4-oxo-1,4-dihydroquinolin-6-yl)acetamide 2-(4-AMino-2-ethoxyphenyl)pthaliMide 6-amino-4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-7-ethoxyquinoline-3-carbonitrile 3-chloro-4-(pyridin-2-ylmethoxy)aniline Neratinib N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-aminoquinazolin-4-aMine N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-nitroquinazolin-4-aMine N-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methacrylamide N'-(4-Amino-2-cyanophenyl)-N,N-dimethylformamidine N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide N-(4-broMo-2-isopropylphenyl)acetaMide

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  • N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)
  • n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide
  • N-(4-CHLORO-3-CYANO-7-ETHOXY-6-QUINOLINYL) ACETAMI
  • Acetamide, N-(4-chloro-3-cyano-7-ethoxy-6-quinolinyl)-
  • 4-chloro-3-cyano-7-ethoxy-6-N-acetylquinoline
  • N-(4-chloro-3-cyano-7-ethoxyquinolin-6-yl)acetaMide
  • Neratinib Intermediate 2
  • n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide(848133-76-6)
  • 6-Acetamido-4-chloro-7-ethoxyquinoline-3-carbonitrile
  • 4-Chloro-3-cyano-7-ethoxy-6-(acetylamino)quinoline
  • n-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl) acetamide ISO 9001：2015 REACH
  • Neratinib Impurity 40
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  • 848133-76-6
  • 848133-76-6