ChemicalBook > CAS DataBase List > Raubasine
Raubasine
- Product Name
- Raubasine
- CAS No.
- 483-04-5
- Chemical Name
- Raubasine
- Synonyms
- Tensyl;Sarpan;Vincain;Vincein;Lamuran;Ranitol;RAUBASIN;Vinceine;Vincaine;Raubasil
- CBNumber
- CB7129678
- Molecular Formula
- C21H24N2O3
- Formula Weight
- 352.43
- MOL File
- 483-04-5.mol
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Raubasine Property
- Melting point:
- 258°C (rough estimate)
- Boiling point:
- 486.04°C (rough estimate)
- alpha
- D20 -60° (c = 0.5 in chloroform); D20 -45° (c = 0.5 in pyridine); D20 -39° (c = 0.25 in methanol)
- Density
- 1.1823 (rough estimate)
- refractive index
- 1.6500 (estimate)
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Methanol (Slightly, Heated)
- form
- Solid
- pka
- pK1:10.55(+1) (25°C)
- color
- Pale Yellow
- optical activity
- [α]/D -65±3°, c = 1 in chloroform
- Water Solubility
- insoluble in water
- BRN
- 97268
- LogP
- 2.880 (est)
- NIST Chemistry Reference
- Ajmalicine(483-04-5)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H300Fatal if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P405Store locked up.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 41111
- Product name
- Ajmalicine
- Purity
- ≥98.0% (HPLC)
- Packaging
- 50mg
- Price
- $112.4
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 41111
- Product name
- Ajmalicine
- Purity
- ≥98.0% (HPLC)
- Packaging
- 10mg
- Price
- $77.7
- Updated
- 2023/06/20
Sigma-Aldrich
- Product number
- R751618
- Product name
- AJMALICINE
- Purity
- AldrichCPR
- Packaging
- 50MG
- Price
- $97.9
- Updated
- 2022/05/15
TRC
- Product number
- R127000
- Product name
- Raubasine
- Packaging
- 50mg
- Price
- $185
- Updated
- 2021/12/16
Usbiological
- Product number
- 288595
- Product name
- Raubasine
- Packaging
- 5g
- Price
- $345
- Updated
- 2021/12/16
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Raubasine Chemical Properties,Usage,Production
Description
Vinca rosea L. yields this alkaloid which crystallizes as colourless needles from MeOH. The base is laevorotatory having a specific rotation of [α]D_620 (MeOH) and forms a crystalline hydrochloride, m.p. 281-3°e. The structure given above has been elucidated from chemical and spectroscopic data.
Uses
Antihypertensive, anti-ischemic.
Uses
Antihypertensive, anti-ischemic (cerebral and peripheral)
Definition
ChEBI: Ajmalicine is a monoterpenoid indole alkaloid with formula C21H24N2O3, isolated from several Rauvolfia and Catharanthus species. It is a selective alpha1-adrenoceptor antagonist used for the treatment of high blood pressure. It has a role as an antihypertensive agent, an alpha-adrenergic antagonist and a vasodilator agent. It is a monoterpenoid indole alkaloid, a methyl ester and an organic heteropentacyclic compound. It is a conjugate base of an ajmalicine(1+).
target
P450 (e.g. CYP17)
Purification Methods
It crystallises from MeOH, EtOH or EtOAc. [Beilstein 27 III/IV 7927.]
References
Janot, Le Men, Cornpt. Rend., 243, 1786 (1956) Shamma, Moss, J. Arner. Chern. Soc., 83, 5038 (1961) Abdurakhsimova, Yuldashev, Yunusov, Khirn. Prir. Soedin., 1,224 (1965)
Raubasine Preparation Products And Raw materials
Raw materials
Preparation Products
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Raubasine Suppliers
- Tel
- +86-21-20908456
- Fax
- 021-58180499
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- China
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- 6005
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- 1-(800)-881-8210
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- United States
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- China
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- 0871-65215563
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- China
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- China
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- 0086-21-51320502
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- China
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- Fax
- +86 (20) 39218032
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- China
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- 0755-28363542
- sales@chem-strong.com
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- China
- ProdList
- 18070
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View Lastest Price from Raubasine manufacturers
Hebei Weibang Biotechnology Co., Ltd
- Product
- Raubasine 483-04-5
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-07
Hebei Fengqiang Trading Co., LTD
- Product
- Raubasine 483-04-5
- Price
- US $100.00/bag
- Min. Order
- 1bag
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2023-09-14
Henan Bao Enluo International TradeCo.，LTD
- Product
- Raubasine 483-04-5
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 99.9%
- Supply Ability
- 10000MT
- Release date
- 2023-08-17
483-04-5, RaubasineRelated Search:
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4-Piperidineethanol
1,2,3,4-TETRAHYDRO-9H-PYRIDO[3,4-B]INDOLE
Isobutyl vinyl ether
RAUBASINE HYDROCHLORIDE,δ-Yohimbine hydrochloride, Raubasine hydrochloride
1-METHYL-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE
(1-Methyl-piperidin-4-yl)-acetaldehyde
Vinyl isopropyl ether
2,4-Dimethylpiperidine
AJMALINE