4-Piperidineethanol
- Product Name
- 4-Piperidineethanol
- CAS No.
- 622-26-4
- Chemical Name
- 4-Piperidineethanol
- Synonyms
- 2-(Piperidin-4-yl)ethan-1-ol;2-Piperidin-4-ylethanol;4-(2-HYDROXYETHYL)PIPERIDINE;4-Piperineethanol;4-ethanolpiperidine;4-PIPERIDINEETHANOL;piperidine-4-ethanol;PIPERIDIN-4-YLETHANOL;PIPERIDINEETHANOL(4-);Tirofiban Impurity 58
- CBNumber
- CB5151899
- Molecular Formula
- C7H15NO
- Formula Weight
- 129.2
- MOL File
- 622-26-4.mol
4-Piperidineethanol Property
- Melting point:
- 46-47 °C (lit.)
- Boiling point:
- 131-136 °C/17 mmHg (lit.)
- Density
- 1.0059
- refractive index
- n20/D 1.4902(lit.)
- Flash point:
- >230 °F
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Oil
- pka
- 15.10±0.10(Predicted)
- color
- Brown
- InChI
- InChI=1S/C7H15NO/c9-6-3-7-1-4-8-5-2-7/h7-9H,1-6H2
- InChIKey
- LDSQQXKSEFZAPE-UHFFFAOYSA-N
- SMILES
- N1CCC(CCO)CC1
- CAS DataBase Reference
- 622-26-4(CAS DataBase Reference)
- NIST Chemistry Reference
- 4-Ethanolpiperidine(622-26-4)
- EPA Substance Registry System
- 4-Piperidineethanol (622-26-4)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-37/39-24/25
- WGK Germany
- 3
- Hazard Note
- Irritant
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P46156
- Product name
- 4-Piperidineethanol
- Purity
- 97%
- Packaging
- 1g
- Price
- $69
- Updated
- 2023/06/20
- Product number
- P46156
- Product name
- 4-Piperidineethanol
- Purity
- 97%
- Packaging
- 5g
- Price
- $74
- Updated
- 2023/01/07
- Product number
- P0992
- Product name
- 4-Piperidineethanol
- Purity
- >96.0%(GC)(T)
- Packaging
- 5g
- Price
- $70
- Updated
- 2025/07/31
- Product number
- P0992
- Product name
- 4-Piperidineethanol
- Purity
- >96.0%(GC)(T)
- Packaging
- 25g
- Price
- $282
- Updated
- 2025/07/31
- Product number
- P481960
- Product name
- 4-Piperidineethanol
- Packaging
- 2.5g
- Price
- $130
- Updated
- 2021/12/16
4-Piperidineethanol Chemical Properties,Usage,Production
Chemical Properties
white crystalline low melting solid
Uses
Reactant for synthesis of:• ;Ursolic acid derivatives1• ;Amodiaquine analogues for treatment of cerebral malaria2• ;Spiroimidazolidinone NPC1L1 inhibitors3• ;Piperazinyl glutamate pyridines as orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation4• ;Neurokinin-2 receptor antagonists5• ;Hepatitis C virus NS5B polymerase inhibitors6
Uses
4-Piperidineethanol have been used as a intermediate in the synthetic preparation of cellular-active allosteric inhibitors of FAK
Uses
4-Piperidineethanol have been used as an intermediate in the synthetic preparation of cellular-active allosteric inhibitors of FAK
Synthesis
51052-78-9
622-26-4
Lithium tetrahydroaluminum (0.06 mol) was added to ice-bath cooled anhydrous tetrahydrofuran (80 mL) under nitrogen protection, followed by the slow addition of crushed 4-piperidineacetic acid (4.95 g, 0.03 mol), and the temperature of the reaction was controlled to be no more than 30 °C. The reaction mixture was stirred at 25 °C overnight. Upon completion of the reaction, the system was cooled to 0 °C and water (3 mL), 30% aqueous sodium hydroxide solution (3 mL), and water (3 mL) were added sequentially and slowly dropwise. The resulting mixture was continued to be stirred at 25 °C for 30 min. Finally, the solvent was removed by distillation under reduced pressure to give 2.23 g of light yellow solid product in 62.5% yield.
References
[1] Patent: CN103755686, 2016, B. Location in patent: Paragraph 0099; 0100
4-Piperidineethanol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Piperidineethanol manufacturers
- Product
- 4-Piperidineethanol 622-26-4
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-29
- Product
- 2-(Piperidin-4-yl)ethanol 622-26-4
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99.5%
- Supply Ability
- 100 tons
- Release date
- 2022-02-20
- Product
- 4-Piperidineethanol 622-26-4
- Price
- US $1000.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2018-07-24