ChemicalBook > CAS DataBase List > CHONDROITINASE ABC

CHONDROITINASE ABC

Product Name
CHONDROITINASE ABC
CAS No.
9024-13-9
Chemical Name
CHONDROITINASE ABC
Synonyms
EC 4.2.2.4;units/mg solid;CHONDROITINASE ABC;chondroitinase ABC I;CHONDROITIN ABC LYASE;Lyase, chondroitin ABC;Endolyase, chondroitiBC;chondroitinase-abc bsa free;Chondroitinase ABC, Recomb.;lyophilized powder, 0.3-3 
CBNumber
CB7143258
Molecular Formula
NULL
Formula Weight
0
MOL File
Mol file
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CHONDROITINASE ABC Property

storage temp. 
-20°C
solubility 
0.01% bovine serum albumin aqueous (BSA) solution: soluble
form 
lyophilized powder
color 
White to off-white
biological source
bacterial (Proteus vulgaris)
Specific Activity
50-250units/mg protein
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
10-21
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C3667
Product name
Chondroitinase ABC from Proteus vulgaris
Purity
BSA free, lyophilized powder, specific activity 50-250 units/mg protein
Packaging
5units
Price
$292
Updated
2025/07/31
Sigma-Aldrich
Product number
SAE0150
Product name
Chondroitinase ABC from Proteus vulgaris
Purity
recombinant, low endotoxin, aqueous solution, ≥100 U/ml, 50-250 units/mg protein, BSA free
Packaging
0.1ML
Price
$492
Updated
2025/07/31
Sigma-Aldrich
Product number
C2905
Product name
Chondroitinase ABC from Proteus vulgaris
Purity
lyophilized powder, 0.3-3?units/mg solid
Packaging
2units
Price
$116
Updated
2025/07/31
Sigma-Aldrich
Product number
C3667
Product name
Chondroitinase ABC from Proteus vulgaris
Purity
BSA free, lyophilized powder, specific activity 50-250 units/mg protein
Packaging
10units
Price
$471.2
Updated
2025/07/31
Sigma-Aldrich
Product number
C2905
Product name
Chondroitinase ABC from Proteus vulgaris
Purity
lyophilized powder, 0.3-3?units/mg solid
Packaging
5units
Price
$233
Updated
2025/07/31
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CHONDROITINASE ABC Chemical Properties,Usage,Production

Uses

Chondroitinase ABC from Sigma has been used to digest O-linked chondroitin sulfate-like glycosaminoglycan (CSGAG). The enzyme has also been used to digest glycosaminoglycan chains in proteoglycans during the construction and expression of a recombinant versican gene in mammalian systems. Furthermore, it has been used to digest chondroitin sulfate in the proteoglycan complexes. The enzyme has also been used in the removal of glycan chains from aggrecan, which eliminates the axon growth-inhibitory effect of aggrecan.

Uses

The enzyme has been used to study the consequences of inducing acute, long-lasting changes in chondroitin sulfate proteoglycans using adult rat brain cells. Glycosaminoglycans have been digested with chondroitinase ABC for chondroitin/dermatan sulfate quantitation in keratocyte cell cultures obtained from fresh bovine corneal stromae.

Biochem/physiol Actions

Chondroitinase ABC catalyzes the eliminative degradation of polysaccharides containing (1-4)-β-D-hexosaminyl and (1-3)-β-D-glucuronosyl (or (1-3)-α-L-iduronosyl) linkages to disaccharides containing 4-deoxy-β-D-gluc-4-enuronosyl groups. It acts on chondroitin 4-sulfate, chondroitin 6-sulfate, and dermatan sulfate. However, it acts slowly on hyaluronate. The molecular weight is approximately 120 kDa with 2 non-identical subunits of molecular masses 86 kDa and 32 kDa. The pH optimum is 8.0 with chondroitin sulfate and 6.8 with hyaluronic acid. The optimal temperature is 37 °C. 1 mM Zn2+ acts as an inhibitor, while 0.05 M acetate is an activator of the enzyme.

CHONDROITINASE ABC Preparation Products And Raw materials

Raw materials

Preparation Products

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CHONDROITINASE ABC Suppliers

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9024-13-9, CHONDROITINASE ABCRelated Search:


  • CHONDROITINASE ABC
  • CHONDROITIN ABC LYASE
  • EC 4.2.2.4
  • chondroitinase abc F. proteus vulgaris
  • Chondroitinase ABC from Proteus vulgaris
  • Chondroitinase ABC, Proteus vulgaris*Not available Japan*
  • Chondroitinase ABC, Recomb.
  • chondroitinase-abc bsa free
  • Lyase, chondroitin ABC
  • CHONDROITIN ABC LYASE, FROM PROTEUS VULGARIS
  • Chondroitinase ABC from Proteus vulgaris,Chondroitin ABC Lyase
  • chondroitin-sulfate-ABC endolyase
  • Chondroitinase ABC from Proteus vulgaris, Recombinant
  • Native Proteus vulgaris Chondroitinase ABC
  • chondroitinase ABC I
  • lyophilized powder, 0.3-3&#160
  • units/mg solid
  • Chondroitinase?ABC from <i>Proteus vulgaris</i>
  • Endolyase, chondroitiBC
  • 9024-13-9
  • Biochemicals and Reagents
  • BioChemical
  • Application Index
  • Carbohydrate hydrolysis &amp; PTM analysis
  • Carbohydrate and PTM Analysis
  • Carbohydrate Hydrolysis
  • Enzymes, Inhibitors, and Substrates