ChemicalBook > CAS DataBase List > Piperonylic acid

Piperonylic acid

Product Name
Piperonylic acid
CAS No.
94-53-1
Chemical Name
Piperonylic acid
Synonyms
Benzo[d][1,3]dioxole-5-carboxylic acid;Heliotropic acid;1,3-BENZODIOXOLE-5-CARBOXYLIC ACID;PIPEROYLICACID;3,4-(METHYLENEDIOXY)BENZOIC ACID;AKOS 213-90;Pepper acid;heliotropicacid;PIPERONYLIC ACID;PiperonylicAcid>
CBNumber
CB7162666
Molecular Formula
C8H6O4
Formula Weight
166.13
MOL File
94-53-1.mol
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Piperonylic acid Property

Melting point:
229-231 °C (lit.)
Boiling point:
254.32°C (rough estimate)
Density 
1.3579 (rough estimate)
refractive index 
1.5090 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
4.35±0.20(Predicted)
form 
Powder
color 
Off-white to beige
Water Solubility 
slightly soluble
Merck 
14,7477
BRN 
150206
LogP
0.810 (est)
CAS DataBase Reference
94-53-1(CAS DataBase Reference)
NIST Chemistry Reference
1,3-Benzodioxole-5-carboxylic acid(94-53-1)
EPA Substance Registry System
1,3-Benzodioxole-5-carboxylic acid (94-53-1)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-37/38-41-36/37/38
Safety Statements 
26-36/37/39-37/39
WGK Germany 
3
RTECS 
DF4912765
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29329970
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P49805
Product name
Piperonylic acid
Purity
99%
Packaging
5g
Price
$59
Updated
2024/03/01
Sigma-Aldrich
Product number
P49805
Product name
Piperonylic acid
Purity
99%
Packaging
25g
Price
$98
Updated
2024/03/01
TCI Chemical
Product number
P0459
Product name
Piperonylic Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$50
Updated
2024/03/01
Alfa Aesar
Product number
A14105
Product name
Piperonylic acid, 98+%
Packaging
25g
Price
$59.65
Updated
2024/03/01
Alfa Aesar
Product number
A14105
Product name
Piperonylic acid, 98+%
Packaging
100g
Price
$192
Updated
2024/03/01
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Piperonylic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

Piperonylic Acid is a compound closely mimicking the structure of transcinnamic acid involved in the phenylpropanoid pathway in plant physiology.

Definition

ChEBI: Piperonylic acid is a member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a carboxy group at position 5. It is a natural product isolated from several plant species. It is a selective mechanism-based inactivator of the trans-cinnamate 4-hydroxylase enzyme and exhibits antifungal and skin wound healing properties. It has a role as a plant metabolite, an EC 1.14.14.91 ( trans-cinnamate 4-monooxygenase) inhibitor, a vulnerary and an antifungal agent. It is a member of benzodioxoles, a monocarboxylic acid and an aromatic carboxylic acid. It is a conjugate acid of a piperonylate.

Synthesis Reference(s)

The Journal of Organic Chemistry, 40, p. 3803, 1975 DOI: 10.1021/jo00913a051

Purification Methods

Crystallise the acid from EtOH or water. [Beilstein 19/7 V 300.]

Piperonylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Piperonylic acid Suppliers

Carbosynth
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sales@carbosynth.com
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United Kingdom
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6005
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58
Apollo Scientific Ltd.
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Apin Chemicals Limited (UK)
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United Kingdom
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CARBONE SCIENTIFIC CO.,LTD
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United Kingdom
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6666
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Eurolabs Limited
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United Kingdom
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Fluorochem Ltd
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United Kingdom
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6375
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ARIAC - Armenian Institute of Applied Chemistry
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ariac@web.am
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United Kingdom
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2466
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Fluorochem Ltd.
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Apin Chemicals Ltd.
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VWR International
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United Kingdom
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Atlantic Research Chemicals Ltd.
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United Kingdom
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MOLEKULA Ltd.
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kevinbanks@molekula.com
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View Lastest Price from Piperonylic acid manufacturers

Jinan Finer Chemical Co., Ltd
Product
Piperonylic acid 94-53-1
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
99%
Supply Ability
200mt/year
Release date
2021-07-12
Hebei Weibang Biotechnology Co., Ltd
Product
Piperonylic acid 94-53-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-06
Shaanxi Dideu Medichem Co. Ltd
Product
Piperonylic acid 94-53-1
Price
US $0.00-0.00/KG
Min. Order
10mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-15

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