2-Amino-5-bromo-3-nitropyridine
- Product Name
- 2-Amino-5-bromo-3-nitropyridine
- CAS No.
- 6945-68-2
- Chemical Name
- 2-Amino-5-bromo-3-nitropyridine
- Synonyms
- 5-BROMO-3-NITROPYRIDIN-2-AMINE;6-methyl-5-nitropyridin-3-amine;5-BROMO-3-NITRO-PYRIDIN-2-YLAMINE;TIMTEC-BB SBB006560;5-Brom-3-nitropyridin-2-amin;5-Bromo-3-Nitro-2-Pyridinamine;2-Amino-3-Nitro-5-Bromopyridin;2-AMINO-5-BROMO-3-NITROPYRIDINE;2-Amino-3-nitro-5-bromopyridine;2-Pyridinamine, 5-bromo-3-nitro-
- CBNumber
- CB7169135
- Molecular Formula
- C5H4BrN3O2
- Formula Weight
- 218.01
- MOL File
- 6945-68-2.mol
2-Amino-5-bromo-3-nitropyridine Property
- Melting point:
- 205-208 °C (lit.)
- Boiling point:
- 302.9±37.0 °C(Predicted)
- Density
- 1.9128 (rough estimate)
- refractive index
- 1.6200 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 0.15±0.49(Predicted)
- form
- Solid
- color
- Light yellow to yellow
- BRN
- 383851
- InChI
- InChI=1S/C5H4BrN3O2/c6-3-1-4(9(10)11)5(7)8-2-3/h1-2H,(H2,7,8)
- InChIKey
- QOOCOFOGYRQPPN-UHFFFAOYSA-N
- SMILES
- C1(N)=NC=C(Br)C=C1[N+]([O-])=O
- CAS DataBase Reference
- 6945-68-2(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-37/39-36/37/39-22
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29333999
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A1556
- Product name
- 2-Amino-5-bromo-3-nitropyridine
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $43
- Updated
- 2025/07/31
- Product number
- A1556
- Product name
- 2-Amino-5-bromo-3-nitropyridine
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $129
- Updated
- 2025/07/31
- Product number
- A602445
- Product name
- 2-Amino-5-bromo-3-nitropyridine
- Packaging
- 50g
- Price
- $275
- Updated
- 2021/12/16
- Product number
- J91158
- Product name
- 2-Amino-5-bromo-3-nitropyridine
- Packaging
- 1kg
- Price
- $750
- Updated
- 2021/12/16
- Product number
- JK288983
- Product name
- 2-Amino-5-bromo-3-nitropyridine
- Purity
- 98%
- Packaging
- 25g
- Price
- $188
- Updated
- 2021/12/16
2-Amino-5-bromo-3-nitropyridine Chemical Properties,Usage,Production
Chemical Properties
yellow-brown crystalline powder
Uses
2-Amino-5-bromo-3-nitropyridine may be used in the preparation of azaquinoxalinedione.
General Description
2-Amino-5-bromo-3-nitropyridine is formed as intermediate in the synthesis of 2,3-diaminopyridine.
Synthesis
1072-97-5
6945-68-2
General procedure for the synthesis of 2-amino-3-nitro-5-bromopyridine from 2-amino-5-bromopyridine: 2-amino-5-bromopyridine (0.020 mol) was slowly added to concentrated sulfuric acid that was pre-cooled to 0 °C, maintaining the temperature of the reaction system in the 0-5 °C range. Concentrated nitric acid (1.09 mL, 0.024 mol) was slowly added dropwise with continuous stirring, and the rate of dropwise acceleration was controlled to maintain the reaction temperature in the range of 0-5 °C. After the dropwise addition was completed, the reaction mixture was continued to be stirred at 0-5 °C for 1 hour. Subsequently, the reaction system was slowly warmed to room temperature and stirred overnight at room temperature. Upon completion of the reaction, the mixture was carefully poured into crushed ice and the pH was adjusted to 7-8 with 10% aqueous sodium hydroxide solution. the resulting precipitate was collected by filtration, washed well with cold water and finally dried under vacuum at 60 °C overnight to obtain high purity 2-amino-3-nitro-5-bromopyridine.
References
[1] Chemical Communications, 2013, vol. 49, # 72, p. 7929 - 7931
[2] Tetrahedron, 2003, vol. 59, # 43, p. 8555 - 8570
[3] Tetrahedron, 2014, vol. 70, # 5, p. 1077 - 1083
[4] Patent: US6025366, 2000, A
[5] Journal of the Chemical Society, 1948, p. 1389,1392
2-Amino-5-bromo-3-nitropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Amino-5-bromo-3-nitropyridine Suppliers
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View Lastest Price from 2-Amino-5-bromo-3-nitropyridine manufacturers
- Product
- 2-Amino-5-bromo-3-nitropyridine 6945-68-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-29
- Product
- 2-Amino-5-bromo-3-nitropyridine 6945-68-2
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-27
- Product
- 2-Amino-5-bromo-3-nitropyridine 6945-68-2
- Price
- US $6.00-0.20/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-03