2-Nitro-4-trifluoromethylbenzoic acid
- Product Name
- 2-Nitro-4-trifluoromethylbenzoic acid
- CAS No.
- 320-94-5
- Chemical Name
- 2-Nitro-4-trifluoromethylbenzoic acid
- Synonyms
- 2NTF-BOA;2-Nitro-4-(trifL;BUTTPARK 24\10-94;RARECHEM AL BO 0289;2-Nitro-4-trifluorom;Nitrotrifluoromethylbenzoicacid;Nitro-4-(trifluoroMethyl)benzoi;2-nitro-α,α,α-trifluor-p-toluic acid;α,α,α-Trifluoro-2-nitro-p-toluic Acid;2-NITRO-4-(TRIFLUOROMETHYL)BENZOIC ACID
- CBNumber
- CB7215186
- Molecular Formula
- C8H4F3NO4
- Formula Weight
- 235.12
- MOL File
- 320-94-5.mol
2-Nitro-4-trifluoromethylbenzoic acid Property
- Melting point:
- 134-138 °C(lit.)
- Boiling point:
- 306.6±42.0 °C(Predicted)
- Density
- 1.596±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO, Methanol
- pka
- 1.70±0.25(Predicted)
- form
- Crystalline Powder
- color
- Pale yellow
- BRN
- 1985588
- CAS DataBase Reference
- 320-94-5(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 328901
- Product name
- 2-Nitro-4-(trifluoromethyl)benzoic acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $24.5
- Updated
- 2025/07/31
- Product number
- N0720
- Product name
- 2-Nitro-4-(trifluoromethyl)benzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $40
- Updated
- 2025/07/31
- Product number
- N0720
- Product name
- 2-Nitro-4-(trifluoromethyl)benzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $157
- Updated
- 2025/07/31
- Product number
- N596800
- Product name
- 2-Nitro-4-(trifluoromethyl)benzoic Acid
- Packaging
- 10g
- Price
- $145
- Updated
- 2021/12/16
- Product number
- N596800
- Product name
- 2-Nitro-4-(trifluoromethyl)benzoic Acid
- Packaging
- 50g
- Price
- $495
- Updated
- 2021/12/16
2-Nitro-4-trifluoromethylbenzoic acid Chemical Properties,Usage,Production
Chemical Properties
Off-White to Pale Yellow Solid
Uses
2-Nitro-4-(trifluoromethyl)benzoic Acid (cas# 320-94-5) is a compound useful in organic synthesis.
Synthesis
455-24-3
320-94-5
Example 2 a) Synthesis of 2-nitro-4-trifluoromethylbenzoic acid: 11.97 g (63 mmol) of 4-trifluoromethylbenzoic acid was slowly added in batches to 48 mL of concentrated nitric acid (100%) at room temperature. Subsequently, the reaction mixture was heated to reflux for 1 h. After completion of the reaction, it was cooled to room temperature and slowly poured into about 600 g of ice. After stirring the mixture for 1 hour, the precipitate was collected by filtration and washed with 1 L of water. The filtrate was extracted with 300 mL of dichloromethane (CH2Cl2), the organic phase was combined with the precipitate and dried over anhydrous sodium sulfate (Na2SO4). The solvent was removed by distillation under reduced pressure and the residue was recrystallized by dissolving in 1 L of diisopropyl ether (DIP) and adding 2 L of heptane (HEP) at 68 °C, followed by slow cooling of the solution to room temperature. The crystalline product was washed with 1 L of heptane and dried under reduced pressure to give 7.1 g (48% yield) of 2-nitro-4-trifluoromethylbenzoic acid with a melting point of 136 °C - 138 °C.
References
[1] Patent: US2005/124681, 2005, A1. Location in patent: Page/Page column 16
2-Nitro-4-trifluoromethylbenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Nitro-4-trifluoromethylbenzoic acid manufacturers
- Product
- 2-Nitro-4-trifluoromethylbenzoic acid 320-94-5
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 ton
- Release date
- 2024-11-18
- Product
- 2-Nitro-4-(trifluoromethyl)benzoic acid 320-94-5
- Price
- US $1500.00/KG
- Min. Order
- 1KG
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2025-04-14
- Product
- 2-Nitro-4-trifluoromethylbenzoic acid 320-94-5
- Price
- US $0.00/KG
- Min. Order
- 1Kg/Bag
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2021-04-14