BOC-SER(ME)-OH

Product Name: BOC-SER(ME)-OH
CAS No.: 51293-47-1
Chemical Name: BOC-SER(ME)-OH
Synonyms: BOC-O-METHYL-L-SERINE;BOC-SER(ME)-OH;BOC-L-Ser（Me）-OH;Boc-O-Methyl-L-Se;BOC-O-METHYL-L-SER;BOC-SER(ME)-OH DCHA;BOC-SERINE(ME)-OH DCHA;N-Boc-O-methyl-L-serine;BOC-L-SERINE(METHYL ETHER);BOC-O-METHYL-L-SERINE DCHA
CBNumber: CB7218147
Molecular Formula: C9H17NO5
Formula Weight: 219.24
MOL File: 51293-47-1.mol

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BOC-SER(ME)-OH Property

Boiling point:: 355.8±37.0 °C(Predicted)
Density: 1.148±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
form: solid
pka: 3.52±0.10(Predicted)
color: Yellow-brown
InChI: InChI=1S/C9H17NO5/c1-9(2,3)15-8(13)10-6(5-14-4)7(11)12/h6H,5H2,1-4H3,(H,10,13)(H,11,12)/t6-/m0/s1
InChIKey: RFGMSGRWQUMJIR-LURJTMIESA-N
SMILES: C(O)(=O)[C@H](COC)NC(OC(C)(C)C)=O
CAS DataBase Reference: 51293-47-1(CAS DataBase Reference)

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Safety

HazardClass: IRRITANT
HS Code: 2924297099

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B673128
Product name: Boc-Ser(Me)-OH
Packaging: 250mg
Price: $50
Updated: 2021/12/16

Activate Scientific

Product number: AS29499
Product name: N-Boc-O-methyl-L-serine
Purity: 95+% ee
Packaging: 1g
Price: $52
Updated: 2021/12/16

Chem-Impex

Product number: 05599
Product name: Boc-O-methyl-L-serinedicyclohexylammoniumsalt,≥98.5%(HPLC)
Purity: ≥98.5%(HPLC)
Packaging: 1G
Price: $58.24
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4158-1-S7
Product name: (2S)-2-Amino-3-methoxypropanoic acid, N-Boc protected
Packaging: 1g
Price: $63
Updated: 2021/12/16

Apolloscientific

Product number: OR307095
Product name: (2S)-2-Amino-3-methoxypropanoicacid,N-BOCprotected
Packaging: 1g
Price: $29
Updated: 2021/12/16

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BOC-SER(ME)-OH Chemical Properties,Usage,Production

Chemical Properties

White to off-white crystals

Uses

BOC-SER(ME)-OH, also known as Boc-Ser-OMe or N-tert-butyloxycarbonyl-L-serine methyl ester, is an amino acid derivative commonly used in peptide synthesis.

Synthesis

4219-94-7

24424-99-5

51293-47-1

General procedure for the synthesis of N-Boc-O-methyl-L-serine from O-methyl DL-serine and di-tert-butyl dicarbonate: 35 mL of aqueous 1 N sodium hydroxide solution and 35 mL of tetrahydrofuran (THF) were added to 2.0 g (17 mmol) of O-methyl DL-serine. With stirring at 0 °C, a solution of di-tert-butyl dicarbonate (4.03 g, 18.5 mmol) in THF (15 mL) was added slowly. The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the reaction mixture was concentrated by evaporation under reduced pressure. The aqueous phase was acidified to pH 4-5 with 10% aqueous citric acid and then extracted with ethyl acetate. The organic phase was washed with saturated brine, dried over anhydrous magnesium sulfate, and the solvent was evaporated under reduced pressure to give 3.6 g of N-Boc-O-methyl-L-serine (98% yield). Mass spectrum (ESI) m/z: 220.1 (M + H)+.

References

[1] Chemistry - A European Journal, 2011, vol. 17, # 15, p. 4183 - 4194
[2] Patent: WO2016/11088, 2016, A2. Location in patent: Paragraph 00238; 00239

BOC-SER(ME)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-SER(ME)-OH Suppliers

China 188 Germany 3 India 3 Japan 2 Switzerland 1 United Kingdom 6 United States 25 Global 228

A.J Chemicals

Tel: --
Fax: --
Email: sales@ajchem.in
Country: India
ProdList: 6100
Advantage: 58

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View Lastest Price from BOC-SER(ME)-OH manufacturers

Sichuan Jiaying Lai Technology Co.,LTD

Product: Boc-ser(me)-OH 51293-47-1
Price: US $1.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 100KG
Release date: 2019-07-22

Career Henan Chemical Co

Product: BOC-SER(ME)-OH 51293-47-1
Price: US $100.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2018-07-30

51293-47-1, BOC-SER(ME)-OHRelated Search:

Boc-Ser(tBu)-OH (dicyclohexylammonium) salt,Boc-Ser(tBu)-OH Dicyclohexylamine Salt,Boc-Ser(Tbu)-Ohcha,Boc-Ser(tBu)-OH&#8226,BOC-SER(TBU)-OH DCHA BOC-SER(ME)-OH Boc-O-tert-butyl-L-threonine Boc-Ser(tBu)-OH 3-FLUORO-5-(TRIFLUOROMETHYL)PHENOL Boc-Thr(Bzl)-OH (S)-(-)-3-TERT-BUTOXYCARBONYL-4-METHOXYCARBONYL-2,2-DIMETHYL-1,3-OXAZOLIDINE BOC-THR(ME)-OH BOC-Ser (Obzl) OH,BOC-SER(BUT)-OH,BOC-SER(BU)-OH,BOC-SER(TBU)-OH BOC-SER(BU)-OH,BOC-SER(BUT)-OH,BOC-SER(TBU)-OH Boc-D-Ser(Bzl)-OH BOC-L-Serine L-Serine BOC-SER(BZL)-OH DCHA BOC-L-THR(ALLOC)-OH DCHA BOC-SER(BZL)-OSU BOC-O-BENZYL-L-THREONINE N-CARBOXY ANHYDRIDE Boc-Ser(Aloc)-OH·DCHA

BOC-L-Ser（Me）-OH

(2S)-2-(tert-Butoxycarbonylamino)-3-methoxy-propanoic acid

(S)-N-BOC-2-AMINO-3-METHOXY-PROPIONIC ACID

N-ALPHA-T-BUTOXYCARBONYL-O-METHYL-L-SERINE

N-ALPHA-T-BUTOXYCARBONYL-O-METHYL-L-SERINE DICYCLOHEXYLAMMONIUM SALT

N-ALPHA-T-BOC-O-METHYL-L-SERINE

BOC-(S)-2-AMINO-3-METHOXYLPROPANOIC ACID

BOC-(S)-2-AMINO-3-METHOXYPROPIONIC ACID

BOC-SER(ME)-OH

BOC-SER(ME)-OH DCHA

BOC-SERINE(ME)-OH DCHA

Boc-O-methyl-L-serine dicyclohexylammonium salt≥ 98.5% (HPLC)

BOC-L-SERINE(METHYL ETHER)

BOC-O-METHYL-L-SER

BOC-O-METHYL-L-SERINE

BOC-O-METHYL-L-SERINE DCHA

BOC-O-METHYL-L-SERINE DICYCLOHEXYLAMMONIUM SALT

Boc-O-methyl-L-Serinedicyclohexylamine salt

Boc-O-Methyl-L-Se

N-tert-Butoxycarbonyl-O-methyl-L-serine

(S)-2-(tert-butoxycarbonylamino)-3-methoxypropanoicacid

L-Serine, N-[(1,1-diMethylethoxy)carbonyl]-O-Methyl-

Boc-Ser(Me)-OH·DCHA Boc-O-Methyl-L-SerinedicyclohexylaMine salt

N-Boc-O-Methyl-L-serine, 97%

(2S)-2-Amino-3-methoxypropanoic acid, N-BOC protected

N-Boc-O-methyl-L-serine,97%

(S)-N-Boc-2-Amino-3-Methoxy-PropionicAci

N-α-(t-Butoxycarbonyl)-O-methyl-L-serine

N-tert-butoxycarbonyl-(S)-O-methyl-serin

N-[(1,1-Dimethylethoxy)carbonyl]-O-methyl-L-serine

(2S)-3-methoxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid

N-Boc-O-methyl-L-serine

51293-47-1

C9H17NO5C12H23N

unnatural amino acids

Boc-Amino acid series

Serine [Ser, S]

Boc-Amino Acids and Derivative

API