ChemicalBook > CAS DataBase List > 2-Amino-5-nitrobenzophenone

2-Amino-5-nitrobenzophenone

Product Name
2-Amino-5-nitrobenzophenone
CAS No.
1775-95-7
Chemical Name
2-Amino-5-nitrobenzophenone
Synonyms
Ro 7-1999;Ro 7-19990;TIMTEC-BB SBB000821;IFLAB-BB F0266-0701;Nitrazepam Impurity 2;Nitrazepam Impurity B;Ciclopirox Impurity 6;LABOTEST-BB LT00000253;2-Benzoyl-4-nitroaniline;Nitrazepam EP Impurity B
CBNumber
CB7242568
Molecular Formula
C13H10N2O3
Formula Weight
242.23
MOL File
1775-95-7.mol
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2-Amino-5-nitrobenzophenone Property

Melting point:
166-168 °C (lit.)
Boiling point:
385.05°C (rough estimate)
Density 
1.2480 (rough estimate)
refractive index 
1.5300 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
-2.26±0.36(Predicted)
color 
Beige
Water Solubility 
3 mg/L (20 C)
InChI
InChI=1S/C13H10N2O3/c14-12-7-6-10(15(17)18)8-11(12)13(16)9-4-2-1-3-5-9/h1-8H,14H2
InChIKey
PZPZDEIASIKHPY-UHFFFAOYSA-N
SMILES
C(C1=CC([N+]([O-])=O)=CC=C1N)(C1=CC=CC=C1)=O
CAS DataBase Reference
1775-95-7(CAS DataBase Reference)
NIST Chemistry Reference
Methanone, (2-amino-5-nitrophenyl)phenyl-(1775-95-7)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22
Safety Statements 
26-37/39-36
WGK Germany 
3
RTECS 
PC4935000
HS Code 
29223990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
211737
Product name
2-Amino-5-nitrobenzophenone
Purity
≥98%
Packaging
25g
Price
$39.83
Updated
2025/07/31
Sigma-Aldrich
Product number
211737
Product name
2-Amino-5-nitrobenzophenone
Purity
≥98%
Packaging
100g
Price
$79
Updated
2025/07/31
TCI Chemical
Product number
A1134
Product name
2-Amino-5-nitrobenzophenone
Purity
>98.0%(HPLC)
Packaging
25g
Price
$62
Updated
2025/07/31
TRC
Product number
A618400
Product name
2-Amino-5-nitrobenzophenone
Packaging
10g
Price
$135
Updated
2021/12/16
Usbiological
Product number
002415
Product name
5-Amino-2-nitrobenzophenone
Packaging
2.5g
Price
$403
Updated
2021/12/16
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2-Amino-5-nitrobenzophenone Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

2-Amino-5-nitrobenzophenone was used in the synthesis of [5-(4-nitrophenyl)-2-furyl]acrylic acid substituted benzophenone (anti-malarial agent).

Uses

A metabolite of Nitrazepam

Synthesis Reference(s)

Synthetic Communications, 16, p. 485, 1986 DOI: 10.1080/00397918608057727

General Description

FT-IR and Raman spectra of 2-amino-5-nitrobenzophenone (ANBP) has been reported.

Synthesis

17420-30-3

873-55-2

1775-95-7

2-Cyano-4-nitroaniline (0.3 mmol), sodium benzenesulfinate (0.6 mmol), palladium acetate (10 mol%), 2,2'-bipyridine (20 mol%), p-nitrobenzenesulfonic acid (10 equiv.), tetrahydrofuran (2 mL), and water (1 mL) were sequentially added to a Schlenk tube under the protection of nitrogen atmosphere. The reaction mixture was stirred vigorously at 80 °C for 48 hours. After completion of the reaction, the mixture was poured into ethyl acetate and washed sequentially with saturated sodium bicarbonate solution (2 x 10 mL) and saturated saline (1 x 10 mL). After the aqueous layer was extracted with ethyl acetate, all organic layers were combined and dried with anhydrous magnesium sulfate. The solvent was removed by concentration under reduced pressure and the residue was purified by fast column chromatography (eluent: hexane/ethyl acetate) to afford the target product 2-amino-5-nitrobenzophenone.

References

[1] Molecules, 2014, vol. 19, # 5, p. 6439 - 6449

2-Amino-5-nitrobenzophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Amino-5-nitrobenzophenone manufacturers

Baoji Guokang Healthchem co.,ltd
Product
2-Amino-5-nitrobenzophenone 1775-95-7
Price
US $127.10/g
Min. Order
500g
Purity
99%
Supply Ability
5000g
Release date
2021-06-08
Career Henan Chemical Co
Product
2-Amino-5-nitrobenzophenone 1775-95-7
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
Customized
Release date
2018-12-20

1775-95-7, 2-Amino-5-nitrobenzophenoneRelated Search:


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  • 2-Amino-5-nitrodiphenylmethone
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  • Nitrazepam Impurity Ⅰ:2-Amino-5-nitrobenzophenone
  • 1775-95-7
  • 1778-95-7
  • C13H10N203
  • Ketones
  • Organic Building Blocks
  • AMINE
  • Carbonyl Compounds
  • C13 to C14
  • Building Blocks
  • Building Blocks
  • C13 to C14
  • Carbonyl Compounds
  • Chemical Synthesis
  • Organic Building Blocks
  • Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • FINE Chemical & INTERMEDIATES
  • Aromatic Benzophenones & Derivatives (substituted)
  • Various Metabolites and Impurities
  • Nitrazepam
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • C13 to C14
  • Carbonyl Compounds
  • Ketones