2-BROMO-4-CYANOTHIAZOLE
- Product Name
- 2-BROMO-4-CYANOTHIAZOLE
- CAS No.
- 848501-90-6
- Chemical Name
- 2-BROMO-4-CYANOTHIAZOLE
- Synonyms
- 2-bromo-1,3-thiazole-4-carbonitrile;2-BROMO-4-CYANOTHIAZOLE;2-bromo-4-thiazolecarbonitrile;4-Thiazolecarbonitrile, 2-broMo-
- CBNumber
- CB72452776
- Molecular Formula
- C4HBrN2S
- Formula Weight
- 189.03
- MOL File
- 848501-90-6.mol
2-BROMO-4-CYANOTHIAZOLE Property
- Boiling point:
- 276.1±13.0 °C(Predicted)
- Density
- 1.97±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -3.33±0.10(Predicted)
- Appearance
- Off-white to light yellow Solid
Safety
- HS Code
- 2934100090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B685573
- Product name
- 2-Bromo-4-cyanothiazole
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- P000122417
- Product name
- 2-Bromo-4-cyanothiazole
- Purity
- 95+%
- Packaging
- 1g
- Price
- $73
- Updated
- 2021/12/16
- Product number
- 072295
- Product name
- 2-Bromo-4-cyanothiazole
- Purity
- 95+%
- Packaging
- 1g
- Price
- $99
- Updated
- 2021/12/16
- Product number
- P000122417
- Product name
- 2-Bromo-4-cyanothiazole
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $18
- Updated
- 2021/12/16
- Product number
- P000122417
- Product name
- 2-Bromo-4-cyanothiazole
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $26
- Updated
- 2021/12/16
2-BROMO-4-CYANOTHIAZOLE Chemical Properties,Usage,Production
Synthesis
848501-94-0
848501-90-6
The general procedure for synthesizing 2-bromo-4-cyanothiazole using 2-bromothiazole-4-carboxamide as starting material is as follows: General method: after completing the preparation of the amide intermediate (Example A), the state of the reaction vessel is determined according to the boiling point of the amide intermediate. If the boiling point of the amide intermediate at atmospheric pressure is equal to or lower than the set reaction temperature (TB), the reaction vessel is closed; if the boiling point is higher than the TB, the reaction vessel is kept open. Subsequently, stirring is continued at a rate of 600 rpm and the reaction temperature is adjusted to TB. this temperature (TB) is maintained for a continuous period of TD hours until the reaction is nearly complete. Next, the reaction vessel was sealed and connected to a vacuum pump, the vacuum in the reaction vessel was adjusted to 20-50 mbar (depending on the nature of the nitrile product) and the distillate was collected as the nitrile product. The yield of the nitrile product was calculated, and samples were taken for NMR spectroscopy and elemental analysis to characterize the resulting nitrile product. The specific reaction conditions and characterization results are detailed in Tables A-7, A-8, A-9, A-10 and A-11. The characterization results showed that the obtained nitrile product was of very high purity (>99%). In some embodiments of the preparation of the nitrile product, 10 g of phosphorus pentoxide can be selectively added as a catalyst at the initial stage of the reaction.
References
[1] Patent: CN104557357, 2018, B. Location in patent: Paragraph 0150; 0151; 0152; 0162
[2] Patent: WO2011/109799, 2011, A1. Location in patent: Page/Page column 225
2-BROMO-4-CYANOTHIAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-BROMO-4-CYANOTHIAZOLE manufacturers
- Product
- 2-BROMO-4-CYANOTHIAZOLE 848501-90-6
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 99
- Supply Ability
- 100kg
- Release date
- 2019-07-10