ChemicalBook > CAS DataBase List > 4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one

4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one

Product Name: 4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one
CAS No.: 1252018-10-2
Chemical Name: 4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one
Synonyms: Rivaroxaban Impurity 236;(R)-4-[4-[(3-Chloro-2-hydroxypropyl)amino]phenyl]morpholin-3-one;3-Morpholinone, 4-[4-[[(2R)-3-chloro-2-hydroxypropyl]amino]phenyl]-;4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one;1252018-10-2,4-[4-(N-(3-CHLORO-(2R)-2-HYDROXY-1-PROPYL)AMINO)PHENYL]MORPHOLIN-3-ONE;4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-p ropyl)amino)phenyl]morpholin-3-one 2-[(2R)-2-hydroxy-3-{[4-(3-oxomorph olin-4-yl)phenyl]amino}propyl]-1H-is oindole-1,3(2H)-dione 2-[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpho linyl)phenyl]-5-oxazolidinyl]methyl]-1H-isoindole-1
CBNumber: CB72670660
Molecular Formula: C13H17ClN2O3
Formula Weight: 284.74
MOL File: 1252018-10-2.mol

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4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one Property

Boiling point:: 604.5±55.0 °C(Predicted)
Density: 1.349±0.06 g/cm3(Predicted)
solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka: 13.53±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: C292820
Product name: 4-[4-[[(2R)-3-Chloro-2-hydroxypropyl]amino]phenyl]-3-morpholinone
Packaging: 25mg
Price: $235
Updated: 2021/12/16

TRC

Product number: C292820
Product name: 4-[4-[[(2R)-3-Chloro-2-hydroxypropyl]amino]phenyl]-3-morpholinone
Packaging: 50mg
Price: $470
Updated: 2021/12/16

TRC

Product number: C292820
Product name: 4-[4-[[(2R)-3-Chloro-2-hydroxypropyl]amino]phenyl]-3-morpholinone
Packaging: 100mg
Price: $915
Updated: 2021/12/16

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4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one Chemical Properties,Usage,Production

Uses

4-[4-[[(2R)-3-Chloro-2-hydroxypropyl]amino]phenyl]-3-morpholinone (Rivaroxaban Impurity E) is an impurity of Rivaroxaban (R538000), which is a antithrombotic agent and a FXa inhibitor.

4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one Preparation Products And Raw materials

Raw materials

Preparation Products

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1252018-10-2, 4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-oneRelated Search:

Rivaroxaban Metabolite 8 (R)-5-chloro-N-(4-(3-oxomorpholino)phenyl)-N- ((2-oxooxazolidin-5-yl)methyl)thiophene-2-carboxamide Rivaroxaban Impurity 43 2-ThiophenecarboxaMide, 5-chloro-N,N-diMethyl- 1H-ISOINDOLE-1,3(2H)-DIONE, 2-[[(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-5-OXAZOLIDINYL]METHYL]- Rivaroxaban POLYSTYRENE IODOSOACETATE 1,2-Cyclohexanedione 4-(4-NITROPHENYL)MORPHOLIN-3-ONE (S)-(+)-Glycidyl Phthalimide (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one.HCl 5-CHLOROTHIOPHENE-2-CARBONYL CHLORIDE Ethyl (R)-(-)-4-cyano-3-hydroxybutyate 3-MORPHOLINONE, 4-[4-[(5S)-5-(AMINOMETHYL)-2-OXO-3-OXAZOLIDINYL]PHENYL]- 4-(4-AMINOPHENYL)MORPHOLIN-3-ONE 5-Chloro-2-thiophenecarboxylic Acid m-(Trifluoromethyl)phenylacetic acid (S)-(+)-Epichlorohydrin

(R)-4-[4-[(3-Chloro-2-hydroxypropyl)amino]phenyl]morpholin-3-one

4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-p ropyl)amino)phenyl]morpholin-3-one 2-[(2R)-2-hydroxy-3-{[4-(3-oxomorph olin-4-yl)phenyl]amino}propyl]-1H-is oindole-1,3(2H)-dione 2-[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpho linyl)phenyl]-5-oxazolidinyl]methyl]-1H-isoindole-1

3-Morpholinone, 4-[4-[[(2R)-3-chloro-2-hydroxypropyl]amino]phenyl]-

1252018-10-2,4-[4-(N-(3-CHLORO-(2R)-2-HYDROXY-1-PROPYL)AMINO)PHENYL]MORPHOLIN-3-ONE

4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one

Rivaroxaban Impurity 236

1252018-10-2