ML234

ChemicalBook > CAS DataBase List > ML234

Product Name: ML234
CAS No.: 1222800-79-4
Chemical Name: ML234
Synonyms: ML243;ML324;ML234;CS-2198;ML324, ML-324;5-Pyrroledione;NCGC00183808-01;ML234 USP/EP/BP;ML-324;ML324;ML 324;ML324(CID-44143209)
CBNumber: CB72744613
Molecular Formula: C21H23N3O2
Formula Weight: 349.43
MOL File: 1222800-79-4.mol

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ML234 Property

Melting point:: >187oC (dec.)
Boiling point:: 590.1±50.0 °C(Predicted)
Density: 1.188±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
solubility: DMSO: soluble10mg/mL, clear
form: powder
pka: 4.71±0.40(Predicted)
color: white to light brown
Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0741
Product name: ML324
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $85.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0741
Product name: ML324
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $430
Updated: 2024/03/01

Cayman Chemical

Product number: 17472
Product name: ML-324
Purity: ≥95%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 17472
Product name: ML-324
Purity: ≥95%
Packaging: 5mg
Price: $70
Updated: 2024/03/01

Cayman Chemical

Product number: 17472
Product name: ML-324
Purity: ≥95%
Packaging: 10mg
Price: $109
Updated: 2024/03/01

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ML234 Chemical Properties,Usage,Production

Description

ML324 (1222800-79-4) inhibits JMJD2 histone demethylases. Represses the expression of viral (HCMV and HSV-1) immediate early genes (IC50 ~ 10 μM) and abrogates infection. ML-324 represses the reactivation of HSV from the latent state in sensory neurons.1

Uses

ML324 is a JMJD2 demethylase inhibitor. It blocks the initiation of viral lytic infection and HSV-1 reactivation in the sensory ganglia of latently infected mice.

References

1) Liang?et al. (2013),?Targeting the JMJD2 histone demethylases to epigenetically control herpesvirus infection and reactivation from latency; Sci. Transl. Med.,?5?167ra5

ML234 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from ML234 manufacturers

Career Henan Chemical Co

Product: ML234 1222800-79-4
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 20kg
Release date: 2019-12-23

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ML234

ML324

ML243

N-[3-(Dimethylamino)propyl]-4-(8-hydroxy-6-quinolinyl)benzamide

NCGC00183808-01

ML324(CID-44143209)

CS-2198

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ML234 USP/EP/BP

5-Pyrroledione

ML324, ML-324

1222800-79-4

Inhibitors