ChemicalBook > CAS DataBase List > 2-Amino-5-iodopyridine

2-Amino-5-iodopyridine

Uses Uses Application

Product Name: 2-Amino-5-iodopyridine
CAS No.: 20511-12-0
Chemical Name: 2-Amino-5-iodopyridine
Synonyms: AKOS BB-8250;ASISCHEM U79390;BUTTPARK 153\33-57;5-iodo-2-pyridinamin;5-IODOPYRIDIN-2-AMINE;5-IODO-2-PYRIDINAMINE;2-AMINO-5-IODOPYRIDINE;5-Iodopyridine-2-amine;5-Iodo-2-aminopyridine;2-Amiao-5-iodopyridine
CBNumber: CB7281679
Molecular Formula: C5H5IN2
Formula Weight: 220.01
MOL File: 20511-12-0.mol

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2-Amino-5-iodopyridine Property

Melting point:: 128-131 °C (lit.)
Boiling point:: 293.8±25.0 °C(Predicted)
Density: 2.055±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), DMSO (Slightly)
pka: 4.91±0.13(Predicted)
form: Solid
color: Pale Yellow to Light Beige
Water Solubility: Insoluble
Sensitive: Light Sensitive
BRN: 108738
InChI: InChI=1S/C5H5IN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8)
InChIKey: IVILGUFRMDBUEQ-UHFFFAOYSA-N
SMILES: C1(N)=NC=C(I)C=C1
CAS DataBase Reference: 20511-12-0(CAS DataBase Reference)
EPA Substance Registry System: 2-Pyridinamine, 5-iodo- (20511-12-0)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-20/21/22
Safety Statements: 26-36-37/39
WGK Germany: 3
Hazard Note: Irritant
TSCA: Yes
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 516392
Product name: 2-Amino-5-iodopyridine
Purity: 98%
Packaging: 1g
Price: $43.83
Updated: 2025/07/31

TCI Chemical

Product number: A1842
Product name: 2-Amino-5-iodopyridine
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $27
Updated: 2025/07/31

TCI Chemical

Product number: A1842
Product name: 2-Amino-5-iodopyridine
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $78
Updated: 2025/07/31

TCI Chemical

Product number: A1842
Product name: 2-Amino-5-iodopyridine
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $234
Updated: 2025/07/31

Usbiological

Product number: A1378-29
Product name: 2-Amino-5-iodopyridine
Packaging: 250mg
Price: $312
Updated: 2021/12/16

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2-Amino-5-iodopyridine Chemical Properties,Usage,Production

Uses

2-Amino-5-iodopyridine is a compound that can be used in organic synthesis.

Uses

2-Amino-5-iodopyridine can be used as a chemical and pharmaceutical intermediate in laboratory research and development and chemical and pharmaceutical synthesis processes.

Application

2-Amino-5-iodopyridine, also known as 2-amino-5-iodopyridine or 5-iodo-2-aminopyridine, is an important intermediate in organic synthesis. It is mainly used as a pharmaceutical intermediate, and also in the production of dyes, pesticides, and fragrances.

Chemical Properties

Light yellow needles

Synthesis

504-29-0

20511-12-0

Example 20: Scheme C10 2-Aminopyridine (II) (1.0 eq, 318 mmol, 30.0 g), periodate dihydrate (0.15 eq, 48 mmol, 10.7 g), and iodine (0.42 eq, 134 mmol, 32.4 g) were dissolved in a mixture of acetic acid (800 mL), water (36 mL), and sulfuric acid (6.2 mL), and heated to react at 80°C for 4 for 4 hours. Upon completion of the reaction, the reaction mixture was poured into 10% Na2S2O3 aqueous solution to quench unreacted iodine and subsequently extracted with ether. The organic phases were combined, washed with 10% NaOH aqueous solution, dried over anhydrous MgSO4 and concentrated under reduced pressure. The crude product was purified by column chromatography (elution gradient: heptane/ethyl acetate 25:75 → pure ethyl acetate) to afford the target compound 2-amino-5-iodopyridine (116) (52.0 g, 74% yield). 1H NMR (δ, CDCl3): 4.51 (2H, s), 6.35 (1H, d, J = 8 Hz), 7.62 (1H, d, J = 8 Hz), 8.21 (1H, s).

References

[1] Journal of Heterocyclic Chemistry, 2017, vol. 54, # 5, p. 2656 - 2663
[2] European Journal of Medicinal Chemistry, 2010, vol. 45, # 3, p. 1211 - 1219
[3] Synthetic Communications, 2010, vol. 40, # 23, p. 3506 - 3513
[4] Synthetic Communications, 2013, vol. 43, # 21, p. 2913 - 2925
[5] Journal of the American Chemical Society, 2003, vol. 125, # 3, p. 616 - 617

2-Amino-5-iodopyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Amino-5-iodopyridine manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 2-Amino-5-iodopyridine 20511-12-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-05-30

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Amino-5-iodopyridine 20511-12-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-12

Henan Fengda Chemical Co., Ltd

Product: 5-Iodo-2-pyridinamine 20511-12-0
Price: US $8.00-0.80/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-01-22

20511-12-0, 2-Amino-5-iodopyridineRelated Search:

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ASISCHEM U79390

BUTTPARK 153\33-57

2-AMINO-5-IODOPYRIDINE

2-PYRIDINAMINE, 5-IODO-

5-IODOPYRIDIN-2-AMINE

5-iodopyridin-2-amine(SALTDATA: FREE)

2--5- aMinopyridine iodide

5-iodo-2-pyridinylamine

5-Iodo-2-aminopyridine

2-Amino-5-iodopyridine ,98%

5-Iodopyridine-2-amine

2-Amiao-5-iodopyridine

5-IODO-PYRIDIN-2-YLAMINE

5-IODO-2-PYRIDINAMINE

AKOS BB-8250

5-iodo-2-pyridinamin

2-Amino-5-iodopyridine 97%

JR-6750, 5-Iodopyridin-2-amine, 97%

2-Amino-5-iodopyridine&gt

2-Amino-5-iodopyridine ISO 9001：2015 REACH

2-Amino-5-Iodine Pyridine

2-Amino-5-iodiodipyridine

2-Amino-5-iodopyridine, 96%

20511-12-0

2051-12-0

C5H5IN

C5H5N2I

C5H5IN2

C5H6IN2

Pyridines

Halogenated Heterocycles

Heterocyclic Building Blocks

Building Blocks

Halopyridines

Iodopyridines

Pyridines derivates

Heterocyclic Compounds

Anilines, Amides & Amines

Iodine Compounds

Miscellaneous Compounds

Halopyridines

Iodopyridines

Heterocycles

C5Heterocyclic Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Pyridine

Amino-pyridine series

Amines

blocks

Iodides

Pyridines

Pyridine series

pyridine derivative

Pyridines, Pyrimidines, Purines and Pteredines