2-Amino-5-iodopyridine
Uses Uses Application- Product Name
- 2-Amino-5-iodopyridine
- CAS No.
- 20511-12-0
- Chemical Name
- 2-Amino-5-iodopyridine
- Synonyms
- AKOS BB-8250;ASISCHEM U79390;BUTTPARK 153\33-57;5-iodo-2-pyridinamin;5-IODOPYRIDIN-2-AMINE;5-IODO-2-PYRIDINAMINE;2-AMINO-5-IODOPYRIDINE;5-Iodopyridine-2-amine;5-Iodo-2-aminopyridine;2-Amiao-5-iodopyridine
- CBNumber
- CB7281679
- Molecular Formula
- C5H5IN2
- Formula Weight
- 220.01
- MOL File
- 20511-12-0.mol
2-Amino-5-iodopyridine Property
- Melting point:
- 128-131 °C (lit.)
- Boiling point:
- 293.8±25.0 °C(Predicted)
- Density
- 2.055±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), DMSO (Slightly)
- pka
- 4.91±0.13(Predicted)
- form
- Solid
- color
- Pale Yellow to Light Beige
- Water Solubility
- Insoluble
- Sensitive
- Light Sensitive
- BRN
- 108738
- InChI
- InChI=1S/C5H5IN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8)
- InChIKey
- IVILGUFRMDBUEQ-UHFFFAOYSA-N
- SMILES
- C1(N)=NC=C(I)C=C1
- CAS DataBase Reference
- 20511-12-0(CAS DataBase Reference)
- EPA Substance Registry System
- 2-Pyridinamine, 5-iodo- (20511-12-0)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- Hazard Note
- Irritant
- TSCA
- Yes
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 516392
- Product name
- 2-Amino-5-iodopyridine
- Purity
- 98%
- Packaging
- 1g
- Price
- $43.83
- Updated
- 2025/07/31
- Product number
- A1842
- Product name
- 2-Amino-5-iodopyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $27
- Updated
- 2025/07/31
- Product number
- A1842
- Product name
- 2-Amino-5-iodopyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $78
- Updated
- 2025/07/31
- Product number
- A1842
- Product name
- 2-Amino-5-iodopyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $234
- Updated
- 2025/07/31
- Product number
- A611720
- Product name
- 2-Amino-5-iodopyridine
- Packaging
- 2.5g
- Price
- $80
- Updated
- 2021/12/16
2-Amino-5-iodopyridine Chemical Properties,Usage,Production
Uses
2-Amino-5-iodopyridine is a compound that can be used in organic synthesis.
Uses
2-Amino-5-iodopyridine can be used as a chemical and pharmaceutical intermediate in laboratory research and development and chemical and pharmaceutical synthesis processes.
Application
2-Amino-5-iodopyridine, also known as 2-amino-5-iodopyridine or 5-iodo-2-aminopyridine, is an important intermediate in organic synthesis. It is mainly used as a pharmaceutical intermediate, and also in the production of dyes, pesticides, and fragrances.
Chemical Properties
Light yellow needles
Synthesis
504-29-0
20511-12-0
Example 20: Scheme C10 2-Aminopyridine (II) (1.0 eq, 318 mmol, 30.0 g), periodate dihydrate (0.15 eq, 48 mmol, 10.7 g), and iodine (0.42 eq, 134 mmol, 32.4 g) were dissolved in a mixture of acetic acid (800 mL), water (36 mL), and sulfuric acid (6.2 mL), and heated to react at 80°C for 4 for 4 hours. Upon completion of the reaction, the reaction mixture was poured into 10% Na2S2O3 aqueous solution to quench unreacted iodine and subsequently extracted with ether. The organic phases were combined, washed with 10% NaOH aqueous solution, dried over anhydrous MgSO4 and concentrated under reduced pressure. The crude product was purified by column chromatography (elution gradient: heptane/ethyl acetate 25:75 → pure ethyl acetate) to afford the target compound 2-amino-5-iodopyridine (116) (52.0 g, 74% yield). 1H NMR (δ, CDCl3): 4.51 (2H, s), 6.35 (1H, d, J = 8 Hz), 7.62 (1H, d, J = 8 Hz), 8.21 (1H, s).
References
[1] Journal of Heterocyclic Chemistry, 2017, vol. 54, # 5, p. 2656 - 2663
[2] European Journal of Medicinal Chemistry, 2010, vol. 45, # 3, p. 1211 - 1219
[3] Synthetic Communications, 2010, vol. 40, # 23, p. 3506 - 3513
[4] Synthetic Communications, 2013, vol. 43, # 21, p. 2913 - 2925
[5] Journal of the American Chemical Society, 2003, vol. 125, # 3, p. 616 - 617
2-Amino-5-iodopyridine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Amino-5-iodopyridine Suppliers
- Tel
- --
- Fax
- --
- Country
- France
- ProdList
- 303
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@borochem.fr
- Country
- France
- ProdList
- 852
- Advantage
- 46
- Tel
- --
- Fax
- --
- interchim@interchim.com
- Country
- France
- ProdList
- 6302
- Advantage
- 76
View Lastest Price from 2-Amino-5-iodopyridine manufacturers
- Product
- 2-Amino-5-iodopyridine 20511-12-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-30
- Product
- 2-Amino-5-iodopyridine 20511-12-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-12
- Product
- 5-Iodo-2-pyridinamine 20511-12-0
- Price
- US $8.00-0.80/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-01-22