5-Bromo-2-iodopyrimidine

Product Name: 5-Bromo-2-iodopyrimidine
CAS No.: 183438-24-6
Chemical Name: 5-Bromo-2-iodopyrimidine
Synonyms: 2-broMo-5-iodopyriMidine;5-Bromo-2-iod;5-bromo-2-iodimidine;5-Brom-2-iodpyrimidin;5-Bromo-iodopyrimidine;5-bromo-2-iodopyrimine;5-Brmo-2-iodopyrimidine;5-BROMO-2-IODOPYRIMIDINE;5-Bromo-2-iodo-1,3-diazine;Pyrimidine, 5-bromo-2-iodo-
CBNumber: CB7281811
Molecular Formula: C4H2BrIN2
Formula Weight: 284.88
MOL File: 183438-24-6.mol

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5-Bromo-2-iodopyrimidine Property

Melting point:: 99-103 °C (lit.)
Boiling point:: 341.0±34.0 °C(Predicted)
Density: 2.495±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: -2.56±0.22(Predicted)
form: Crystalline Powder
color: White to tan
Sensitive: Light Sensitive
InChI: InChI=1S/C4H2BrIN2/c5-3-1-7-4(6)8-2-3/h1-2H
InChIKey: ZEZKXPQIDURFKA-UHFFFAOYSA-N
SMILES: C1(I)=NC=C(Br)C=N1
CAS DataBase Reference: 183438-24-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/38-36/37/38
Safety Statements: 26-37/39-37
WGK Germany: 3
HazardClass: IRRITANT, LIGHT SENSITIVE
HS Code: 29309090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 637750
Product name: 5-Bromo-2-iodopyrimidine
Purity: 97%
Packaging: 1g
Price: $46.47
Updated: 2025/07/31

TRC

Product number: B683740
Product name: 5-Bromo-2-iodopyrimidine
Packaging: 5g
Price: $195
Updated: 2021/12/16

TRC

Product number: B683740
Product name: 5-Bromo-2-iodopyrimidine
Packaging: 25g
Price: $635
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB11951
Product name: 5-Bromo-2-iodopyrimidine
Packaging: 500g
Price: $650
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK335944
Product name: 2-Iodo-5-bromopyrimidine
Purity: 98%
Packaging: 1g
Price: $195
Updated: 2021/12/16

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5-Bromo-2-iodopyrimidine Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

5-Bromo-2-iodopyrimidine can be used to synthesize 5,5′-dibromo-2,2′-bipyrimidine and O,O′-dimethyl hyrtinadine A.

General Description

5-Bromo-2-iodopyrimidine can be synthesized by reacting 5-bromo-2-chloropyrimidine with hydroiodic acid.

Synthesis

32779-36-5

183438-24-6

General procedure for the synthesis of 5-bromo-2-iodopyrimidine from 5-bromo-2-chloropyrimidine: 5-bromo-2-chloropyrimidine (5.80 g, 30 mmol) and sodium iodide (7.5 g, 50 mmol) were suspended in chloroform (20 mL), and hydriodic acid (57 wt%, 2.85 g, 25.6 mmol) was slowly added at 0 °C. After cooling was withdrawn, the reaction mixture was stirred at room temperature for 20 hours. Subsequently, the reaction mixture was poured into a mixture of 200 mL of ice water with 30 mL of 10 N sodium hydroxide solution. Chloroform (150 mL) was added and stirred for 10 minutes. The organic phase was separated and the aqueous layer was extracted with chloroform (2 x 100 mL). The organic phases were combined, dried over anhydrous magnesium sulfate, and concentrated in vacuo to give 5-bromo-2-iodopyrimidine as a light yellow solid. Yield: 6.29 g (84%). Mass spectrum (MS): M = 284.8 (ESI+). 1H-NMR (300 MHz, CDCl3): δ 8.54 (s, 2H), 7.56 (d, J = 16.4 Hz, 1H), 7.59-7.66 (m, 4H).

References

[1] Angewandte Chemie - International Edition, 1999, vol. 38, # 5, p. 659 - 661
[2] Patent: US2005/222228, 2005, A1. Location in patent: Page/Page column 15-16
[3] Chemical Communications, 1996, # 24, p. 2719 - 2720
[4] Patent: US2012/238751, 2012, A1. Location in patent: Page/Page column 30
[5] Patent: WO2014/43272, 2014, A1. Location in patent: Paragraph 0411; 0412; 0413

5-Bromo-2-iodopyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Bromo-2-iodopyrimidine Suppliers

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View Lastest Price from 5-Bromo-2-iodopyrimidine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 5-Bromo-2-iodopyrimidine 183438-24-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-22

Hebei Chuanghai Biotechnology Co., Ltd

Product: 5-Bromo-2-iodopyrimidine 183438-24-6
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-29

Henan Aochuang Chemical Co.,Ltd.

Product: 5-Bromo-2-iodopyrimidine 183438-24-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-27

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5-BROMO-2-IODOPYRIMIDINE

2-broMo-5-iodopyriMidine

5-Bromo-iodopyrimidine

5-Brmo-2-iodopyrimidine

5-bromo-2-iodopyrimine

5-BroMo-2-iodopyriMidine (This product is unavailable in the U.S.)

5-Bromo-2-iodo-1,3-diazine

5-<WBR>BroMo-<WBR>2-<WBR>iodopyriMidine

5-Bromo-2-iod

5-Bromo-2-iodopyrimidine (This product is unavailable in the U.S.)&gt

Pyrimidine, 5-bromo-2-iodo-

5-Bromo-2-iodopyrimidine ISO 9001：2015 REACH

5-Brom-2-iodpyrimidin

5-bromo-2-iodimidine

5-Bromo-2-iodopyrimidine, 99%

183438-24-6

83438-24-6

138438-24-6

Building Blocks

Heterocyclic Building Blocks

Halogenated Heterocycles

Pyrimidines

Pyridines, Pyrimidines, Purines and Pteredines

Pyrazines, Pyrimidines & Pyridazines

Pyrimidine

Pyrazines, Pyrimidines & Pyridazines

Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Pyrimidines

PyrimidinesHeterocyclic Building Blocks

Pyrimidine Series

Halides

Heterocycles

Heterocycle-Pyrimidine series