2,5-Bis(trifluoromethyl)nitrobenzene

Product Name: 2,5-Bis(trifluoromethyl)nitrobenzene
CAS No.: 320-88-7
Chemical Name: 2,5-Bis(trifluoromethyl)nitrobenzene
Synonyms: 2,5-DI(TRIFLUOROMETHYL)NITROBENZENE;2,5-BIS(TRIFLUOROMETHYL)NITROBENZENE;2-NITRO-1,4-BIS(TRIFLUOROMETHYL)BENZENE;1-NITRO-2,5-BIS(TRIFLUOROMETHYL)BENZENE;1,4-BIS(TRIFLUOROMETHYL)-2-NITROBENZENE;2,5-Bis(trifluoromethyl)nitrobenzene97%;2,5-Bis(trifluoromethyl)nitrobenzene 97%;Benzene, 2-nitro-1,4-bis(trifluoromethyl)-;1-Nitro-2,5-bis(trifluoromethyl)benzene>2-Nitro-1,4-bis(trifluoromethyl)benzene,98%
CBNumber: CB7281886
Molecular Formula: C8H3F6NO2
Formula Weight: 259.11
MOL File: 320-88-7.mol

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2,5-Bis(trifluoromethyl)nitrobenzene Property

Boiling point:: 70-75 °C (15 mmHg)
Density: 1.57
refractive index: 1.4235-1.4255
Flash point:: 77 °C
storage temp.: 2-8°C
solubility: Chloroform, Methanol
form: Liquid
color: Pale yellow to yellow
Sensitive: Light Sensitive
CAS DataBase Reference: 320-88-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,T
Risk Statements: 36/37/38
Safety Statements: 37/39-26-60-37-23
HazardClass: TOXIC
HS Code: 29049090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: B2546
Product name: 1-Nitro-2,5-bis(trifluoromethyl)benzene
Purity: >98.0%(GC)
Packaging: 5g
Price: $26
Updated: 2025/07/31

TCI Chemical

Product number: B2546
Product name: 1-Nitro-2,5-bis(trifluoromethyl)benzene
Purity: >98.0%(GC)
Packaging: 25g
Price: $78
Updated: 2025/07/31

TRC

Product number: B591783
Product name: 2,5-Bis(Trifluoromethyl)nitrobenzene
Packaging: 250mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 005832
Product name: 2,5-Bis(trifluoromethyl)nitrobenzene
Purity: 97%
Packaging: 5g
Price: $14
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4854-3-08
Product name: 2,5-Bis(trifluoromethyl)nitrobenzene
Purity: 97%
Packaging: 1g
Price: $20
Updated: 2021/12/16

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2,5-Bis(trifluoromethyl)nitrobenzene Chemical Properties,Usage,Production

Chemical Properties

clear yellow liquid

Uses

2,5-Bis(Trifluoromethyl)nitrobenzene can be prepared to be used as antifungal agents.

Synthesis

433-19-2

320-88-7

General Steps: Example 2: Using 2,3-difluorotoluene as raw material, adopting the same reaction conditions as in Example 1, but replacing 96 mass% sulfuric acid with fuming sulfuric acid with a sulfur trioxide concentration of 10 mass%, the reaction was stirred at 80° C. for 8 hours to obtain 2,5-bis(trifluoromethyl)nitrobenzene in a yield of 68.7%. Example 4: Using 2,3-difluorotoluene as raw material, the same reaction conditions as in Example 1 were used, but 96 mass% of sulfuric acid was replaced with fuming sulfuric acid having a sulfur trioxide concentration of 10 mass%, and 97 mass% of fuming nitric acid was replaced with 98 mass% of concentrated nitric acid, and the reaction was stirred at 80°C for 10 hours to obtain 2,5-bis(trifluoromethyl)nitrobenzene in a yield of 65.3%. Example 7 (Comparative Example): Using 2,3-difluorotoluene as raw material and the same reaction conditions as in Example 1, but replacing 96 mass% sulfuric acid with fuming sulfuric acid with a sulfur trioxide concentration of 24 mass%, 2,5-bis(trifluoromethyl)nitrobenzene was obtained in a yield of 32.5%.

References

[1] Patent: EP1468983, 2004, A1. Location in patent: Page 6
[2] Patent: EP1468983, 2004, A1. Location in patent: Page 5; 6
[3] Journal of the American Chemical Society, 1953, vol. 75, p. 4967
[4] Journal of Organic Chemistry, 1995, vol. 60, # 22, p. 7348 - 7350
[5] Patent: WO2011/150156, 2011, A2. Location in patent: Page/Page column 132

2,5-Bis(trifluoromethyl)nitrobenzene Preparation Products And Raw materials

Raw materials

Preparation Products

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2,5-Bis(trifluoromethyl)nitrobenzene Suppliers

Americas 1 Belgium 2 China 78 Europe 3 France 2 Germany 6 India 5 Italy 1 Japan 1 Switzerland 1 The Netherlands 1 United Kingdom 11 United States 36 Global 148

J & K SCIENTIFIC LTD.

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View Lastest Price from 2,5-Bis(trifluoromethyl)nitrobenzene manufacturers

Career Henan Chemical Co

Product: 2,5-Bis(trifluoromethyl)nitrobenzene 320-88-7
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 10000KGS
Release date: 2020-01-09

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2-Nitro-1,4-bis(trifluoromethyl)benzene CAS：320-88-7

320-88-7

C6H3F6NO2

C8H3NO2F6