Propargyl-PEG5-t-butyl ester
- Product Name
- Propargyl-PEG5-t-butyl ester
- CAS No.
- 1245823-50-0
- Chemical Name
- Propargyl-PEG5-t-butyl ester
- Synonyms
- Propargyl-PEG5-COOtBu;PropargylPEG5-tBu ester;Propargyl-PEG4-C2-COOtBu;Alkyne-PEG5-CH2CH2COOtBu;Propargyl-PEG4-CH2CH2-Boc;PROPARGYL-PEG5-CH2CH2COOTBU;Propargyl-PEG5-t-butyl ester;1-Boc-3,6,9,12,15-pentaoxaoctadec-17-yne;tert-butyl 4,7,10,13,16-pentaoxanonadec-18-ynoate;4,7,10,13,16-Pentaoxanonadec-18-ynoic acid, 1,1-dimethylethyl ester
- CBNumber
- CB73048734
- Molecular Formula
- C18H32O7
- Formula Weight
- 360.44
- MOL File
- 1245823-50-0.mol
Propargyl-PEG5-t-butyl ester Property
- Boiling point:
- 420.6±40.0 °C(Predicted)
- Density
- 1.045±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- P839468
- Product name
- Propargyl-PEG5-t-butylEster
- Packaging
- 100mg
- Price
- $330
- Updated
- 2021/12/16
- Product number
- BP-20651
- Product name
- Propargyl-PEG5-t-butylester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $230
- Updated
- 2021/12/16
- Product number
- AS107878
- Product name
- Propargyl-PEG5-CH2CH2COOtBu
- Purity
- 97%
- Packaging
- 250mg
- Price
- $310
- Updated
- 2021/12/16
- Product number
- BIPG1746
- Product name
- Propargyl-PEG5-t-butylester
- Packaging
- 250mg
- Price
- $482
- Updated
- 2021/12/16
- Product number
- B-1477
- Product name
- Propargyl-PEG4-CH2CH2COOtBu
- Purity
- 97%
- Packaging
- 0.5g
- Price
- $256.67
- Updated
- 2021/12/16
Propargyl-PEG5-t-butyl ester Chemical Properties,Usage,Production
Description
Propargyl-PEG5-t-butyl ester has one of the functional groups protected by t-butyl group. The protection can be removed under acidic conditions. The propargyl group forms triazole linkages with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry. The PEG units help improving the water-solubility of the molecule in aqueous media.
Uses
Propargyl-PEG4-CH2CH2-Boc is a non-cleavable ADC linker that can be used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG4-CH2CH2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
Non-cleavable Linker; Alkyl/ether
References
[1] Zhang H, et al. Thiodigalactoside-Bovine Serum Albumin Conjugates as High-Potency Inhibitors of Galectin-3: An Outstanding Example of Multivalent Presentation of Small Molecule Inhibitors. Bioconjug Chem. 2018 Apr 18;29(4):1266-1275. DOI:10.1021/acs.bioconjchem.8b00047
Propargyl-PEG5-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Propargyl-PEG5-t-butyl ester Suppliers
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- +1-781-999-5354; +17819995354
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- Country
- United States
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- sales@medchemexpress.com
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- United States
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View Lastest Price from Propargyl-PEG5-t-butyl ester manufacturers
- Product
- Propargyl-PEG5-COOtBu 1245823-50-0
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-26