(R)-1-Boc-3-Aminopiperidine

Product Name: (R)-1-Boc-3-Aminopiperidine
CAS No.: 188111-79-7
Chemical Name: (R)-1-Boc-3-Aminopiperidine
Synonyms: tert-butyl (R)-3-aminopiperidine-1-carboxylate;(R)-TERT-BUTYL 3-AMINOPIPERIDINE-1-CARBOXYLATE;tert-Butyl (3R)-3-aminopiperidine-1-carboxylate;(R)-3-AMINO-1-N-BOC-PIPERIDINE;LigliptinImpurity69;(R)-BOC-PIP(3-NH2) HCL;Linagliptin Impurity 69;Linagliptin Impurity 98;(R)-1-BOC-3-PIPERIDINAMINE;(R)-1-Boc-3-AMinopiperidin
CBNumber: CB7326716
Molecular Formula: C10H20N2O2
Formula Weight: 200.28
MOL File: 188111-79-7.mol

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(R)-1-Boc-3-Aminopiperidine Property

alpha: 28.5 º (c=1, DMF)
Boiling point:: 277.3±33.0 °C(Predicted)
Density: 1.041±0.06 g/cm3(Predicted)
refractive index: 1.4730
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
solubility: Chloroform (Slightly), DMF (Slightly), DMSO (Slightly)
pka: 10.35±0.20(Predicted)
form: Liquid
color: Colorless to pale yellow
optical activity: [α]/D -28.5±2°, c = 1 in DMF
Water Solubility: Immiscible with water.
Sensitive: Moisture Sensitive
InChI: InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1
InChIKey: AKQXKEBCONUWCL-MRVPVSSYSA-N
SMILES: N1(C(OC(C)(C)C)=O)CCC[C@@H](N)C1
CAS DataBase Reference: 188111-79-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 26
RIDADR: UN2735
WGK Germany: 3
F: 10-34
HazardClass: 8
PackingGroup: III
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 07858
Product name: (R)-(−)-3-Amino-1-Boc-piperidine
Purity: ≥98.0% (TLC)
Packaging: 1G-F
Price: $283
Updated: 2024/03/01

Sigma-Aldrich

Product number: 07858
Product name: (R)-(−)-3-Amino-1-Boc-piperidine
Purity: ≥98.0% (TLC)
Packaging: 1g
Price: $272
Updated: 2023/01/07

Alfa Aesar

Product number: H26937
Product name: (R)-(-)-3-Amino-1-Boc-piperidine, 98%
Packaging: 5g
Price: $392.65
Updated: 2024/03/01

TRC

Product number: B692215
Product name: tert-Butyl(R)-3-Aminopiperidine-1-carboxylate
Packaging: 1g
Price: $150
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA10567
Product name: (3R)-3-Amino-N1-Boc-piperidine
Packaging: 25g
Price: $200
Updated: 2021/12/16

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(R)-1-Boc-3-Aminopiperidine Chemical Properties,Usage,Production

Chemical Properties

Yellow liquid

Uses

(R)-3-Amino-1-Boc-piperidine can be used to prepare a benzoxazepine derivative named (R)-7-(3,5-dimethoxyphenyl)-N-(piperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, a potent CBP/P300 bromodomain inhibitor.

Uses

(R)-(-)-3-Amino-1-Boc-piperidine(tert-Butyl (R)-3-Aminopiperidine-1-carboxylate), is an heterocyclic building block used for the synthesis of more complex pharmaceutical compounds. It is also found to act as a γ-secretase modulators, and a potent structure for lowering Ab42 production in both in vitro and in vivo.

General Description

(R)-3-Amino-1-Boc-piperidine can be used as a precursor for the preparation of dipeptidyl peptidase IV inhibitors like linagliptin, alogliptin, and other antidiabetic agents.

(R)-1-Boc-3-Aminopiperidine Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-1-Boc-3-Aminopiperidine Suppliers

Canada 1 China 296 Europe 3 France 2 Germany 8 India 6 Japan 3 Switzerland 2 United Kingdom 16 United States 60 Global 397

Chengdu Firster Pharmaceutical Co., Ltd.

Tel: 028-87078428 028-87074958
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Chengdu Aminotp Pharmaceutical Technology Co.,Ltd.

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Shanghai Boyle Chemical Co., Ltd.

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Alfa Aesar

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ShangHai DEMO Chemical Co.,Ltd

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Beijing HwrkChemical Technology Co., Ltd

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View Lastest Price from (R)-1-Boc-3-Aminopiperidine manufacturers

Xingtai Haoxun Import and Export Trade Co., Ltd.

Product: (R)-1-Boc-3-Aminopiperidine 188111-79-7
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10tons
Release date: 2020-07-17

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: (R)-1-Boc-3-Aminopiperidine 188111-79-7
Price: US $100.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2021-09-14

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: tert-butyl (3R)-3-aminopiperidine-1-carboxylate 188111-79-7
Price: US $100.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 10KG
Release date: 2021-09-17

188111-79-7, (R)-1-Boc-3-AminopiperidineRelated Search:

Glycine Haloperidol 3-AMINOPIPERIDINE tert-Butyl carbazate N-Carbobenzyloxyglycine tert-Butanol 6-Aminocaproic acid ALTRENOGEST Tris(hydroxymethyl)aminomethane 8-Bromo-3-methyl-xanthine 2-Aminoacetophenone (R)-Boc-Nipecotic acid Diphenoxylate 1-Piperidinecarboxylic acid, 3-[[(phenylmethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester, (3R)- 1,1'-Diacetylferrocene (R)-1-Boc-3-Aminopiperidine-3-carboxylic acid (R)-1-N-BOC-3-METHYLAMINO PIPERIDINE Piperidine

tert-Butyl (3R)-3-aminopiperidine-1-carboxylate

(R)-3-Aminopiperidine, N1-BOC protected

(R)-1-t-Butyloxycarbonyl-3-aminopiperidine hydrochloride

(R)-1-Boc-3-piperidinamine, tert-Butyl (R)-3-amino-1-piperidinecarboxylate

(R)-3-Amino-1-N-Boc-Piperidine (R)-1-Boc-3-Aminopiperidine

1-TERT-BUTYLOXYCARBONYL-3-R-AMINOPIPERIDINE HYDROCHLORIDE

1-Piperidinecarboxylicacid,3-amino-,1,1-dimethylethylester,(3R)-(9CI)

(R)-3-AMINO-N-BOC-PIPERIDINE

(R)-3-AMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

(R)-3-AMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER HCL

(R)-1-TERT-BUTYLOXYCARBONYL-3-AMINOPIPERIDINE HYDROCHLORIDE

(R)-1-BOC-3-PIPERIDINAMINE

(R)-1-BOC-3-AMNIOPIPERIDINE

(R)-1-BOC-3-AMINOPIPERIDINE

(R)-1-BOC-3-AMINOPIPERIDINE HCL

(R)-1-N-BOC-3-AMINO PIPERIDINE

(R)-N-BOC-3-AMINOPIPERIDINE

(R)-TERT-BUTYL 3-AMINOPIPERIDINE-1-CARBOXYLATE

TERT-BUTYL (R)-3-AMINO-1-PIPERIDINECARBOXYLATE

2-Methyl-2-propanyl (3S)-3-amino-1-piperidinecarboxylate

(3R)-3-Aminopiperidine, N1-BOC protected

(3R)-3-Amino-N1-Boc-piperidine

(R)-1-Boc-3-aMinopiperidi...

(R)-1-Boc-3-AMinopiperidin

tert-Butyl (3R)-3-aminopiperidine-1-carboxylate, (3R)-3-Amino-1-(tert-butoxycarbonyl)piperidine

(R)-1-Boc-3-AMniopiperidine SynonyMs (R)-3-AMino-1-N-Boc-piperidine

(R)-tert-Butyl 3-aMinopiperidine-1-carboxylate, >95%

(R)-(-)-3-Amino-1-Boc-piperidine,98%

tert-butyl (R)-3-aminopiperidine-1-carboxylate

(R)-1-Boc-3-aminopiperidine,99%e.e.

1-T-BUTYLOXYCARBONYL-3-R-AMINOPIPERIDINE HYDROCHLORIDE

1-tert-butyloxycarbonyl-3-r-aminopiperidine

1-PIPERIDINECARBOXYLIC ACID, 3-AMINO-, 1,1-DIMETHYLETHYL ESTER, (3R)-

(R)-BOC-PIP(3-NH2) HCL

(R)-3-AMINO-1-N-BOC-PIPERIDINE

(R)-3-AMINO-1-BOC-PIPERIDINE

(R)-3-AMINO-1-BOC-PIPERIDINE HYDROCHLORIDE

(R)-1-tert-butoxycarbonyl-3-aminoperidol

3-aminopiperidine-1-carboxyL

Linagliptin Impurity 69

Linagliptin N-t-BOC Piperidine Impurity

Linagliptin Impurity 98

(R)-3-aminopiperidine-1-carboxylate

ert-butyl(3R)-3-aminopiperidine-1-carboxylate

(R)-1-Boc-3-Aminopiperidine USP/EP/BP

LigliptinImpurity69

(R)-tert-Butyl 3-amino-piperidin-1-carboxylate

188111-79-7

1152113-32-0

1118-90-1

C10H21ClN2O2

CHIRAL CHEMICALS

Piperidines

Piperidine Series

pharmacetical

Piperidine

AMINOACID