ChemicalBook > CAS DataBase List > (R)-1-Boc-3-Aminopiperidine

(R)-1-Boc-3-Aminopiperidine

Product Name
(R)-1-Boc-3-Aminopiperidine
CAS No.
188111-79-7
Chemical Name
(R)-1-Boc-3-Aminopiperidine
Synonyms
tert-butyl (R)-3-aminopiperidine-1-carboxylate;(R)-TERT-BUTYL 3-AMINOPIPERIDINE-1-CARBOXYLATE;tert-Butyl (3R)-3-aminopiperidine-1-carboxylate;(R)-3-AMINO-1-N-BOC-PIPERIDINE;LigliptinImpurity69;(R)-BOC-PIP(3-NH2) HCL;Linagliptin Impurity 69;Linagliptin Impurity 98;(R)-1-BOC-3-PIPERIDINAMINE;(R)-1-Boc-3-AMinopiperidin
CBNumber
CB7326716
Molecular Formula
C10H20N2O2
Formula Weight
200.28
MOL File
188111-79-7.mol
More
Less

(R)-1-Boc-3-Aminopiperidine Property

alpha 
28.5 º (c=1, DMF)
Boiling point:
277.3±33.0 °C(Predicted)
Density 
1.041±0.06 g/cm3(Predicted)
refractive index 
1.4730
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
Chloroform (Slightly), DMF (Slightly), DMSO (Slightly)
pka
10.35±0.20(Predicted)
form 
Liquid
color 
Colorless to pale yellow
optical activity
[α]/D -28.5±2°, c = 1 in DMF
Water Solubility 
Immiscible with water.
Sensitive 
Moisture Sensitive
InChI
InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1
InChIKey
AKQXKEBCONUWCL-MRVPVSSYSA-N
SMILES
N1(C(OC(C)(C)C)=O)CCC[C@@H](N)C1
CAS DataBase Reference
188111-79-7(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26
RIDADR 
UN2735
WGK Germany 
3
F 
10-34
HazardClass 
8
PackingGroup 
III
HS Code 
29333990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
07858
Product name
(R)-(−)-3-Amino-1-Boc-piperidine
Purity
≥98.0% (TLC)
Packaging
1G-F
Price
$283
Updated
2024/03/01
Sigma-Aldrich
Product number
07858
Product name
(R)-(−)-3-Amino-1-Boc-piperidine
Purity
≥98.0% (TLC)
Packaging
1g
Price
$272
Updated
2023/01/07
Alfa Aesar
Product number
H26937
Product name
(R)-(-)-3-Amino-1-Boc-piperidine, 98%
Packaging
5g
Price
$392.65
Updated
2024/03/01
TRC
Product number
B692215
Product name
tert-Butyl(R)-3-Aminopiperidine-1-carboxylate
Packaging
1g
Price
$150
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA10567
Product name
(3R)-3-Amino-N1-Boc-piperidine
Packaging
25g
Price
$200
Updated
2021/12/16
More
Less

(R)-1-Boc-3-Aminopiperidine Chemical Properties,Usage,Production

Chemical Properties

Yellow liquid

Uses

(R)-3-Amino-1-Boc-piperidine can be used to prepare a benzoxazepine derivative named (R)-7-(3,5-dimethoxyphenyl)-N-(piperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, a potent CBP/P300 bromodomain inhibitor.

Uses

(R)-(-)-3-Amino-1-Boc-piperidine(tert-Butyl (R)-3-Aminopiperidine-1-carboxylate), is an heterocyclic building block used for the synthesis of more complex pharmaceutical compounds. It is also found to act as a γ-secretase modulators, and a potent structure for lowering Ab42 production in both in vitro and in vivo.

General Description

(R)-3-Amino-1-Boc-piperidine can be used as a precursor for the preparation of dipeptidyl peptidase IV inhibitors like linagliptin, alogliptin, and other antidiabetic agents.

(R)-1-Boc-3-Aminopiperidine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(R)-1-Boc-3-Aminopiperidine Suppliers

Canada 1 China 296 Europe 3 France 2 Germany 8 India 6 Japan 3 Switzerland 2 United Kingdom 16 United States 60 Global 397
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Accela ChemBio Inc.
Tel
+1(858) 699-3322
Fax
+1(858) 876-1948
Email
marketing@accelachem.com
Country
United States
ProdList
6024
Advantage
65
Alfa Chemistry
Tel
1-516-6625404
Fax
1-516-927-0118
Email
support@alfa-chemistry.com
Country
United States
ProdList
9171
Advantage
60
Accela ChemBio Inc.
Tel
+1-858-6993322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
17322
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81215950 4000-868-328
Email
customer@uwalab.com
Country
United States
ProdList
10404
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
AB PharmaTech,LLC
Tel
323-480-4688
Fax
323-480-4688
Email
sales@acrospharmatech.com
Country
United States
ProdList
989
Advantage
55
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Aceschem Inc.
Tel
+1-817863-6948 +1-（817）863-6948
Email
sales@aceschem.com
Country
United States
ProdList
19632
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
Anisyn, Inc.
Tel
--
Fax
--
Email
sales@anisyn.com
Country
United States
ProdList
863
Advantage
0
Chemphtec Corporation
Tel
--
Fax
--
Email
fo@chemphtec.com
Country
United States
ProdList
2181
Advantage
58
Chem-Impex International, Inc. (CII)
Tel
--
Fax
--
Email
Customer@chemimpex.com
Country
United States
ProdList
893
Advantage
58
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
Interchem Corporation USA
Tel
--
Fax
--
Email
esa@interchem.com
Country
United States
ProdList
469
Advantage
58
Brightek LLC
Tel
--
Fax
--
Country
United States
ProdList
782
Advantage
58
OChem Incorporation
Tel
--
Fax
--
Email
sales@ocheminc.com
Country
United States
ProdList
6501
Advantage
60
VWR International, LLC.
Tel
--
Fax
--
Email
@sargentwelch.com
Country
United States
ProdList
6262
Advantage
58
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Synthonix
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
1423
Advantage
68
Ivy Fine Chemicals
Tel
--
Fax
--
Email
sales@ivychem.com
Country
United States
ProdList
6493
Advantage
58
RnD SciChem, LLC
Tel
--
Fax
--
Email
rndscichem@gmail.com
Country
United States
ProdList
569
Advantage
0
Allweys LLC
Tel
--
Fax
--
Email
sales@allweysllc.com
Country
United States
ProdList
690
Advantage
30
Small Molecules, Inc.
Tel
--
Fax
--
Email
sales@small-molecules.com
Country
United States
ProdList
990
Advantage
50
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
HDH Pharma, Inc.
Tel
--
Fax
--
Email
catalog@hdhpharma.com
Country
United States
ProdList
6248
Advantage
62
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
AlliChem, LLC
Tel
--
Fax
--
Email
sales@allichemllc.com
Country
United States
ProdList
6516
Advantage
60
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
Magical Scientific LLC
Tel
--
Fax
--
Country
United States
ProdList
703
Advantage
0
ECA International Corporation
Tel
--
Fax
--
Email
services@ecacorporation.com
Country
United States
ProdList
1062
Advantage
52
Rintech, Inc.
Tel
--
Fax
--
Email
info@rintechinc.com
Country
United States
ProdList
3416
Advantage
60
CNH Technologies, Inc.
Tel
--
Fax
--
Email
info@cnhtechnologies.com
Country
United States
ProdList
353
Advantage
42
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
Aagile Labs Division of Tyger Scientific
Tel
--
Fax
--
Email
tygersci@yahoo.com
Country
United States
ProdList
6568
Advantage
68
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
D-L Chiral Chemicals, LLC
Tel
--
Fax
--
Country
United States
ProdList
977
Advantage
42
Beta Pharma, Inc.
Tel
--
Fax
--
Email
sales@betapharma.com
Country
United States
ProdList
6226
Advantage
60
AstaTech, Inc
Tel
--
Fax
--
Email
sales@astatechinc.com
Country
United States
ProdList
6371
Advantage
58
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
Bio-Vin Research Laboratories
Tel
--
Fax
--
Email
sales@biovinresearch.com
Country
United States
ProdList
6210
Advantage
64
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
AQCHEM, LLC
Tel
--
Fax
--
Email
sales@aqchem.com
Country
United States
ProdList
491
Advantage
43
Small Molecules, Inc.
Tel
--
Fax
--
Email
sales@small-molecules.com
Country
United States
ProdList
1218
Advantage
30
More
Less

View Lastest Price from (R)-1-Boc-3-Aminopiperidine manufacturers

Xingtai Haoxun Import and Export Trade Co., Ltd.
Product
(R)-1-Boc-3-Aminopiperidine 188111-79-7
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10tons
Release date
2020-07-17
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
(R)-1-Boc-3-Aminopiperidine 188111-79-7
Price
US $100.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2021-09-14
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
tert-butyl (3R)-3-aminopiperidine-1-carboxylate 188111-79-7
Price
US $100.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10KG
Release date
2021-09-17

188111-79-7, (R)-1-Boc-3-AminopiperidineRelated Search:

Glycine Haloperidol 3-AMINOPIPERIDINE tert-Butyl carbazate N-Carbobenzyloxyglycine tert-Butanol 6-Aminocaproic acid ALTRENOGEST Tris(hydroxymethyl)aminomethane 8-Bromo-3-methyl-xanthine 2-Aminoacetophenone (R)-Boc-Nipecotic acid Diphenoxylate 1-Piperidinecarboxylic acid, 3-[[(phenylmethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester, (3R)- 1,1'-Diacetylferrocene (R)-1-Boc-3-Aminopiperidine-3-carboxylic acid (R)-1-N-BOC-3-METHYLAMINO PIPERIDINE Piperidine

  • tert-Butyl (3R)-3-aminopiperidine-1-carboxylate
  • (R)-3-Aminopiperidine, N1-BOC protected
  • (R)-1-t-Butyloxycarbonyl-3-aminopiperidine hydrochloride
  • (R)-1-Boc-3-piperidinamine, tert-Butyl (R)-3-amino-1-piperidinecarboxylate
  • (R)-3-Amino-1-N-Boc-Piperidine (R)-1-Boc-3-Aminopiperidine
  • 1-TERT-BUTYLOXYCARBONYL-3-R-AMINOPIPERIDINE HYDROCHLORIDE
  • 1-Piperidinecarboxylicacid,3-amino-,1,1-dimethylethylester,(3R)-(9CI)
  • (R)-3-AMINO-N-BOC-PIPERIDINE
  • (R)-3-AMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
  • (R)-3-AMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER HCL
  • (R)-1-TERT-BUTYLOXYCARBONYL-3-AMINOPIPERIDINE HYDROCHLORIDE
  • (R)-1-BOC-3-PIPERIDINAMINE
  • (R)-1-BOC-3-AMNIOPIPERIDINE
  • (R)-1-BOC-3-AMINOPIPERIDINE
  • (R)-1-BOC-3-AMINOPIPERIDINE HCL
  • (R)-1-N-BOC-3-AMINO PIPERIDINE
  • (R)-N-BOC-3-AMINOPIPERIDINE
  • (R)-TERT-BUTYL 3-AMINOPIPERIDINE-1-CARBOXYLATE
  • TERT-BUTYL (R)-3-AMINO-1-PIPERIDINECARBOXYLATE
  • 2-Methyl-2-propanyl (3S)-3-amino-1-piperidinecarboxylate
  • (3R)-3-Aminopiperidine, N1-BOC protected
  • (3R)-3-Amino-N1-Boc-piperidine
  • (R)-1-Boc-3-aMinopiperidi...
  • (R)-1-Boc-3-AMinopiperidin
  • tert-Butyl (3R)-3-aminopiperidine-1-carboxylate, (3R)-3-Amino-1-(tert-butoxycarbonyl)piperidine
  • (R)-1-Boc-3-AMniopiperidine SynonyMs (R)-3-AMino-1-N-Boc-piperidine
  • (R)-tert-Butyl 3-aMinopiperidine-1-carboxylate, >95%
  • (R)-(-)-3-Amino-1-Boc-piperidine,98%
  • tert-butyl (R)-3-aminopiperidine-1-carboxylate
  • (R)-1-Boc-3-aminopiperidine,99%e.e.
  • 1-T-BUTYLOXYCARBONYL-3-R-AMINOPIPERIDINE HYDROCHLORIDE
  • 1-tert-butyloxycarbonyl-3-r-aminopiperidine
  • 1-PIPERIDINECARBOXYLIC ACID, 3-AMINO-, 1,1-DIMETHYLETHYL ESTER, (3R)-
  • (R)-BOC-PIP(3-NH2) HCL
  • (R)-3-AMINO-1-N-BOC-PIPERIDINE
  • (R)-3-AMINO-1-BOC-PIPERIDINE
  • (R)-3-AMINO-1-BOC-PIPERIDINE HYDROCHLORIDE
  • (R)-1-tert-butoxycarbonyl-3-aminoperidol
  • 3-aminopiperidine-1-carboxyL
  • Linagliptin Impurity 69
  • Linagliptin N-t-BOC Piperidine Impurity
  • Linagliptin Impurity 98
  • (R)-3-aminopiperidine-1-carboxylate
  • ert-butyl(3R)-3-aminopiperidine-1-carboxylate
  • (R)-1-Boc-3-Aminopiperidine USP/EP/BP
  • LigliptinImpurity69
  • (R)-tert-Butyl 3-amino-piperidin-1-carboxylate
  • 188111-79-7
  • 1152113-32-0
  • 1118-90-1
  • C10H21ClN2O2
  • CHIRAL CHEMICALS
  • Piperidines
  • Piperidine Series
  • pharmacetical
  • Piperidine
  • AMINOACID