5-Bromo-2-methylpyridine
Description Referrence- Product Name
- 5-Bromo-2-methylpyridine
- CAS No.
- 3430-13-5
- Chemical Name
- 5-Bromo-2-methylpyridine
- Synonyms
- 5-BROMO-2-PICOLINE;5-BROMOPICOLINE;3-BROMO-6-PICOLINE;2-Methyl-5-bromopyrid;5-Bromo-2-picoline,99%;5-BROMO-2-METHYLPYRIDINE;3-BROMO-6-METHYLPYRIDINE;2-METHYL-5-BROMOPYRIDINE;5-broMo-1-Methylpyridine;5-bormo-2-methylpyridine
- CBNumber
- CB7327298
- Molecular Formula
- C6H6BrN
- Formula Weight
- 172.02
- MOL File
- 3430-13-5.mol
5-Bromo-2-methylpyridine Property
- Melting point:
- 32-36 °C
- Boiling point:
- 74 °C / 17mmHg
- Density
- 1.494±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- form
- Solid
- pka
- 3.59±0.10(Predicted)
- color
- Off-White to Light Yellow
- BRN
- 107324
- InChI
- InChI=1S/C6H6BrN/c1-5-2-3-6(7)4-8-5/h2-4H,1H3
- InChIKey
- OFKWIQJLYCKDNY-UHFFFAOYSA-N
- SMILES
- C1(C)=NC=C(Br)C=C1
- CAS DataBase Reference
- 3430-13-5(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-36-36/37/39
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H301Toxic if swalloed
H311Toxic in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- B2572
- Product name
- 5-Bromo-2-methylpyridine
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $19
- Updated
- 2024/03/01
- Product number
- B2572
- Product name
- 5-Bromo-2-methylpyridine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $58
- Updated
- 2024/03/01
- Product number
- H27085
- Product name
- 5-Bromo-2-methylpyridine, 98%
- Packaging
- 250mg
- Price
- $44.3
- Updated
- 2023/06/20
- Product number
- H27085
- Product name
- 5-Bromo-2-methylpyridine, 98%
- Packaging
- 1g
- Price
- $84.4
- Updated
- 2023/06/20
- Product number
- B685590
- Product name
- 5-Bromo-2-picoline
- Packaging
- 50g
- Price
- $1390
- Updated
- 2021/12/16
5-Bromo-2-methylpyridine Chemical Properties,Usage,Production
Description
It is an important intermediate in the organic synthesis, which has many applications, such as pharmaceutical intermediate, organic synthesis, organic solvent, production of dyes, pesticide, and spice. Specifically, this chemical can act as the raw material to prepare 2:2’-dipyridyl and its derivatives.1 Moreover, this compound may be involved in the synthesis of biaryls through a one-pot tandem borylation/Suzuki-Miyaura cross-coupling reaction catalyzed by a palladacycle.2 In addition, 5-bromo-2-methylpyridine has been demonstrated to function as the substrate in a general palladium-catalyzed coupling of aryl bromides/triflates and thiols.3 Besides, this substance can facilitate the synthesis of 5-arylamino-2-picolines via displacement of bromide by anthranilic acid and decarboxylation.4
Referrence
- Willink, H. D. T.; Wibaut, J. P., The preparation of 2 : 2'-dipyridyl and some of its derivatives. Recueil Des Travaux Chimiques Des Pays-Bas 1935, 54, 275-283.
- Wang, L. H.; Cui, X. L.; Li, J. Y.; Wu, Y. S.; Zhu, Z. W.; Wu, Y. J., Synthesis of Biaryls through a One-Pot Tandem Borylation/Suzuki-Miyaura Cross-Coupling Reaction Catalyzed by a Palladacycle. Eur. J. Org. Chem. 2012, 595-603.
- Itoh, T.; Mase, T., A general palladium-catalyzed coupling of aryl bromides/triflates and thiols. Org. Lett. 2004, 6, 4587-4590.
- Louis H. Peterson; Tolman, R. L., Reinvestigation of the synthesis of 5-arylamino-2-picolines J. Heterocycl. Chem. 1977.
Chemical Properties
Light yellow Cryst
Uses
5-Bromo-2-picoline is a halogenated pyridine derivative used is a building block in the preparation of nitrogen containing heterocyclic compounds.
5-Bromo-2-methylpyridine Preparation Products And Raw materials
Raw materials
Preparation Products
5-Bromo-2-methylpyridine Suppliers
- Tel
- --
- Fax
- --
- info@acros.com
- Country
- Belgium
- ProdList
- 6772
- Advantage
- 81
View Lastest Price from 5-Bromo-2-methylpyridine manufacturers
- Product
- 5-Bromo-2-methylpyridine 3430-13-5
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-02-03
- Product
- 5-Bromo-2-methylpyridine 3430-13-5
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-12
- Product
- 5-Bromo-2-methylpyridine 3430-13-5
- Price
- US $9.00/KG
- Min. Order
- 1KG
- Purity
- 99.9
- Supply Ability
- 1 ton
- Release date
- 2024-08-21