BIOTIN-NHS

Product Name: BIOTIN-NHS
CAS No.: 35013-72-0
Chemical Name: BIOTIN-NHS
Synonyms: NHS-BIOTIN;BIOTIN-OSU;BNHS;2,5-dioxopyrrolidin-1-yl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]iMidazol-4-yl)pentanoate;(2,5-dioxopyrrolidin-1-yl) 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoate;BHSE;BIOTIN SE;BIOTIN-NHS;D-BIOTIN, SE;NHS-D-BIOTIN
CBNumber: CB7371998
Molecular Formula: C14H19N3O5S
Formula Weight: 341.38
MOL File: 35013-72-0.mol

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BIOTIN-NHS Property

Melting point:: 212-214 °C
Density: 1.45±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMF: ≤50 mg/mL Stable for at least one month in dry DMF
form: powder
pka: 13.89±0.40(Predicted)
color: White to off-white
BRN: 4720781
Stability:: Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference: 35013-72-0(CAS DataBase Reference)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 10-23
HS Code: 2934 99 90

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: H1759
Product name: (+)-Biotin N-hydroxysuccinimide ester
Purity: ≥98% (HPLC), powder
Packaging: 5mg
Price: $26.7
Updated: 2024/03/01

Sigma-Aldrich

Product number: H1759
Product name: (+)-Biotin N-hydroxysuccinimide ester
Purity: ≥98% (HPLC), powder
Packaging: 1g
Price: $947
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.51023
Product name: Biotin-OSu
Purity: Novabiochem?
Packaging: 1g
Price: $254
Updated: 2024/03/01

Sigma-Aldrich

Product number: 203112
Product name: Biotin-NHS
Packaging: 250MG
Price: $401
Updated: 2024/03/01

TCI Chemical

Product number: S0491
Product name: N-Succinimidyl D-Biotinate
Purity: >97.0%(HPLC)(N)
Packaging: 100mg
Price: $119
Updated: 2024/03/01

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BIOTIN-NHS Chemical Properties,Usage,Production

Description

N-Hydroxysuccinimide (NHS) activates carboxylic acid groups (on biotin) to facilitate coupling reactions. Biotin-NHS is a compound used to attach biotin to primary amines under alkaline conditions (pH~8-9). For example, lysines on the surface of proteins, including antibodies, are ideal targets for biotinylation with this compound.

Chemical Properties

White Solid

Uses

amine reactive biotinylation reagent

Uses

Biotin-NHS is used in the biotinylation of proteins and peptides. Couples with primary amine in the pH range 6.5-8.5.

Uses

Amino reactive biotin reagent for preparing biotinylated surfaces or polypeptides.

Purification Methods

Recrystallise the ester from refluxing isoPrOH and dry it in a vacuum over P2O5 + KOH. [Jasiewicz et al. Exp Cell Biol 100 213 1976.]

BIOTIN-NHS Preparation Products And Raw materials

Raw materials

Preparation Products

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BIOTIN-NHS Suppliers

Canada 2 China 283 Europe 2 France 1 Germany 7 India 5 Japan 4 Russia 1 South Korea 1 Switzerland 3 United Kingdom 12 United States 63 Global 384

Carbosynth

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Molekula Limited

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Apollo Scientific Ltd

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Manchester Organics

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Cenik Chemicals

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Apollo Scientific Ltd.

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Carbosynth Limited

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Leancare Ltd.

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CARBONE SCIENTIFIC CO.,LTD

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MOLEKULA Ltd.

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Fluorochem Ltd.

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VWR International

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View Lastest Price from BIOTIN-NHS manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: BIOTIN-NHS 35013-72-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2024-08-09

Xian confluore Biological Technology Co., Ltd.

Product: Biotin-NHS ester 35013-72-0
Price: US $0.00/g
Min. Order: 25g
Purity: >95.00%
Supply Ability: 25g
Release date: 2024-03-30

Zhuozhou Wenxi import and Export Co., Ltd

Product: BIOTIN-NHS 35013-72-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

35013-72-0, BIOTIN-NHSRelated Search:

Sulfo-NHS-Biotin BIOTIN-XX-NHS D-BIOTIN P-NITROPHENYL ESTER Succinimidyl 6-(biotinamido)hexanoate N-Hydroxysuccinimide methyl 5-[(1S,2S,5R)-7-oxo-3-thia-6,8-diazabicyclo[3.3.0]oct-2-yl]pent anoate BIOTIN HYDRAZIDE (+)-BIOTIN-EPSILON-AMINOCAPROIC ACID BIOTIN DISULFIDE N-HYDROXY-SUCCINIMIDE ESTER Biotin-NHCH2CH2-SS-Pyr Biotin-SLC-NHS Succinimide BIOTIN-NHS DESTHIOBIOTIN N-HYDROXYSUCCINIMIDYL ESTER 2,5-Dioxopyrrolidin-1-yl octanoate D-DESTHIOBIOTIN D-biotin-d-sulfoxide 7,8-DIAMINOPELARGONIC ACID

(+)-biotin-n-hydroxysuccimide ester

n-hydroxysuccimidobiotin

BIOTIN-OSU: N-HYDROXYSUCCINIMIDOBIOTIN

d-Biotin NHS ester

(2,5-dioxopyrrolidin-1-yl) 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoate

5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID 2,5-DIOXO-PYRROLIDIN-1-YL ESTER

D-(+)BIOTIN N-HYDROXYSUCCINIMIDE ESTER

D-BIOTIN-N-HYDROXYSUCCINIMIDE ESTER

D-BIOTIN, SE

D-BIOTIN, SUCCINIMIDYL ESTER

D-BIOTINYL-OSU

BNHS

BIOTIN-OSU

(+)-BIOTIN N-SUCCINIMIDYL ESTER

BIOTIN-N-HYDROXYSUCCINIMIDE

(+)-BIOTIN-N-HYDROXYSUCCINIMIDE ESTER

BIOTIN-N-HYDROXYSUCCINIMIDE ESTER

BIOTIN-NHS

BIOTIN (LONG ARM) NHS

BIOTIN SE

BIOTIN SUCCINIMIDYL ESTER

BIOTINYL-N-HYDROXY-SUCCINIMIDE

(+)-BIOTINYL-N-SUCCINIMIDYL ESTER

SUCCINIMIDO-(+)-BIOTIN

SUCCINIMIDYL D-BIOTIN

N-HYDROXYSUCCINIMIDOBIOTIN

NHS-BIOTIN

NHS-D-BIOTIN

N-SUCCINIMIDYL D-BIOTINATE

N-SUCCINIMIDO-(+)-BIOTIN

N-Hydroxysuccinimidyl)biotin

(+)-Biotin-NHS Ester

2,5-Dioxopyrrolidin-1-yl 5-((3aS,4S,6aR)

2,5-Dioxopyrrolidin-1-yl 5-((3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentano

Biotin-OSu Novabiochem

Biotin, succinimidyl ester *CAS 35013-72-0*

(+)-Biotin-NHS:BIOTIN-NHS

N-Hydroxysuccinimido Biotin、BNHS

N-Succinimidyl-D-biotin

D-Biotin N-Succinimidyl Ester

N-(D-Biotinyloxy)succinimide

(+)-Biotin N-succinimidyl ester, d-Biotin NHS ester, Biotinyl-N-hydroxy-succinimide, BNHS, N-Hydroxysuccinimidobiotin, N-Succinimidyl D-biotinate, NHS-Biotin

1-[[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]oxy]-2,5-pyrrolidinedione

BHSE

(+)-Biotin N-hydroxysuccinimide ester

Biotin-NHS N-Hydroxysuccimidobiotin

(+)-Biotin N-hydroxysuccinimide ester,(+)-Biotin N-succinimidyl ester, d-Biotin NHS ester, BNHS, Biotinyl-N-hydroxy-succinimide, N-Hydroxysuccinimidobiotin, N-Succinimidyl D-biotinate, NHS-Biotin

BIOTIN-NHS (+)-Biotin N-hydroxysucciniMide ester

2,5-dioxopyrrolidin-1-yl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]iMidazol-4-yl)pentanoate

Hexahydro-2-oxo-

D-Biotin N-Succinimidyl Ester N-(D-Biotinyloxy)succinimide

BNHS, Biotin-NHS

BNHS/NHS-Biotin

(+)-Biotin N-hydroxysuccinimide ester(Biotin-NHS)

2,5-Dioxo-1-pyrrolidinyl 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate

Biotin NHS【2,5-dioxopyrrolidin-1-yl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate】

CAS_35013-72-0

Biotin-N-succinimidyl