ChemicalBook > CAS DataBase List > Basic Orange 14

Basic Orange 14

Product Name
Basic Orange 14
CAS No.
10127-02-3
Chemical Name
Basic Orange 14
Synonyms
ACRIDINE ORANGE;BASIC ORANGE 3RN;Acridine orange, hemi salt;CI 46025;CI 46005;CI NO 46005;EUCHRYSIN GNY;BASIC ORANGE 14;Acridine Orange hemi;ACRIDINE ORANGE ZNCL2
CBNumber
CB7378881
Molecular Formula
C17H20Cl3N3Zn
Formula Weight
438.1
MOL File
10127-02-3.mol
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Basic Orange 14 Property

Melting point:
165 °C
storage temp. 
room temp
solubility 
H2O: soluble1mg/mL, clear, orange to very deep orange
form 
Solid
pka
pKa -3.3(H2O T=room temperature(RT) Iunspeci?ed) (Uncertain);0.2(H2O T=room temperature(RT) Iunspeci?ed) (Uncertain);10.1(H2O T=room temperature(RT) Iunspeci?ed) (Uncertain)
Colour Index 
46005
color 
Red brown
PH
3.9 (10g/l, H2O, 20℃)
Water Solubility 
soluble
Sensitive 
Hygroscopic
BRN 
3734978
Stability:
Stable. Incompatible with strong oxidizing agents. Protect from moisture. Hygroscopic.
CAS DataBase Reference
10127-02-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
68-20/21/22-36/37/38
Safety Statements 
45-36/37-36-26
WGK Germany 
3
RTECS 
AR7600000
HS Code 
32041300
Toxicity
A dye used to stain nucleic acids. It fluoresces at 530 nm when intercalated into double stranded DNA, or at 640 nm when ionically bound to single stranded DNA. It produces mutations, some involving reading frame shifts, other deletions or insertions and is carcinogenic. It is also known to be a dermal phototoxicant.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
158550
Product name
Acridine Orange hemi(zinc chloride) salt
Purity
Dye content 90 %
Packaging
10g
Price
$91.3
Updated
2024/03/01
Sigma-Aldrich
Product number
158550
Product name
Acridine Orange hemi(zinc chloride) salt
Purity
Dye content 90 %
Packaging
25g
Price
$153
Updated
2024/03/01
Sigma-Aldrich
Product number
1.15931
Product name
Acridine orange zinc chloride double salt (C.I.46005)
Purity
for microscopy Certistain?
Packaging
25g
Price
$346
Updated
2022/05/15
TCI Chemical
Product number
A0132
Product name
Basic Orange 14
Packaging
25g
Price
$54
Updated
2023/06/20
Alfa Aesar
Product number
L13159
Product name
Acridine Orange
Packaging
5g
Price
$30.5
Updated
2024/03/01
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Basic Orange 14 Chemical Properties,Usage,Production

Chemical Properties

brown powder

Uses

Fluorescent stain for nucleic acids. An RNA polymerase inhibitorAcridine Orange acts as a lysosomal dye. It is used for cell-cycle studies. It plays an important role as a nucleic acid-selective fluorescent cationic dye, which is useful for cell cycle determination. Further, it serves as an inhibitor of RNA polymerase.

Uses

Acridine Orange, a cell-permeable metachromatic fluorescent cationic dye that intercalates DNA and RNA, is used in fluorescence and epiflouresence microscopy. Acridine Orange dye has been used to analyze mitochondria and lysosomal content by flow cytometry, characterize multidrug resistance, and measure changes in mitochondrial mass during apoptosis in rat thymocytes.

General Description

Acridine orange is a metachromatic fluorescent cationic dye that permeates the cell membrane and intercalates DNA and RNA. It allows for visual detection of nucleic acids on agarose and polyacrylamide gels.

Biochem/physiol Actions

Acridine orange (AO) is a fluorescent dye with two different staining characteristics. In fixed tissues, it acts as a metachromatic dye and differentially stains DNA (green) and RNA (orange). But, in living cells it acts as a pH indicator and produce brilliant orange-red in acidic condition. AO has been used to identify apoptotic cells in drosophila embryos. Acridine Orange staining method has been used to deliver more consistent data in the micronucleus test.

Basic Orange 14 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Basic Orange 14 manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Basic Orange 14 10127-02-3
Price
US $1.00/g
Min. Order
5KG
Purity
80.0%
Supply Ability
10kg/month
Release date
2021-06-08
Career Henan Chemical Co
Product
Basic Orange 14 10127-02-3
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
100kg
Release date
2018-12-24

10127-02-3, Basic Orange 14Related Search:

DIMETHYLAMINOPYRIDINE, POLYMER-BOUND 2-ETHOXY-6,9-DIAMINOACRIDINE Sodium chloride AMINOGUANIDINE HYDROCHLORIDE Amsacrine hydrochloride Zinc chloride Basic Orange 2 6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE Choline chloride Ammonium chloride Topotecan hydrochloride D-Glucosamine hydrochloride Basic Orange Piece 3-Dimethylaminopropylamine ACRIDINE RED 4-AMINOAZOBENZENE HYDROCHLORIDE Quinacridone Acridine

  • Acridine Orange,pure,ca. 55% dye content
  • Acridine Orange hemi
  • Acridine Orange hemi(zinc chloride) salt, 1mg/mL
  • Acridine Orange Euchrysin GNY
  • ACRIDINE ORANGE ZINC CHLORIDE DOUBLE SAL
  • N,N,N',N'-tetramethylacridine-3,6-diamine monohydrochloride, compound with zinc dichloride
  • Acridine orange zinc chloride double salt (C.I.46005) for microscopy Certistain
  • ACRIDINE ORANGE HEMI(ZINC CHLORIDE)
  • ACRIDINE ORANGE C.I. 46005 FOR MICROSCOPY
  • ACRIDINE ORANGE ELECTROPHORESIS GRADE
  • ACRIDINE ORANGE (CI no 46005)
  • 3,6-Bis(dimethylamino)acridineHClzincchloridedoublesalt~C.I.46005
  • ACRIDINE ORANGE (BASIC ORANGE 3RN)
  • Acridine Orange, ca. 55% dye content, pure
  • 3,6-Acridinediamine, N,N,N,N-tetramethyl-, monohydrochloride, compd. with zinc chloride (ZnCl2)
  • ACRIDINE ORANGE: DYE CONTENT 55-60%
  • 3,6-Bis-(dimethylamino)-acridine zinc chloride complex
  • 3,6-Bis(dimethylamino)acridine zinc chloride hydrochloride
  • Acridine orange zinc chloride double salt (C.I.46005)
  • EUCHRYSIN GNY
  • CI 46025
  • CI 46005
  • CI NO 46005
  • BASIC ORANGE 14
  • BASIC ORANGE 3RN
  • ACRIDINE ORANGE
  • ACRIDINE ORANGE BIOLOGICAL STAIN
  • ACRIDINE ORANGE HEMI(ZINC CHLORIDE) SALT
  • ACRIDINE ORANGE, HEMIZINC SALT
  • ACRIDINE ORANGE-ZINC CHLORIDE COMPLEX
  • ACRIDINE ORANGE ZINC CHLORIDE DOUBLE SALT
  • ACRIDINE BRILLIANT ORANGE
  • 3,6-ACRIDINEDIAMINE WITH ZINC CHLORIDE
  • 3,6-BIS(DIMETHYLAMINO)ACRIDINE HEMIZINC CHLORIDE
  • 3,6-BIS[DIMETHYLAMINO]ACRIDINE HEMI[ZINC CHLORIDE] SALT
  • 3,6-BIS(DIMETHYLAMINO)ACRIDINE HYDROCHLORIDE ZINC CHLORIDE DOUBLE SALT
  • 3,6-BIS(DIMETHYLAMINO)ACRIDINIUM CHLORIDE HEMI(ZINC CHLORIDE SALT)
  • Acridine Orange, dye content 55-65%
  • Basic Orange 14, 3,6-Bis(dimethylamino)acridine hydrochloride zinc chloride double salt, 3,6-Bis(dimethylamino)acridinium chloride hemi(zinc chloride salt)
  • 3,6-Acridinediamine, N,N,N',N'-tetramethyl-, monohydrochloride, compound with zinc chloride
  • N,N,N',N'-Tetramethylacridine-3,6-diamine zinc(+2) cation dichloride hydrochloride
  • Acridine Orange, dye content 52%
  • Acridine orange, hemi salt
  • Basic Orange 14 ISO 9001：2015 REACH
  • Acridine Orange (zinc chloride salt)
  • Acridine Orange hemi(zinc chloride) salt, dye content, 90 %
  • Acridine orange for microscopical staining 10GM
  • TIANFU-CHEM Basic Orange 14
  • Acridine Orange hemi(Zinc Chloride) Salt for molecular biology
  • Acridine Orange hemi(Zinc Chloride) Salt for tissue culture
  • N,N,N′,N′-Tetramethylacridine-3,6-diamine monohydrochloride compd. with zinc dichloride
  • ACRIDINE ORANGE ZNCL2
  • Acridine orange hemi(zinc chloride) salt, Fluorescent cationic DNA and RNA dye
  • 10127-02-3
  • C17H19N3HCl12ZnCl2
  • C34H40Cl4N6Zn
  • C17H19N3HCl05ZnCl2
  • C17H19N3ZnCl2HCl