DIETHYL (BOC-AMINO)MALONATE
- Product Name
- DIETHYL (BOC-AMINO)MALONATE
- CAS No.
- 102831-44-7
- Chemical Name
- DIETHYL (BOC-AMINO)MALONATE
- Synonyms
- LABOTEST-BB LT00452467;Diethy (Boc-amino)malonate;DIETHYL (BOC-AMINO)MALONATE;Diethyl 2-(Boc-amino)malonate;Diethyl (Boc-aMino)Malonate,97%;Diethyl (Boc-amino)malonate 97%;(boc-amino)malonic acid diethyl ester;Diethyl (Boc-amino)malonate≥ 99% (GC);DIETHYL (BOC-AMINO)MALONATE USP/EP/BP;Diethyl 2-aminomalonate, N-BOC protected
- CBNumber
- CB7387140
- Molecular Formula
- C12H21NO6
- Formula Weight
- 275.3
- MOL File
- 102831-44-7.mol
DIETHYL (BOC-AMINO)MALONATE Property
- Boiling point:
- 218 °C (lit.)
- Density
- 1.079 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.438(lit.)
- Flash point:
- >230 °F
- storage temp.
- Sealed in dry,2-8°C
- solubility
- Chloroform, Ethyl Acetate, Methanol
- form
- Oil
- pka
- 9.97±0.46(Predicted)
- color
- Colourless
- BRN
- 5055305
- Stability:
- Below-40C
- InChI
- InChI=1S/C12H21NO6/c1-6-17-9(14)8(10(15)18-7-2)13-11(16)19-12(3,4)5/h8H,6-7H2,1-5H3,(H,13,16)
- InChIKey
- ULRLHEXGRUWQLQ-UHFFFAOYSA-N
- SMILES
- C(OCC)(=O)C(NC(OC(C)(C)C)=O)C(OCC)=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 448486
- Product name
- Diethyl (Boc-amino)malonate
- Purity
- 97%
- Packaging
- 25ml
- Price
- $309
- Updated
- 2025/07/31
- Product number
- D443800
- Product name
- Diethyl (Boc-amino)malonate
- Packaging
- 5g
- Price
- $305
- Updated
- 2021/12/16
- Product number
- FD21771
- Product name
- Diethyl (boc-amino)malonate
- Packaging
- 50g
- Price
- $300
- Updated
- 2021/12/16
- Product number
- 6609AH
- Product name
- Diethyl (Boc-amino)malonate
- Packaging
- 5g
- Price
- $157
- Updated
- 2021/12/16
- Product number
- AS44017
- Product name
- Diethyl 2-(tert-Butoxycarbonylamino)malonate
- Purity
- 97%
- Packaging
- 5G
- Price
- $164
- Updated
- 2021/12/16
DIETHYL (BOC-AMINO)MALONATE Chemical Properties,Usage,Production
Chemical Properties
Colourless Oil
Uses
Diethyl (Boc-amino)malonate (cas# 102831-44-7) is a compound useful in organic synthesis.
Synthesis
6829-40-9
24424-99-5
102831-44-7
Diethyl aminomalonate (17.5 g, 0.1 mol) and triethylamine (20 g, 0.2 mol) were dissolved in 250 mL of dichloromethane in a three-necked flask under ice bath conditions. Subsequently, di-tert-butyl dicarbonate (26 g, 0.12 mol) was slowly added. The reaction mixture was gradually brought to room temperature and stirred continuously at this temperature and the progress of the reaction was monitored by thin layer chromatography (TLC). After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was extracted with dichloromethane (200 mL × 3). The organic phases were combined, dried with anhydrous magnesium sulfate, and concentrated to give 27 g of the colorless oily product diethyl 2-Boc-aminomalonate in 98% yield.
References
[1] Journal of Organic Chemistry, 1986, vol. 51, # 15, p. 2910 - 2913
[2] Patent: CN106946724, 2017, A. Location in patent: Paragraph 0027; 0028; 0034; 0040
[3] Bioorganic and Medicinal Chemistry, 2002, vol. 10, # 12, p. 3973 - 3979
[4] Journal of Medicinal Chemistry, 2009, vol. 52, # 9, p. 2909 - 2922
[5] Patent: US2003/65176, 2003, A1
DIETHYL (BOC-AMINO)MALONATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from DIETHYL (BOC-AMINO)MALONATE manufacturers
- Product
- Diethyl (Boc-amino)malonate 102831-44-7
- Price
- US $9.80/KG
- Min. Order
- 1KG
- Purity
- ＞98%HPLC
- Supply Ability
- 20 tons
- Release date
- 2020-02-06