(R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid

ChemicalBook > CAS DataBase List > (R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid

(R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid

Product Name: (R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid
CAS No.: 20445-31-2
Chemical Name: (R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid
Synonyms: Mosher;(R)-3,3,3-Trifluoro-2-Methoxy-2-phenylpropanoic acid;(+)-MTPA;(R)-(+)-MPTA;MOSHERS ACID;AgeSin? MTPA;Mosher’s acid;(+)-MOSHER'S ACID;(R)-(+)-Mosher acid;[Optical Resolving]
CBNumber: CB7461358
Molecular Formula: C10H9F3O3
Formula Weight: 234.17
MOL File: 20445-31-2.mol

Less

(R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid Property

Melting point:: 46-49 °C(lit.)
Boiling point:: 105-107 °C1 mm Hg(lit.)
alpha: D25 +68.5 ± 1.3° (c = 1.49 in CH3OH)
Density: 1.344 g/mL at 25 °C(lit.)
refractive index: n20/D 1.473(lit.)
Flash point:: >230 °F
storage temp.: 2-8°C
solubility: Soluble in methanol (50 mg/ 1 ml).
form: Crystalline Low Melting Solid
pka: 1.47±0.10(Predicted)
Specific Gravity: 1.344
color: White
optical activity: [α]20/D +73±1°, c = 2% in methanol
Sensitive: Hygroscopic
Merck: 14,6280
BRN: 2215440
CAS DataBase Reference: 20445-31-2(CAS DataBase Reference)

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
F: 3-10
Hazard Note: Irritant/Keep Cold
HazardClass: IRRITANT, HYGROSCOPIC, KEEP COLD
HS Code: 29189900

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 155268
Product name: (R)-(+)-α-Methoxy-α-trifluoromethylphenylacetic acid
Purity: 99%
Packaging: 1g
Price: $292
Updated: 2024/03/01

Sigma-Aldrich

Product number: 155268
Product name: (R)-(+)-α-Methoxy-α-trifluoromethylphenylacetic acid
Purity: 99%
Packaging: 5g
Price: $532
Updated: 2024/03/01

TCI Chemical

Product number: M0831
Product name: (R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic Acid [Optical Resolving]
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $197
Updated: 2024/03/01

TCI Chemical

Product number: M0831
Product name: (R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic Acid [Optical Resolving]
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $747
Updated: 2024/03/01

Alfa Aesar

Product number: B22968
Product name: (R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid, 99%
Packaging: 0.1g
Price: $43.65
Updated: 2024/03/01

Less

(R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid Chemical Properties,Usage,Production

Chemical Properties

white crystalline low melting solid

Uses

(R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid is widely used reagent for determination of optical purities of alcohols and amines by 1H or 19F NMR.

Uses

Mosher′s acid chloride is used as a dervatization agent for β-arylethylamines, enantiomeric alcohols, and enantiomeric amines. It is also a reagent used for the determination of enantiomeric purity and absolute configuration of alcohols and amines by NMR.

General Description

Mosher′s acid chloride is generally used as a chiral derivatizing agent. It is easily available in enantiomerically pure form. It can form diastereomers with both alcohols and amines.

Purification Methods

A likely impurity is phenylethylamine from the resolution. Dissolve the acid in Et2O/*benzene (3:1), wash with 0.5N H2SO4, then water, dry over magnesium sulfate, filter, evaporate and distil it. [Dale et al. J Org Chem 34 2543 1969, J Am Chem Soc 75 512 1973.]

(R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Less

(R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid Suppliers

Americas 1 Belgium 3 China 81 Europe 1 France 2 Germany 6 India 5 Japan 5 Switzerland 1 The Netherlands 2 United Kingdom 12 United States 33 Global 152

Shanghai Yichang Chemical Co., Ltd.

Tel: 13472573725
Email: sales@yichangchemical.com
Country: China
ProdList: 348
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44689
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Beijing Ouhe Technology Co., Ltd

Tel: 010-82967028 13552068683
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12438
Advantage: 60

Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

Tel: +86-21-54098501
Fax: +86-21-54096319
Email: sales@sinch.com.cn
Country: China
ProdList: 11598
Advantage: 64

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9809
Advantage: 59

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11707
Advantage: 57

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
Advantage: 55

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9865
Advantage: 52

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-400-6206333 18521732826
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9545
Advantage: 55

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

AllyChem Co., Ltd.

Tel: 0411-62313318 13942603642
Fax: 0411-87549748
Email: info@allychem.com
Country: China
ProdList: 928
Advantage: 65

Suzhou yacoo science co.,Ltd

Tel: 0512-87182056 18013166090
Fax: 0512-87182056
Email: lingling.qi@yacoo.com.cn
Country: China
ProdList: 7295
Advantage: 60

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 16166
Advantage: 55

Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9793
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

JW & Y Pharmlab Co., Ltd.

Tel: 021-64340559 13651849907;
Fax: 021- 64345308
Email: xinyu_shi@jwypharmlab.com.cn
Country: China
ProdList: 12036
Advantage: 58

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 17687
Advantage: 55

Henan CoreyChem Co., Ltd

Tel: 0371-86658258
Fax: 0371-60996044
Email: info@coreychem.com
Country: China
ProdList: 10453
Advantage: 58

Shanghai Xilong Biochemical Technology Co., Ltd.

Tel: 021-52907766-8042
Fax: 021-52906523
Country: China
ProdList: 9941
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27313
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shandong Ono Chemical Co., Ltd.

Tel: 0539-6362799 20）
Fax: 0539-6362799（To 20）
Country: China
ProdList: 10007
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718 +86-13336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29791
Advantage: 60

Aikon International Limited

Tel: 025-58851090 13611564524
Fax: (6)02557626880
Email: lwan@aikonchem.com
Country: China
ProdList: 15951
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 18016230971
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 24969
Advantage: 58

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400-6387771-6038 18902104717
Email: sales@heowns.com
Country: China
ProdList: 21037
Advantage: 60

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52693
Advantage: 58

Beijing OKA biological technology co., LTD

Tel: 010-010-010-62971590 18548936886
Fax: 010-62340519
Email: jack@oka-vip.com
Country: China
ProdList: 6897
Advantage: 58

Beijing Minruida Technology Co., Ltd.

Tel: 010-82387566 18001021521;
Fax: 82387566-801
Email: sales@mreda.com.cn
Country: China
ProdList: 10789
Advantage: 58

Shanghai zhigan biotechnology co., LTD

Tel
Email: zhiqianbio@126.com
Country: China
ProdList: 19778
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34553
Advantage: 58

Hubei Ipure Biology Co., Ltd

Tel: +8613367258412
Fax: 18062427325
Email: ada@ipurechemical.com
Country: China
ProdList: 10319
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: 571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52849
Advantage: 58

HONG KONG IPURE BIOLOGY CO.,LIMITED

Tel: 86 18062405514 18062405514
Email: ada@ipurechemical.com
Country: CHINA
ProdList: 3461
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30241
Advantage: 58

Shanghai jingkang bioengineering co., ltd.

Tel: 021-54721350 13524668266
Fax: 021-5
Email: 2881505714@qq.com
Country: China
ProdList: 7872
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49374
Advantage: 58

Birdo (Shanghai) Medical Technology Co., Ltd.

Tel: 021-021-021-021-58099077-8102-8041-8041-8041 18601625411
Email: sales@birdotech.com
Country: China
ProdList: 9543
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 15850508050
Fax: 025-85563444
Email: info@synzest.com
Country: China
ProdList: 9286
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 13675144456
Fax: 025-85563444
Email: sean.lv@synzest.com
Country: China
ProdList: 10784
Advantage: 58

Lingyuan Bebiansen Biological Technology Co., Ltd

Tel: 18642120371
Email: 2837458851@qq.com
Country: China
ProdList: 7995
Advantage: 58

Suzhou yacoo science co.,Ltd

Tel: 0512-87182056 13451648594
Fax: 0512-87182056
Email: sales@yacoo.com.cn
Country: China
ProdList: 4578
Advantage: 58

Less

View Lastest Price from (R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: (R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid 99% 20445-31-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

20445-31-2, (R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acidRelated Search:

4-Methoxyphenylacetic acid α-Lipoic Acid Ethyl 2-(Chlorosulfonyl)acetate Citric acid 4-(Trifluoromethoxy)aniline (+/-)-ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETIC ACID (R)-(-)-alpha-Methoxyphenylacetic acid (Trifluoromethoxy)benzene Folic acid 3-(Trifluoromethoxy)bromobenzene 4-Methylphenylacetic acid Ascoric Acid 3,3,3-Trifluoropropanal 2-PHENYLPROPIONIC ACID 2-(TRIFLUOROMETHYL)-2-HYDROXYPROPIONIC ACID (+/-)-ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETIC ACID 2-Fluoroethanol Lactic acid

(R)-(+)-MTPA,(R)-(+)-Mosher'sacid

(R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid, 99%(e.e.>99.5%)

(+)--Methoxy--(trifluoromethyl)phenylaceticacid(Moshersacid)

(r)-(+)-à-methoxy-à-(trifluoromethyl)phenylacetic acid

(R)-(+)-1-Methoxy-1-(trifluoromethyl)phenylacetic acid 99% (99%ee)

(R)-(+)-1-Methoxy-1-(trifluoromethyl)phenylacetic acid (99%ee)

(R)-(+)-ɑ-Methoxy-ɑ-(trifluoromethyl)phenylacetic acid, 99%

(R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic Acid [Optical Resolving]

(2R)-(+)-2-Methoxy-2-phenyl-3,3,3-trifluoropropanoic acid 99%

(R)-3,3,3-Trifluoro-2-Methoxy-2-phenylpropanoic acid

(R)-(+)-MTPA, (R)-(+)-Mosher's acid, (R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid

(R)-(+)-Mosher acid

(R)-3,3,3-Trifluoro-2-phenyl-2-methoxypropionic acid

[R,(+)]-3,3,3-Trifluoro-2-methoxy-2-phenylpropionic acid

[R,(+)]-α-Trifluoromethyl-α-methoxyphenylacetic acid

[R,(+)]-β,β,β-Trifluoro-α-methoxyhydratropic acid

(R)-(+)-alpha-Methoxy-alpha-(trifluoroMethyl)phenylacetic Acid&nbsp

[Optical Resolving]

(R)-(+)-α-Methoxy-α-(trifluoroMethyl)phenylacetic Acid [Optical Resolving]

(R)-(+)-2-METHOXY-2-(TRIFLUOROMETHYL)PHENYLACETIC ACID

(R)-(+)-ALPHA-METHOXY-ALPHA-(TRIFLUOROMETHYL)PHENYLACETIC ACID

(R)-(+)-A-METHOXY-A-(TRIFLUOROMETHYL)PHENYLACETIC ACID

(R)-(+)-1-METHOXY-1-(TRIFLUOROMETHYL)PHENYLACETIC ACID

(R)-(+)-MPTA

(R)-(+)-MOSHER'S ACID

(+)-MOSHER'S ACID

MOSHERS ACID

(+)-MTPA

(+)-ALPHA-METHOXY-ALPHA-(TRIFLUOROMETHYL)PHENYLACETIC ACID

(+)-A-METHOXY-A-TRIFLUOROMETHYLPHENYLACETIC ACID

(R)-(+)-α-Methoxy-α-trifluoromethylphenylacetic acid

(R)-(+)-1-Methoxy-1-(trifluoromethyl)phenylaceticacid(ee)

(R)-(+)-α-Methoxy-α-(trifluoroMethyl)phenylacetic acid, ee: 99.5%

(R)-(+)-alpha-Methoxy-alpha-trifluoroMethylphenylacetic acid 99%

Mosher

(2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid

(R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid, 99%(e.e.>99.5%)

(R)-(+)--Methoxy--(trifluoromethyl)phenylacetic acid, 98%, ee: 99.5%

(R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylaceticAcid[OpticalResolving]&gt

Benzeneacetic acid, α-methoxy-α-(trifluoromethyl)-, (αR)-

Benzeneacetic acid, a-methoxy-a-(trifluoromethyl)-, (aR)-

(R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic ac

(R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic Acid [Optical Resolving]

(R)-(+)-α-Methoxy-α-trifluoromethylphenylacetic acid

(+)--methoxy--(trifluoromethyl)phenylacetic acid

(R)-2-Methoxy-2-phenyl-2-(trifluoromethyl)acetic Acid

AgeSin? MTPA

Mosher’s acid

20445-31-2

C6H5COCH3CF3CO2H

C6H5COCH3CF3COOH

C5H5COCH3CF3CO2H

C10H9F3O3

e.e. / Absolute Conefiguration Determination (NMR)

Enantiomer Excess & Absolute Conefiguration Determination

Chiral Resolving Reagents

Chiral Resolution Reagents

Derivatization Reagents