4'-Hydroxy-3'-methylacetophenone
- Product Name
- 4'-Hydroxy-3'-methylacetophenone
- CAS No.
- 876-02-8
- Chemical Name
- 4'-Hydroxy-3'-methylacetophenone
- Synonyms
- 4-HYDROXY-3-METHYLACETOPHENONE;4'-Hydroxy-3'-methyl;4-ACETYL-2-METHYLPHENOL;TrichIoroacetyI chIorine;4'-HYDROXY-3'-METHYLACETOPHENONE;4'-Hydroxy-3'-methylacetophenone;3'-Methyl-4'-Hydroxy Acetophenone;4'-Hydroxy-3'-methylacetophenone>1-(4-HYDROXY-3-METHYLPHENYL)ETHANONE;4’-Hydroxy-3’-Methyl acetophenone99%
- CBNumber
- CB7468317
- Molecular Formula
- C9H10O2
- Formula Weight
- 150.17
- MOL File
- 876-02-8.mol
4'-Hydroxy-3'-methylacetophenone Property
- Melting point:
- 107-109 °C(lit.)
- Boiling point:
- 175°C 1mm
- Density
- 1.0858 (rough estimate)
- refractive index
- 1.5180 (estimate)
- Flash point:
- 175°C/1mm
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 8.52±0.18(Predicted)
- color
- Off-White to Pale Beige
- BRN
- 2041839
- Stability:
- Hygroscopic
- LogP
- 1.395 (est)
- CAS DataBase Reference
- 876-02-8(CAS DataBase Reference)
- NIST Chemistry Reference
- 4-Hydroxy-3-methylacetophenone(876-02-8)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 36/37/39-26-22-37/39
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29143990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- H38004
- Product name
- 4′-Hydroxy-3′-methylacetophenone
- Purity
- 97%
- Packaging
- 5g
- Price
- $30.1
- Updated
- 2023/06/20
- Product number
- H38004
- Product name
- 4′-Hydroxy-3′-methylacetophenone
- Purity
- 97%
- Packaging
- 25g
- Price
- $56.5
- Updated
- 2023/01/07
- Product number
- H0791
- Product name
- 4'-Hydroxy-3'-methylacetophenone
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $32
- Updated
- 2024/03/01
- Product number
- H0791
- Product name
- 4'-Hydroxy-3'-methylacetophenone
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $108
- Updated
- 2024/03/01
- Product number
- A18540
- Product name
- 4'-Hydroxy-3'-methylacetophenone, 98%
- Packaging
- 1g
- Price
- $26.65
- Updated
- 2024/03/01
4'-Hydroxy-3'-methylacetophenone Chemical Properties,Usage,Production
Chemical Properties
white to light beige crystalline powder or
Uses
4''-Hydroxy-3''-methylacetophenone is used in the synthesis of 3-De(hydroxymethyl)-3-methyl Salmeterol (D230650), which is an impurity of β2-Adrenergic agonist Salmeterol (S090100).
Definition
ChEBI: 4-hydroxy-3-methylacetophenone is a monohydroxyacetophenone that is acetophenone carrying methyl and hydroxy groups at positions 3 and 4, respectively. It has a role as a volatile oil component and an insect attractant. It is a monohydroxyacetophenone, a member of phenols and a hydroxytoluene. It is functionally related to an acetophenone.
Preparation
Preparation by dealkylation of 4-hydroxy-5-methyl-2-iso-propylacetophenone with aluminium chloride in chloro-benzene at 50° (53%).
Synthesis Reference(s)
Journal of Medicinal Chemistry, 23, p. 738, 1980 DOI: 10.1021/jm00181a008
4'-Hydroxy-3'-methylacetophenone Preparation Products And Raw materials
Raw materials
Preparation Products
4'-Hydroxy-3'-methylacetophenone Suppliers
- Tel
- --
- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88
- Tel
- --
- Fax
- --
- info@apinchemicals.com
- Country
- United Kingdom
- ProdList
- 6184
- Advantage
- 60
- Tel
- --
- Fax
- --
- kevinbanks@molekula.com
- Country
- United Kingdom
- ProdList
- 6140
- Advantage
- 66
- Tel
- --
- Fax
- --
- sales@carbonesci.com
- Country
- United Kingdom
- ProdList
- 6666
- Advantage
- 30
- Tel
- --
- Fax
- --
- info@manchesterorganics.com
- Country
- United Kingdom
- ProdList
- 6834
- Advantage
- 67
- Tel
- --
- Fax
- --
- sales@gs-chem.com
- Country
- United Kingdom
- ProdList
- 6098
- Advantage
- 47
- Tel
- --
- Fax
- --
- vernam@fluorochem.co.uk
- Country
- United Kingdom
- ProdList
- 6375
- Advantage
- 65
- Tel
- --
- Fax
- --
- enquiries@fluorochem.co.uk
- Country
- United Kingdom
- ProdList
- 6401
- Advantage
- 74
- Tel
- --
- Fax
- --
- info@apinchemicals.com
- Country
- United Kingdom
- ProdList
- 6807
- Advantage
- 42
- Tel
- --
- Fax
- --
- solutions@vwr.com
- Country
- United Kingdom
- ProdList
- 6548
- Advantage
- 82
- Tel
- --
- Fax
- --
- Country
- United Kingdom
- ProdList
- 6309
- Advantage
- 46
View Lastest Price from 4'-Hydroxy-3'-methylacetophenone manufacturers
- Product
- 4'-Hydroxy-3'-methylacetophenone 876-02-8
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.6%
- Supply Ability
- 100 tons
- Release date
- 2022-02-18
- Product
- 4"-Hydroxy-3"-methylacetophenone 876-02-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
- Product
- 4'-Hydroxy-3'-methylacetophenone 876-02-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2019-05-24