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ChemicalBook > CAS DataBase List > 2-ACETYL-6-METHOXYPYRIDINE 97

2-ACETYL-6-METHOXYPYRIDINE 97

Application
Product Name
2-ACETYL-6-METHOXYPYRIDINE 97
CAS No.
21190-93-2
Chemical Name
2-ACETYL-6-METHOXYPYRIDINE 97
Synonyms
2-Acetyl-6-methoxypyridine;2-ACETYL-6-METHOXYPYRIDINE 97;2-Acetyl-6-Methoxypyridine 97%;2-Acetyl-6-methoxypyridine >1-(6-Methoxypyridin-2-yl)ethanone;Ethanone, 1-(6-methoxy-2-pyridinyl)-;1-(6-Methoxypyridin-2-yl)ethan-1-one
CBNumber
CB7500347
Molecular Formula
C8H9NO2
Formula Weight
151.16
MOL File
21190-93-2.mol
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2-ACETYL-6-METHOXYPYRIDINE 97 Property

Melting point:
40-44 °C
Boiling point:
85 °C0.2 mm Hg
Density 
1.093±0.06 g/cm3(Predicted)
Flash point:
202 °F
storage temp. 
Inert atmosphere,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
1.72±0.10(Predicted)
color 
White to Light yellow to Light orange
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26-36/37
WGK Germany 
3
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
662542
Product name
2-Acetyl-6-methoxypyridine
Purity
97%
Packaging
1g
Price
$66.8
Updated
2023/06/20
Sigma-Aldrich
Product number
662542
Product name
2-Acetyl-6-methoxypyridine
Purity
97%
Packaging
5g
Price
$288
Updated
2023/06/20
TCI Chemical
Product number
A2802
Product name
2-Acetyl-6-methoxypyridine
Purity
>97.0%(GC)
Packaging
1g
Price
$146
Updated
2025/07/31
TCI Chemical
Product number
A2802
Product name
2-Acetyl-6-methoxypyridine
Purity
>97.0%(GC)
Packaging
5g
Price
$583
Updated
2024/03/01
TRC
Product number
A189023
Product name
2-Acetyl-6-methoxypyridine
Packaging
500mg
Price
$90
Updated
2021/12/16
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2-ACETYL-6-METHOXYPYRIDINE 97 Chemical Properties,Usage,Production

Application

2-Methoxy-6-acetylpyridine exhibits relatively high chemical reactivity. The methoxy group in its structure can decompose under strong acidic conditions to yield the corresponding pyridinone compounds. The ketone carbonyl unit in its structure can also undergo bromination with brominating agents such as NBS, introducing a bromine atom onto the methyl group. Furthermore, because both the nitrogen atom and the carbonyl oxygen atom in pyridine contain lone pairs of electrons, this substance can coordinate with various metal ions, thus having certain applications in the field of fundamental research in organometallic chemistry.

Synthesis

1628-89-3

75-36-5

21190-93-2

GENERAL METHODS: A mixture of 2-methoxypyridine (1c, 0.216 mg, 2 mmol) and acetyl chloride (2a, 0.157 mg, 2 mmol) was mixed with CTAB/CTAC (0.001 mol) in 1,2-dichloroethane. The resulting reaction mixture was heated in a controlled microwave synthesizer (Biotage Initiator+ SP Wave model, 0.200 W, 2.45 GHz, with an additional 60 W at steady state) for 5 min under reaction conditions of 100 °C and 2 bar pressure. Upon completion of the reaction, the target product 2-acetyl-6-methoxypyridine (3o) was isolated by column chromatography using ethyl acetate-petroleum ether as eluent for purification on silica gel.

References

[1] Tetrahedron Letters, 2013, vol. 54, # 26, p. 3431 - 3436

2-ACETYL-6-METHOXYPYRIDINE 97 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-ACETYL-6-METHOXYPYRIDINE 97 manufacturers

Career Henan Chemical Co
Product
2-ACETYL-6-METHOXYPYRIDINE 97 21190-93-2
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10 tons
Release date
2020-01-10