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Tragacanth gum

Product Name
Tragacanth gum
CAS No.
9000-65-1
Chemical Name
Tragacanth gum
Synonyms
GUM TRAGACANTH;TRAGACANTH;hoggum;C10H30;tragtexr;FEMA 3079;SHIRAZ GUM;GUM SHIRAZ;Tragant gum;goat’sthorn
CBNumber
CB7675665
Molecular Formula
NULL
Formula Weight
840000
MOL File
Mol file
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Tragacanth gum Property

FEMA 
3079 | TRAGACANTH GUM (ASTRAGALUS SPP.)
solubility 
H2O: soluble20mg/mL
form 
powder
color 
Buff coloured powder
Odor
Odorless
Water Solubility 
Slightly soluble in water.
Merck 
14,4581
Stability:
Stable. Incompatible with strong oxidizing agents. High levels of dust in the air create the risk of explosion.
EPA Substance Registry System
Gum tragacanth (9000-65-1)
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Safety

Safety Statements 
22-24/25
WGK Germany 
2
RTECS 
XW7750000
TSCA 
Yes
HS Code 
29400000
Hazardous Substances Data
9000-65-1(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
G1128
Product name
Tragacanth
Packaging
100g
Price
$106
Updated
2024/03/01
Sigma-Aldrich
Product number
G1128
Product name
Tragacanth
Packaging
1kg
Price
$650
Updated
2024/03/01
Alfa Aesar
Product number
A18502
Product name
Tragacanth powder
Packaging
100g
Price
$72.3
Updated
2024/03/01
Alfa Aesar
Product number
A18502
Product name
Tragacanth powder
Packaging
500g
Price
$209
Updated
2024/03/01
Sigma-Aldrich
Product number
G1128
Product name
Tragacanth
Packaging
500g
Price
$351
Updated
2024/03/01
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Tragacanth gum Chemical Properties,Usage,Production

Chemical Properties

light beige powder

Chemical Properties

Tragacanth gum occurs as flattened, lamellated, frequently curved fragments, or as straight or spirally twisted linear pieces from 0.5–2.5mm in thickness; it may also be obtained in a powdered form. White to yellowish in color, tragacanth is a translucent, odorless substance, with an insipid mucilaginous taste.

Chemical Properties

Gum tragacanth is the dried exudate from several species of Astragalus (A. gummifer Labillardiere, or other Asiatic species of Astragalus), a shrub that grows wild in mountainous regions of the Middle East, particularly Iran. The gum is obtained by making incisions in the taproots of the plant; to a lesser extent, the branches also are tapped. The gum exudate is in the form of curled ribbons or flakes, which become horny on drying. Collections are made by hand in May to October and are sorted, graded, packed and shipped. The processor then further grades, cleans, mills and blends the gum, and sells it in the form of ribbons, flakes, granules or powder.

Physical properties

As collected, tragacanth is white to weak yellow, translucent; horny in texture, having a short fracture. It is rendered more easily pulverizable if heated to 50°C. Powdered tragacanth is white to yellowish white. Gum tragacanth swells in cold water to give extremely viscous colloidal solutions, probably the most viscous of all the plant gums.

Uses

In pharmaceutical compounding and dispensing, e.g., to suspend heavy insoluble powders, as an excipient for tablets and to impart consistence to troches; also in making emulsions and emulsifying agents; as stabilizer, thickener, texturizer in food; in adhesives (mucilages, pastes); in textile sizing, textile printing and general printing inks, and in dyeing with insoluble color lakes.

Uses

tragacanth gum is an effective emulsifying agent, binder, film former, and viscosity controller, it is also used as a stabilizing ingredient in lotions. Tragacanth gum is derived from the resin of the Astragalus gummifer shrub.

Uses

Tragacanth is a gum produced from a bush of the genus astragalus. It swells in water to give a highly viscous sol or paste. A 1% solution of the purest gum has a viscosity of approximately 3,400 cps, and about 2% can form a paste. Solutions have a ph of 5–6. It is stable at low ph and is an effective suspending agent because of its stability and acid resistance. It is used in salad dressings, sauces, fruit fillings, and citrus beverages. It is also termed gum tragacanth.

Production Methods

Tragacanth gum is the air-dried gum obtained from Astragalus gummifer Labillardie`re and other species of Astragalus grown principally in Iran, Syria, and Turkey. A low-quality gum is obtained by collecting the natural air-dried exudate from Astragalus bushes. A higher-grade material is obtained by making incisions in the trunk and branches of the bush, which are held open with variously sized wooden pegs. The exudate is left to drain from the incision and dry naturally in the air before being collected. The size and position of the wooden wedges determine the physical form of the exudate, while the drying conditions determine the color of the gum. After collection, the tragacanth gum is sorted by hand into various grades, such as ribbons or flakes.

General Description

Tragacanth is a gum commonly found in the sap of various Middle Eastern legumes. It is commonly used as freezing-embedding medium for tissue preservation.

Pharmaceutical Applications

Tragacanth gum is used as an emulsifying and suspending agent in a variety of pharmaceutical formulations. It is used in creams, gels, and emulsions at various concentrations according to the application of the formulation and the grade of gum used.
Tragacanth gum is also used similarly in cosmetics and food products, and has been used as a diluent in tablet formulations.

Safety Profile

Mildly toxic by ingestion. A mild allergen. A skin and eye irritant. Combustible when exposed to heat or flame. When heated to decomposition it emits acrid smoke and irritating fumes.

Safety

Tragacanth has been used for many years in oral pharmaceutical formulations and food products, and is generally regarded as an essentially nontoxic material. Tragacanth has been shown to be noncarcinogenic. However, hypersensitivity reactions, which are occasionaly severe, have been reported following ingestion of products containing tragacanth. Contact dermatitis has also been reported following the topical use of tragacanth formulations.
The WHO has not specified an acceptable daily intake for tragacanth gum, as the daily intake necessary to achieve a desired effect, and its background levels in food, were not considered to be a hazard to health.
LD50 (hamster, oral): 8.8 g/kg
LD50 (mouse, oral): 10 g/kg
LD50 (rabbit, oral): 7.2 g/kg
LD50 (rat, oral): 16.4 g/kg

storage

Both the flaked and powdered forms of tragacanth are stable. Tragacanth gels are liable to exhibit microbial contamination with enterobacterial species, and stock solutions should therefore contain suitable antimicrobial preservatives. In emulsions, glycerin or propylene glycol are used as preservatives; in gel formulations, tragacanth is usually preserved with either 0.1% w/v benzoic acid or sodium benzoate. A combination of 0.17% w/v methylparaben and 0.03% w/v propylparaben is also an effective preservative for tragacanth gels. Gels may be sterilized by autoclaving. Sterilization by gamma irradiation causes a marked reduction in the viscosity of tragacanth dispersions.
Tragacanth dispersions are most stable at pH 4–8, although stability is satisfactory at higher pH or as low as pH 2. The bulk material should be stored in an airtight container in a cool, dry place.

Incompatibilities

At pH 7, tragacanth has been reported to considerably reduce the efficacy of the antimicrobial preservatives benzalkonium chloride, chlorobutanol, and methylparaben, and to a lesser extent that of phenol and phenylmercuric acetate. However, at pH < 5 tragacanth was reported to have no adverse effects on the preservative efficacy of benzoic acid, chlorobutanol, or methylparaben.
The addition of strong mineral and organic acids can reduce the viscosity of tragacanth dispersions. Viscosity may also be reduced by the addition of alkali or sodium chloride, particularly if the dispersion is heated. Tragacanth is compatible with relatively high salt concentrations and most other natural and synthetic suspending agents such as acacia, carboxymethylcellulose, starch, and sucrose. Ayellow colored, stringy, precipitate is formed with 10% w/v ferric chloride solution.

Regulatory Status

GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (buccal/ sublingual tablets, oral powders, suspensions, syrups, and tablets). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Tragacanth gum Preparation Products And Raw materials

Raw materials

Preparation Products

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Tragacanth gum Suppliers

Shanghai Yuanyuan Biotechnology Co. , Ltd.
Tel
021-58796960 13585883992
Email
herochem021@163.com
Country
China
ProdList
29
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19179
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
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View Lastest Price from Tragacanth gum manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Tragacanth gum 9000-65-1
Price
US $30.00-10.00/KG
Min. Order
50KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-24
airuikechemical co., ltd.
Product
tragacanth gum 9000-65-1
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-04-08
XI'AN TIANGUANGYUAN BIOTECH CO., LTD.
Product
Tragacanth gum 9000-65-1
Price
US $8.00-7.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000
Release date
2023-03-28

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