DIPHTHERIA TOXIN

Product Name: DIPHTHERIA TOXIN
CAS No.: 92092-36-9
Chemical Name: DIPHTHERIA TOXIN
Synonyms: DIPHTHERIA TOXIN;Diphtheria toxin (CRM197);DIPHTHERIA TOXIN, CRM MUTANT;CORYNEBACTERIUM DIPHTHERIAE TOXIN;(GLU-52)-DIPHTHERIA TOXIN FROM*CORYNEBAC;(glu52)-diphtheria toxin from*corynebacterium dip;Diphtheria Toxin from Corynebacterium diphtheriae;Diphtheria toxin[Glu-52], Corynebacterium diphtheriae;DIPHTHERIA TOXIN, UNNICKED, CORYNEBACTERIUM DIPHTHERIAE;[glu52]-diphtheria toxin from corynebacterium diphtheriae
CBNumber: CB7710959
Formula Weight: 0
MOL File: Mol file

More

Less

DIPHTHERIA TOXIN Property

storage temp.: 2-8°C
solubility: Water: soluble
form: lyophilized powder

More

Less

Safety

Hazard Codes: T+
Risk Statements: 28
Safety Statements: 22-24/25-45-36/37-28
RIDADR: 3172
WGK Germany: 3
RTECS: XW5807200
HazardClass: 6.1(a)
PackingGroup: I

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 322326
Product name: Diphtheria Toxin, Unnicked, <i>Corynebacterium diphtheriae</i>
Purity: Diphtheria toxin catalyzes ADP-ribosylation of eukaryotic aminoacyltransferase II (EF2) using NAD as
Packaging: 1 mg
Price: $951
Updated: 2025/07/31

Sigma-Aldrich

Product number: D0564
Product name: Diphtheria Toxin from <I>Corynebacterium diphtheriae</I>
Purity: lyophilized powder, Product is in unnicked form
Packaging: 1 mg
Price: $968
Updated: 2025/07/31

Sigma-Aldrich

Product number: D0564
Product name: Diphtheria Toxin from Corynebacterium diphtheriae
Purity: lyophilized powder, Product is in unnicked form
Packaging: 1MG
Price: $942
Updated: 2024/03/01

Sigma-Aldrich

Product number: 322326
Product name: Diphtheria Toxin, Unnicked, Corynebacterium diphtheriae
Purity: Diphtheria toxin catalyzes ADP-ribosylation of eukaryotic aminoacyltransferase II (EF2) using NAD as substrate. Activation requires nicking with a protease followed by reduction with DTT.
Packaging: 1MG
Price: $925
Updated: 2024/03/01

Sigma-Aldrich

Product number: D2189
Product name: [Glu52]-Diphtheria toxin from Corynebacterium diphtheriae
Purity: lyophilized powder
Packaging: 1mg
Price: $879
Updated: 2023/01/07

More

Less

DIPHTHERIA TOXIN Chemical Properties,Usage,Production

Uses

Diphtheria Toxin, CRM Mutant is an agent that does not have NAD:EF2 ADP-ribosyltransferase activity.

Uses

Diphtheria toxin may be used as a toxin element in the construction of immunotoxin for cell specific cytotoxicity. The translocation domain of bacterial toxins with natural endosome escape mechanism has been used in the development of efficient nonviral vectors for applications in gene therapy.

Biochem/physiol Actions

Inhibits protein synthesis by catalyzing ADP-ribosylation of eukaryotic aminoacyltransferase II.

References

[1] LADOKHIN A S. pH-triggered conformational switching along the membrane insertion pathway of the diphtheria toxin T-domain.[J]. Toxins, 2013, 5 8: 1362-1380. DOI: 10.3390/toxins5081362
[2] MURPHY J R. Mechanism of diphtheria toxin catalytic domain delivery to the eukaryotic cell cytosol and the cellular factors that directly participate in the process.[J]. Toxins, 2011, 3 3: 294-308. DOI: 10.3390/toxins3030294
[3] MAREIKE BÜTEPAGE. Intracellular Mono-ADP-Ribosylation in Signaling and Disease.[J]. Cells, 2015, 4 4: 569-595. DOI: 10.3390/cells4040569

DIPHTHERIA TOXIN Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

DIPHTHERIA TOXIN Suppliers

China 26 Europe 2 Japan 1 Switzerland 1 United Kingdom 1 United States 7 Global 38

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

JiangSu Star Science Co.,Ltd

Tel: 400-605-7200 15335295587
Email: 3941881028@qq.com
Country: China
ProdList: 3760
Advantage: 58

Nantong QuanYi Biotechnology Co., Ltd

Tel: 0513-66337626 18051384581
Email: sales@chemhifuture.com
Country: China
ProdList: 5929
Advantage: 58

PhyCell Medical research Ltd

Tel: 138-18883417 13818883417
Email: 1281600188@qq.com
Country: China
ProdList: 420
Advantage: 58

Shanghai Fine Biotech Co.，Ltd

Tel: 18221172427
Email: sale@fine-biotech.com
Country: China
ProdList: 2760
Advantage: 58

List Biological Laboratories

Tel: 1-610-431-7707 610-431-7707
Email: orders@listlabs.com
Country: China
ProdList: 57
Advantage: 58

Cayman Chemical Company

Tel: 800-364-9897
Email: sales@caymanchem.com
Country: China
ProdList: 6838
Advantage: 58

Merck KGaA

Tel: 21-20338288
Email: ordercn@merckgroup.com
Country: China
ProdList: 6394
Advantage: 58

92092-36-9, DIPHTHERIA TOXINRelated Search:

TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) Tosylmethyl isocyanide 2,4-PENTANEDIONE, SILVER DERIVATIVE Cupric acetylacetonate 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Ferric acetylacetonate SALCOMINE PHENYLSELENOL DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Benzyl isocyanide TERT-BUTYL ISOCYANIDE COBALT(II) ACETYLACETONATE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Aluminum acetylacetonate METHYL ISOCYANOACETATE N-BUTYLISOCYANIDE Tris(2,4-pentanedionato)chroMiuM(III) Ethyl isocyanoacetate

DIPHTHERIA TOXIN

DIPHTHERIA TOXIN, CRM MUTANT

DIPHTHERIA TOXIN, UNNICKED, CORYNEBACTERIUM DIPHTHERIAE

CORYNEBACTERIUM DIPHTHERIAE TOXIN

(glu52)-diphtheria toxin from*corynebacterium dip

(GLU-52)-DIPHTHERIA TOXIN FROM*CORYNEBAC

[glu52]-diphtheria toxin from corynebacterium diphtheriae

Diphtheria toxin[Glu-52], Corynebacterium diphtheriae

Diphtheria Toxin from Corynebacterium diphtheriae

Diphtheria toxin (CRM197)

92092-36-9

Gene Regulation and Expression

RNA-Protein Translation Inhibitors

Cell Biology

Cell Signaling and Neuroscience

BioChemical

Cell Signaling and Neuroscience

Gene Regulation and Expression

BacteriaCell Signaling and Neuroscience

RNA-Protein Translation Inhibitors

Toxins and Venoms