Sodium thiosulfate pentahydrate
- Product Name
- Sodium thiosulfate pentahydrate
- CAS No.
- 10102-17-7
- Chemical Name
- Sodium thiosulfate pentahydrate
- Synonyms
- SODIUM THIOSULPHATE;HYPO;SODIUM THIOSULFATE SOLUTION;Sodium Thiosulfate Hydrate;1kg;4-MPH;SODIUM THIOSULFATE 5 H2O;SodiuM thiosulfate pentahydra;SODIUM THIOSULPHATE PENTAHYDRATE;16g
- CBNumber
- CB8108182
- Molecular Formula
- H10Na2O8S2
- Formula Weight
- 248.18
- MOL File
- 10102-17-7.mol
Sodium thiosulfate pentahydrate Property
- Melting point:
- 48.5 °C
- Boiling point:
- 100 C
- Density
- 1.01 g/mL at 25 °C
- storage temp.
- Store at +5°C to +30°C.
- solubility
- H2O: 1 M at 20 °C, clear, colorless
- form
- Solid
- Specific Gravity
- 1.729
- color
- White tranparent
- Odor
- Odorless
- PH Range
- 6 - 8.5
- PH
- 6.0-7.5 (100g/l, H2O, 20℃)
- Water Solubility
- 680 g/L (20 ºC)
- Merck
- 14,8694
- Stability:
- Stable. Incompatible with strong acids, iodine, mercury.
- InChIKey
- AKHNMLFCWUSKQB-UHFFFAOYSA-L
- LogP
- -0.428 (est)
- CAS DataBase Reference
- 10102-17-7(CAS DataBase Reference)
- EPA Substance Registry System
- Thiosulfuric acid (H2S2O3), disodium salt, pentahydrate (10102-17-7)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 24/25-37/39-36-26
- WGK Germany
- 1
- RTECS
- WE6660000
- F
- 10
- TSCA
- Yes
- HS Code
- 28323000
- Toxicity
- LD50 orally in Rabbit: > 5000 mg/kg
N-Bromosuccinimide Price
- Product number
- 13479
- Product name
- Sodium thiosulfate pentahydrate
- Purity
- puriss., meets analytical specification of Ph. Eur., BP, USP
- Packaging
- 500G
- Price
- $61.3
- Updated
- 2024/03/01
- Product number
- 13479
- Product name
- Sodium thiosulfate pentahydrate
- Purity
- puriss., meets analytical specification of Ph. Eur., BP, USP
- Packaging
- 2.5KG
- Price
- $231
- Updated
- 2024/03/01
- Product number
- 1.09147
- Product name
- Sodium thiosulfate solution
- Purity
- c(Na?S?O? 5 H?O) = 0.1 mol/l (0.1 N) Titripur? Reag. Ph Eur,Reag. USP
- Packaging
- 1L
- Price
- $32.4
- Updated
- 2024/03/01
- Product number
- 1.60318
- Product name
- Sodium thiosulfate solution
- Purity
- 0.01?M Na2S2O3 (0.01 N), Titripur?
- Packaging
- 1L
- Price
- $30.5
- Updated
- 2024/03/01
- Product number
- 1.60311
- Product name
- Sodium thiosulfate solution
- Purity
- 0.05?M Na2S2O3 (0.05 N), Titripur?
- Packaging
- 1L
- Price
- $31.5
- Updated
- 2024/03/01
Sodium thiosulfate pentahydrate Chemical Properties,Usage,Production
Chemical Properties
translucent crystals or white powder
Chemical Properties
Sodium thiosulfate occurs as odorless and colorless crystals, a crystalline powder or granules. It is efflorescent in dry air and deliquescent in moist air.
Uses
Titrimetry.
Uses
Sodium thiosulfate pentahydrate is used as an analytical reagent in laboratories. It is used in photographic processing and in gold extraction. Its alkylated derivatives, S-alkylthiosulfonates, are known as Bunte salts. It is involved in the preparation of thioglycolic acid. Furthermore, it is used to dechlorinate tap water, for removing free bromine from solutions and to check the pH of bleach solutions with liquid indicators. Other uses include tanning of leather; as an active component in hand warmers and chemical heating pads and as an anionic surfactant to aid in the dispersion of pharmaceutical preparations.
Definition
ChEBI: Sodium thiosulfate pentahydrate is a hydrate consisting of sodium thiosulfate with 5 mol eq. of water. It has a role as an antidote to cyanide poisoning, a nephroprotective agent and an antifungal drug. It contains a sodium thiosulfate.
Production Methods
On an industrial scale, sodium thiosulfate is produced chiefly from liquid waste products of sodium sulfide or sulfur dye manufacture. Small-scale synthesis is done by boiling an aqueous solution of sodium sulfite with sulfur.
brand name
Sulfactol (Sterling Winthrop).
Pharmaceutical Applications
Sodium thiosulfate is used as an antioxidant in pharmaceuticals (ophthalmic, intravenous, and oral preparations). It has also been used for its antifungal properties and as a reagent in analytical chemistry.
Safety
Sodium thiosulfate is used in ophthalmic, intravenous, and oral
pharmaceutical preparations. Apart from osmotic disturbances,
sodium thiosulfate is relatively nontoxic. It is moderately toxic by the subcutaneous route and mildly irritating to respiratory tract and
skin. Large oral doses have a cathartic action.
LD50 (IP, mouse) 5.6 g/kg
LD50 (IV, mouse) 2.4 g/kg
storage
Sodium thiosulfate decomposes on heating. The bulk powder should be stored in a cool place, and the container should be kept tightly closed in a dry and well-ventilated place. It should not be stored near acids.
Purification Methods
Crystallise it from EtOH/H2O solutions or from water (0.3mL/g) below 60o by cooling to 0o, and dry it at 35o over P2O5 under vacuum. [Foerster & Mommsen Chem Ber 57 258 1924.] This salt is used as a secondary standard in volumetric analysis [Kilpatrick J Am Chem Soc 45 2132 1923], and is used as “Hypo” in photography [Hargreaves & Dunningham J Soc Chem Ind 42 147T 1923.]
Incompatibilities
Sodium thiosulfate is incompatible with iodine, with acids, and with lead, mercury, and silver salts. It may reduce the activity of some preservatives, including bronopol, phenylmercuric salts, and thimerosal.
Regulatory Status
GRAS listed. Included in the FDA Inactive Ingredients Database (IV solutions; ophthalmic solutions and suspensions; oral capsules, solutions, and tablets). Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Sodium thiosulfate pentahydrate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Sodium thiosulfate pentahydrate manufacturers
- Product
- Sodium thiosulfate pentahydrate 10102-17-7
- Price
- US $6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000KG/Month
- Release date
- 2024-08-14
- Product
- Sodium thiosulfate pentahydrate 10102-17-7
- Price
- US $6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000KG/Month
- Release date
- 2024-08-14
- Product
- Sodium thiosulfate pentahydrate 10102-17-7
- Price
- US $3.60/kg
- Min. Order
- 1kg
- Purity
- ≥99%
- Supply Ability
- 3000tons/month
- Release date
- 2024-07-30