ANTITHROMBIN III
- Product Name
- ANTITHROMBIN III
- CAS No.
- 52014-67-2
- Chemical Name
- ANTITHROMBIN III
- Synonyms
- ATIII;TENSTOP(TM);THROMSTOP(R);ANTITHROMBIN 3;HEPARIN COFACTOR;HUMAN ANTI-THROMBIN;FACTOR XA INHIBITOR;ANTITHROMBIN III PLASMA;ANTITHROMBIN III, HUMAN;ANTITHROMBIN III, HUMAN PLASMA
- CBNumber
- CB8130594
- Formula Weight
- 0
- MOL File
- Mol file
ANTITHROMBIN III Property
- storage temp.
- −20°C
- form
- lyophilized powder
N-Bromosuccinimide Price
- Product number
- A2298-23A
- Product name
- Antithrombin III, Human
- Packaging
- 1mg
- Price
- $460
- Updated
- 2021/12/16
- Product number
- A2298-25A
- Product name
- Antithrombin III, Human
- Packaging
- 1mg
- Price
- $563
- Updated
- 2021/12/16
ANTITHROMBIN III Chemical Properties,Usage,Production
Uses
This recombinant human AT-III product can be used to study the mode of action of the enzyme, as well as its potential inhibitors. It may also be used as a standard, e.g. in antithrombin activity assay, and/or in in vivo studies.
brand name
Kybernin (Hoechst- Roussel); THROMBATE III (Bayer).
Biological Activity
Antithrombin III (AT-III), or Serpin C1 is a serine protease inhibitor glycoprotein, is a member of the Serpin superfamily. Antithrombin III inactivates several components in the coagulation system, IIa,IXa and mainly thrombin and factor Xa. The inhibitory activity of Antithrombin III is potentiated and increased by the polysaccharide heparin. In addition to its abolishment of coagulation, Antithrombin III was also found to suppress proinflammatory mediators, in part by its anticoagulation action. Congenital antithrombin deficiency results in loss of Antithrombin III activity, and leads to thrombosis. Thus, human Antithrombin III enzyme may be prescribed for the treatment and prevention of thromboembolism, as well as for the prevention of perioperative and peripartum thromboembolism.
ANTITHROMBIN III Preparation Products And Raw materials
Raw materials
Preparation Products
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