ACONITASE

Product Name
ACONITASE
CAS No.
9024-25-3
Chemical Name
ACONITASE
Synonyms
ACO1;ACONITASE;EC 4.2.1.3;ACONITATE HYDRATASE;citrate hydro-lyase;Native Porcine Aconitase;ACONITASE, FROM PIG HEART;Ferritin repressor protein;Human ACO1 Protein, His Tag;aconitase from porcine heart
CBNumber
CB8153364
Formula Weight
0
MOL File
Mol file
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ACONITASE Property

storage temp. 
-20°C
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
Toxicity
Aconitase is the enzyme that reversibly interconverts citric acid, cis-aconitic acid, and isocitric acid in the tricarboxylic acid cycle (TCA) (formerly known as the citric acid or Krebs cycle) by dehydration and hydration reactions. Aconitase is the target for fluoroacetate, a potent rodenticide, that condenses with oxaloacetate to yield an aconitase inhibitor (fluorocitric acid), with resultant accumulation of citric acid and thus blockage of the TCA cycle, leading to an inhibition of aerobic energy production.
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A5384
Product name
Aconitase from porcine heart
Packaging
150mg
Price
$443
Updated
2024/03/01
Sigma-Aldrich
Product number
A5384
Product name
Aconitase from porcine heart
Packaging
250mg
Price
$637
Updated
2024/03/01
Usbiological
Product number
353649
Product name
ACO1
Packaging
48Tests
Price
$588
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
ENZ0000753
Product name
ACONITASE
Purity
95.00%
Packaging
5MG
Price
$501.77
Updated
2021/12/16
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ACONITASE Chemical Properties,Usage,Production

Uses

Aconitase may be usefull in diabetes research as well as to study structural conservation between iron-responsive element binding proteins (IRE-BP) and isomerases .

Biochem/physiol Actions

Aconitase catalyses the stereo-specific isomerization of citrate to isocitrate via cis-aconitate in the tricarboxylic acid cycle. Aconitase is inhibited by cyanide, sulfide and copper and mercury at low concentrations. It is competitively inhibited by trans-aconitate. Aconitase contains an internal Fe-S cluster which is responsible for its activity.

ACONITASE Preparation Products And Raw materials

Raw materials

Preparation Products

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ACONITASE Suppliers

SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91

9024-25-3, ACONITASERelated Search:


  • EC 4.2.1.3
  • CITRATE [ISOCITRATE] HYDROLYASE
  • ACONITASE
  • ACONITATE HYDRATASE
  • aconitase from porcine heart
  • ACONITASE, FROM PIG HEART
  • Aconitate hydratase, Citrate (isocitrate) hydrolyase
  • Aconitase, Citrate (isocitrate) hydro-lyase
  • Aconitate hydratase (from Porcine heart), 50% glycerol solution
  • ACO1
  • Anti-IREB1, C-Terminal antibody produced in rabbit
  • citrate hydro-lyase
  • Ferritin repressor protein
  • Anti-IREB1, N-Terminal antibody produced in rabbit
  • Native Porcine Aconitase
  • Human ACO1 Protein, His Tag
  • 9024-25-3
  • BioChemical
  • Metabolomics
  • General Metabolic Enzymes A-H
  • General Metabolic Enzymes
  • enzyme