7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine

Application

Product Name: 7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
CAS No.: 882521-63-3
Chemical Name: 7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
Synonyms: 7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amin;7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine;2-AMino-7-broMo-[1,2,4]triazolo[1,5-a]pyridine;[1,2,4]Triazolo[1,5-a]pyridin-2-amine, 7-bromo-;7-Bromo-1,2,4 Triazolo [1,5-A] Pyridine-2-amine;7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine;7-bromo-[1,2,4triazole combined[1,5-A]pyridine-2-amine;7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine ISO 9001：2015 REACH
CBNumber: CB81560271
Molecular Formula: C6H5BrN4
Formula Weight: 213.03
MOL File: 882521-63-3.mol

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7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine Property

Density: 2.09±0.1 g/cm3(Predicted)
storage temp.: 2-8°C, protect from light
pka: 4.30±0.30(Predicted)
form: solid
Appearance: Off-white to light yellow Solid
InChI: InChI=1S/C6H5BrN4/c7-4-1-2-11-5(3-4)9-6(8)10-11/h1-3H,(H2,8,10)
InChIKey: DAYYXZOMYRSLBX-UHFFFAOYSA-N
SMILES: C12=NC(N)=NN1C=CC(Br)=C2

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Safety

WGK Germany: 3
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SYX00258
Product name: 7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
Purity: Aldrich
Packaging: 1g
Price: $330
Updated: 2025/07/31

TRC

Product number: B614675
Product name: 7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
Packaging: 50mg
Price: $45
Updated: 2021/12/16

TRC

Product number: B614675
Product name: 7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
Packaging: 500mg
Price: $240
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB140382
Product name: 7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine
Packaging: 250mg
Price: $62.5
Updated: 2021/12/16

ChemScene

Product number: CS-W008673
Product name: 7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine
Purity: 97.54%
Packaging: 1g
Price: $93
Updated: 2021/12/16

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7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine Chemical Properties,Usage,Production

Application

7-Bromo-[1,2,4]triazolo[1,5-A]pyridine-2-amine is an organic intermediate that can be prepared by first preparing 1-ethoxycarbonyl-3-(4-bromo-pyridin-2-yl)-thiourea from 4-bromopyridine-2-amine and 4-bromopyridine-2-amine, and then reacting it with hydroxylamine hydrochloride to obtain 7-bromo-[1,2,4]triazolo[1,5-a]pyridine-2-amine.

Synthesis

882521-62-2

882521-63-3

1-Ethoxycarbonyl-3-(4-bromopyridin-2-yl)thiourea (17.5 g, 57.5 mmol) was mixed with hydroxylamine hydrochloride (20.0 g, 288 mmol) and N-ethyl diisopropylamine (30.1 ml, 173 mmol) in ethanol (367 ml). After stirring for a few minutes at room temperature, the reaction mixture was heated to reflux for 24 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. Water (100 ml) was added to the residue and stirred for 10 min to form a suspension. The solid product was collected by filtration, washed with water and dried to give 7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine (10.71 g, 87.4% yield) as a light yellow solid. Melting point: 190-192°C. Mass spectrum (MS): m/z = 213.0, 215.0 ([M+H]+).

References

[1] Patent: WO2012/76430, 2012, A1. Location in patent: Page/Page column 90
[2] Patent: WO2006/38116, 2006, A2. Location in patent: Page/Page column 21
[3] Patent: WO2010/7100, 2010, A1. Location in patent: Page/Page column 40-41
[4] Patent: US2012/142665, 2012, A1. Location in patent: Page/Page column 17
[5] Patent: WO2010/20363, 2010, A1. Location in patent: Page/Page column 129

7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine Suppliers

China 109 India 2 United Kingdom 3 United States 10 Global 124

Accela ChemBio Inc.

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View Lastest Price from 7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine manufacturers

Dideu Industries Group Limited

Product: 7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine 882521-63-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-27

Career Henan Chemical Co

Product: 7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amine 882521-63-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-08

882521-63-3, 7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amineRelated Search:

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2-AMino-7-broMo-[1,2,4]triazolo[1,5-a]pyridine

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7-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-amin

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882521-63-3