Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate
- Product Name
- Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate
- CAS No.
- 158980-21-3
- Chemical Name
- Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate
- Synonyms
- 6-AMINOIMIDAZO[1,2-A]PYR;Ethyl 6-aMinoiMidazo[1,2-a]pyridin-2-carboxylate;ETHYL 6-AMINO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLATE;6-AMINOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER;Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate USP/EP/BP;6-amino-2-imidazo[1,2-a]pyridinecarboxylic acid ethyl ester;Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-amino-, ethyl ester;6-AMINOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER, 95+%;Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-amino-, ethyl ester (9CI);6-amino-Imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester (9CI ACI)
- CBNumber
- CB8189587
- Molecular Formula
- C10H11N3O2
- Formula Weight
- 205.21
- MOL File
- 158980-21-3.mol
Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate Property
- Density
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 3.98±0.50(Predicted)
- Appearance
- Light green to green Solid
N-Bromosuccinimide Price
- Product number
- A612575
- Product name
- 6-Aminoimidazo[1,2-a]pyridine-2-carboxylicacidethylester
- Packaging
- 500mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- 071818
- Product name
- Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $142
- Updated
- 2021/12/16
- Product number
- W3450
- Product name
- Ethyl6-aminoimidazo[1,2-a]pyridine-2-carboxylate
- Packaging
- 10g
- Price
- $771
- Updated
- 2021/12/16
- Product number
- 071818
- Product name
- Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate
- Purity
- 95+%
- Packaging
- 10g
- Price
- $800
- Updated
- 2021/12/16
- Product number
- CHM0960372
- Product name
- 6-AMINOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $958.65
- Updated
- 2021/12/16
Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate Chemical Properties,Usage,Production
Synthesis
38923-08-9
158980-21-3
General procedure for the synthesis of ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate from ethyl 6-nitroimidazo[1,2-A]pyridine-2-carboxylate: 250 mg (1.01 mmol) of ethyl 6-nitroimidazo[1,2-a]pyridine-2-carboxylate was dissolved in 20 ml of ethanol at room temperature, and 30 mg of palladium (10% activated carbon) was added as a catalyst, the hydrogenation reaction was carried out and the reaction lasted for 5 hours at standard atmospheric pressure. After completion of the reaction, the reaction mixture was filtered through diatomaceous earth and the residue was washed with ethanol. The filtrates were combined, concentrated and dried under reduced pressure to give 215 mg of product (quantitative yield). The product was analyzed by LC/MS (Method 5): r = 1.40 mm; MS (ESIpos): m/z = 206 (M + H). 1H-NMR (400 MHz, DMSO-d5) data: δ [ppm] = 8.33 (s, 1H), 7.66 (s, 1H), 7.37 (d, 1H), 6.94 (dd, 1H). 5.11 (s, 2H), 4.26 (q, 2H), 1.29 (t, 3H).
References
[1] Patent: US2016/272637, 2016, A1. Location in patent: Paragraph 0500; 0501; 0502; 0503
[2] Heterocycles, 1994, vol. 38, # 7, p. 1527 - 1532
[3] Molecular Pharmaceutics, 2015, vol. 12, # 6, p. 1813 - 1835
[4] Patent: WO2015/185142, 2015, A1. Location in patent: Page/Page column 20; 21
[5] Patent: WO2008/100423, 2008, A1. Location in patent: Page/Page column 111
Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate Suppliers
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- Country
- United Kingdom
- ProdList
- 6565
- Advantage
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View Lastest Price from Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate manufacturers
- Product
- Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate 158980-21-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95-99%
- Supply Ability
- 1ton
- Release date
- 2020-01-02