ChemicalBook > CAS DataBase List > 1H-INDOL-2-YLMETHANOL

1H-INDOL-2-YLMETHANOL

Product Name
1H-INDOL-2-YLMETHANOL
CAS No.
24621-70-3
Chemical Name
1H-INDOL-2-YLMETHANOL
Synonyms
NSC 165230;1H-Indole-2-methanol;2-HYDROXYMETHYLINDOLE;1H-INDOL-2-YLMETHANOL;indol-2-ylmethan-1-ol;1H-Indole-2-methanol 90%;1H-Indole-2-methanol;2-(Hydroxymethyl)-1H-indole;2-(Hydroxymethyl)-1H-indole 97+%
CBNumber
CB8226451
Molecular Formula
C9H9NO
Formula Weight
147.17
MOL File
24621-70-3.mol
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1H-INDOL-2-YLMETHANOL Property

Melting point:
72-78 °C
Boiling point:
360.6±17.0 °C(Predicted)
Density 
1.272±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
solid
pka
14.86±0.10(Predicted)
Appearance
Light brown to yellow Solid
InChI
InChI=1S/C9H9NO/c11-6-8-5-7-3-1-2-4-9(7)10-8/h1-5,10-11H,6H2
InChIKey
XEEANGGQJOWRTG-UHFFFAOYSA-N
SMILES
N1C2=C(C=CC=C2)C=C1CO
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Safety

Hazard Codes 
Xi
Risk Statements 
41
Safety Statements 
26
WGK Germany 
3
HS Code 
2933998090
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Dam. 1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
687227
Product name
1H-Indole-2-methanol
Purity
90%
Packaging
1g
Price
$95
Updated
2025/07/31
Sigma-Aldrich
Product number
687227
Product name
1H-Indole-2-methanol
Purity
90%
Packaging
5g
Price
$285
Updated
2023/06/20
TRC
Product number
I628088
Product name
(1H-Indol-2-yl)methanol
Packaging
50mg
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
119705
Product name
(1H-Indol-2-yl)methanol
Purity
95+%
Packaging
1g
Price
$90
Updated
2021/12/16
SynQuest Laboratories
Product number
4H56-1-483
Product name
2-(Hydroxymethyl)-1H-indole
Purity
90%
Packaging
1g
Price
$40
Updated
2021/12/16
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1H-INDOL-2-YLMETHANOL Chemical Properties,Usage,Production

Uses

Reactant for the synthesis of:

  • Oxazino[4,3-a]indoles
  • 2-arylsulfonylmethyl-3-piperazinylmethylindole derivatives as 5-HT6 receptor ligands
  • SR13668 designed to mimic the unique anticancer mechanisms of dietary indole-3-carbinol to block Akt signaling
  • Azido- and isothiocyanato-substituted indoles as melatoninergic agents

Synthesis

Put 20kg of 4-oxoindole, 4kg of Pd/C catalyst with 5% Pd content (palladium carbon catalyst) and 60L of diethylene glycol dimethyl ether as solvent into a 100L reactor with stirring device, and then heat up the reactor with steam, turn on the stirring, and carry out catalytic dehydrogenation reaction under the condition of T=150~160??C. After the dehydrogenation reaction, filter it and separate out the Pd/C catalyst, which can be used for recycling. After the dehydrogenation reaction, filtration, separation of the Pd/C catalyst, separated from the Pd/C catalyst can be recycled, the separation of the filtrate pumped to 100L distillation kettle, distillation under reduced pressure, collection of diethylene glycol dimethyl ether fraction (can continue to use), and then collect the product of 2-methylhydroxyindole fraction of 11kg, the mass yield of 55%, content: ?? 99.0%.

1H-INDOL-2-YLMETHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-INDOL-2-YLMETHANOL Suppliers

Baiyin Chengze Chemical Technology Co., Ltd.
Tel
+86 943-8535351 13389336721
Fax
+86-943-8535351
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sales@chengzechem.com
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China
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Energy Chemical
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021-021-58432009 400-005-6266
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021-58436166
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sales8178@energy-chemical.com
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Accela ChemBio Co.,Ltd.
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021-50795510 4000665055
Fax
021-50795055
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sales@accelachem.com
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China
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11034
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ZEROSCHEM.CO.,LTD.
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10-61256048 13810278579
Fax
+86 10 61256049
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sales@zeroschem.com
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China
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Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
Email
info@hanhongsci.com
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China
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42934
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64
Syntechem Co.,Ltd
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Fax
E-Mail Inquiry
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info@syntechem.com
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China
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Acesys Pharmatech
Tel
18860950986
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tangmanman@zenjipharma.com
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China
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Wuxi Zhangkun Biochemical Technology Co., Ltd.
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+86 0510-85629785
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+86 0510-85625359
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China
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Amatek Scientific Co. Ltd.
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0512-56316828 4008675858
Fax
+86-512-56316826
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sales@amateksci.com
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China
ProdList
9872
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Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
40000
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View Lastest Price from 1H-INDOL-2-YLMETHANOL manufacturers

Career Henan Chemical Co
Product
1H-INDOL-2-YLMETHANOL 24621-70-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200KG
Release date
2019-12-25