4-Bromo-3-nitrobenzoic acid

Product Name: 4-Bromo-3-nitrobenzoic acid
CAS No.: 6319-40-0
Chemical Name: 4-Bromo-3-nitrobenzoic acid
Synonyms: RARECHEM AH CK 0042;4-Bromo-3-nitrobenzoicaci;4-BROMO-3-NITROBENZOIC ACID;3-Nitro-4-bromobenzoic acid;2-Bromo-5-carboxynitrobenzene;Benzoic acid, 4-bromo-3-nitro-;4-Bromo-3-nitrobenzoic Acid >4-BROMO-3-NITRO-BENZOIC ACID >97%;4-Bromo-3-nitrobenzoic acid, 95%,;4-Bromo-3-nitrobenzoic acid ISO 9001：2015 REACH
CBNumber: CB8271789
Molecular Formula: C7H4BrNO4
Formula Weight: 246.01
MOL File: 6319-40-0.mol

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4-Bromo-3-nitrobenzoic acid Property

Melting point:: 202-204°C
Boiling point:: 340.9±32.0 °C(Predicted)
Density: 2.0176 (rough estimate)
refractive index: 1.6200 (estimate)
storage temp.: 2-8°C
solubility: soluble in Methanol
form: Solid
pka: 3.35±0.10(Predicted)
color: White to yellow
CAS DataBase Reference: 6319-40-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36/37/39
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29163990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 724734
Product name: 4-Bromo-3-nitrobenzoic acid
Purity: 95%
Packaging: 5g
Price: $24
Updated: 2023/06/20

TCI Chemical

Product number: B3689
Product name: 4-Bromo-3-nitrobenzoic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $67
Updated: 2025/07/31

TCI Chemical

Product number: B3689
Product name: 4-Bromo-3-nitrobenzoic Acid
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $265
Updated: 2025/07/31

TRC

Product number: B697958
Product name: 4-Bromo-3-nitrobenzoic Acid
Packaging: 250mg
Price: $55
Updated: 2021/12/16

TRC

Product number: B697958
Product name: 4-Bromo-3-nitrobenzoic Acid
Packaging: 500mg
Price: $65
Updated: 2021/12/16

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4-Bromo-3-nitrobenzoic acid Chemical Properties,Usage,Production

Chemical Properties

light yellow powder

Synthesis

586-76-5

6319-40-0

The general procedure for the synthesis of 4-bromo-3-nitrobenzoic acid from 4-bromobenzoic acid is as follows: 1. prepare a nitration mixture by slowly adding fuming nitric acid (12.4 mL, 0.3 mol) to concentrated hydrochloric acid followed by sulfuric acid (30.1 mL, 0.6 mol) at 0-5 °C. 2. the cooled nitrification mixture was transferred to a beaker fitted with a mechanical stirrer and a charging funnel. 3. 4-Bromobenzoic acid (40 g, 0.2 mol) was slowly added to the nitrification mixture in batches while maintaining a temperature of 0-5°C. The dosing process lasted for 5 hours. 4. After completion of the addition, the reaction mixture was continued to be stirred at room temperature for 2 hours. 5. The reaction mixture was slowly poured into ice water to precipitate the solid product. 6. The solid product was separated by filtration, washed with water to neutrality and subsequently air dried to constant weight to give the pure 4-bromo-3-nitrobenzoic acid (white solid, 47.2 g, 96% yield). Product characterization data: 1H NMR (300 MHz, CDCl3): δ 7.85 (d, J = 12.0 Hz, 1H), 8.09 (d, J = 12.0 Hz, 1H), 8.48 (s, 1H). 13C NMR (75 MHz, CDCl3): δ 124.2, 132.1, 135.2, 138.0, 139.8, 159.8, 171.0.

References

[1] Beilstein Journal of Organic Chemistry, 2016, vol. 12, p. 2267 - 2273
[2] Patent: US2008/293736, 2008, A1. Location in patent: Page/Page column 32
[3] Patent: WO2017/7634, 2017, A1. Location in patent: Paragraph 0730; 0731; 0732
[4] Patent: WO2005/16882, 2005, A1. Location in patent: Page/Page column 13
[5] Justus Liebigs Annalen der Chemie, 1884, vol. 222, p. 178 Anm. 1

4-Bromo-3-nitrobenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Bromo-3-nitrobenzoic acid Suppliers

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View Lastest Price from 4-Bromo-3-nitrobenzoic acid manufacturers

Henan Fengda Chemical Co., Ltd

Product: 4-Bromo-3-nitrobenzoic acid 6319-40-0
Price: US $100.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-25

Career Henan Chemical Co

Product: 4-Bromo-3-nitrobenzoic acid 6319-40-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg;10kg;100kg
Release date: 2019-08-29

6319-40-0, 4-Bromo-3-nitrobenzoic acidRelated Search:

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RARECHEM AH CK 0042

4-BROMO-3-NITROBENZOIC ACID

4-BROMO-3-NITRO-BENZOIC ACID >97%

3-Nitro-4-bromobenzoic acid

2-Bromo-5-carboxynitrobenzene

4-Bromo-3-nitrobenzoic Acid &gt

Benzoic acid, 4-bromo-3-nitro-

4-Bromo-3-nitrobenzoicaci

4-Bromo-3-nitrobenzoic acid ISO 9001：2015 REACH

4-Bromo-3-nitrobenzoic acid, 95%,

6319-40-0

6319-40-4

intermediate

Benzoic acid

blocks

Bromides

Carboxes

NitroCompounds

Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts