ChemicalBook > CAS DataBase List > Tos-PEG2-t-butyl ester

Tos-PEG2-t-butyl ester

Product Name
Tos-PEG2-t-butyl ester
CAS No.
1309666-78-1
Chemical Name
Tos-PEG2-t-butyl ester
Synonyms
Tos-PEG2-Boc;Tos-PEG1-CH2CH2COOtBu;Tos-PEG2-t-butyl ester;Tos-PEG1-t-butyl ester;Tos-PEG2-tert-butyl ester;tert-Butyl 3-(2-(tosyloxy)ethoxy)propanoate;tert-butyl 3-[2-(4-methylphenyl)sulfonyloxyethoxy]propanoate;Propanoic acid, 3-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]-, 1,1-dimethylethyl ester;Tos-PEG1-CH2CH2COOtBu/Propanoic acid, 3-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]-, 1,1-dimethylethyl ester
CBNumber
CB83167128
Molecular Formula
C16H24O6S
Formula Weight
344.42
MOL File
1309666-78-1.mol
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Tos-PEG2-t-butyl ester Property

Boiling point:
460.6±30.0 °C(Predicted)
Density 
1.164±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
T733953
Product name
Tos-PEG2-t-butylester
Packaging
100mg
Price
$265
Updated
2021/12/16
BroadPharm
Product number
BP-20672
Product name
Tos-PEG2-t-butylester
Purity
95%
Packaging
250mg
Price
$220
Updated
2021/12/16
BroadPharm
Product number
BP-20672
Product name
Tos-PEG2-t-butylester
Purity
95%
Packaging
1g
Price
$550
Updated
2021/12/16
Ambeed
Product number
A743140
Product name
tert-Butyl3-(2-(tosyloxy)ethoxy)propanoate
Purity
95%
Packaging
100mg
Price
$97
Updated
2021/12/16
Ambeed
Product number
A743140
Product name
tert-Butyl3-(2-(tosyloxy)ethoxy)propanoate
Purity
95%
Packaging
250mg
Price
$145
Updated
2021/12/16
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Tos-PEG2-t-butyl ester Chemical Properties,Usage,Production

Description

Tos-PEG2-t-butyl ester is a PEG linker containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

Uses

Tos-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. DOI:10.1038/s12276-018-0065-6

Tos-PEG2-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Tos-PEG2-t-butyl ester Suppliers

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View Lastest Price from Tos-PEG2-t-butyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Tos-PEG2-COOtBu 1309666-78-1
Price
US $0.00/g
Min. Order
1g
Purity
>99.00%
Supply Ability
1g
Release date
2024-03-27

1309666-78-1, Tos-PEG2-t-butyl esterRelated Search:

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  • Tos-PEG2-t-butyl ester
  • Tos-PEG1-CH2CH2COOtBu
  • Tos-PEG2-Boc
  • tert-Butyl 3-(2-(tosyloxy)ethoxy)propanoate
  • Tos-PEG1-CH2CH2COOtBu/Propanoic acid, 3-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]-, 1,1-dimethylethyl ester
  • Propanoic acid, 3-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]-, 1,1-dimethylethyl ester
  • tert-butyl 3-[2-(4-methylphenyl)sulfonyloxyethoxy]propanoate
  • Tos-PEG1-t-butyl ester
  • Tos-PEG2-tert-butyl ester
  • 1309666-78-1