Diethyl bromodifluoromethanephosphonate
- Product Name
- Diethyl bromodifluoromethanephosphonate
- CAS No.
- 65094-22-6
- Chemical Name
- Diethyl bromodifluoromethanephosphonate
- Synonyms
- DIETHYL (BROMODIFLUOROMETHYL)PHOSPHONATE;BROMODIFLUOROMETHYL DIETHYLPHOSPHONATE;BROMODIFLUOROMETHANE DIETHYL PHOSPHATE;Diethyl bromodifluoromethanephosphonat;Diethyl bromodifluoromethanephosphonate;Bromodifluoromethyldiethylphosphonate97%;Bromodifluoromethyl diethylphosphonate 97%;Diethyl P-(bromodifluoromethyl)phosphonate;Diethyl (Bromodifluoromethyl)phosphonate >Diethyl [bromo(difluoro)methyl]phosphonate 97%
- CBNumber
- CB8333674
- Molecular Formula
- C5H10BrF2O3P
- Formula Weight
- 267.01
- MOL File
- 65094-22-6.mol
Diethyl bromodifluoromethanephosphonate Property
- Boiling point:
- 40-41 °C/0.05 mmHg (lit.)
- Density
- 1.503 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.417(lit.)
- Flash point:
- >230 °F
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Chloroform, Ethyl Acetate
- form
- liquid
- Specific Gravity
- 1.503
- color
- colorless
- Water Solubility
- Not miscible or difficult to mix in water.
- BRN
- 1944045
- CAS DataBase Reference
- 65094-22-6(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 21/22-36/38-38-36
- Safety Statements
- 26-36/37/39-60-37-23
- RIDADR
- 3278
- WGK Germany
- 3
- Hazard Note
- Irritant
- TSCA
- No
- HazardClass
- IRRITANT, IRRITANT-HARMFUL
- PackingGroup
- III
- HS Code
- 29319090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 411361
- Product name
- Diethyl (bromodifluoromethyl)phosphonate
- Purity
- 96%
- Packaging
- 5g
- Price
- $102
- Updated
- 2024/03/01
- Product number
- D3071
- Product name
- Diethyl (Bromodifluoromethyl)phosphonate
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $38
- Updated
- 2024/03/01
- Product number
- D3071
- Product name
- Diethyl (Bromodifluoromethyl)phosphonate
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $149
- Updated
- 2024/03/01
- Product number
- L16715
- Product name
- Diethyl (bromodifluoromethyl)phosphonate, 97%
- Packaging
- 1g
- Price
- $24.65
- Updated
- 2024/03/01
- Product number
- L16715
- Product name
- Diethyl (bromodifluoromethyl)phosphonate, 97%
- Packaging
- 5g
- Price
- $73.65
- Updated
- 2024/03/01
Diethyl bromodifluoromethanephosphonate Chemical Properties,Usage,Production
Uses
Efficient difluoroalkylation of aryl boronic acids via palladium catalysis. Novel, moisture-stable bromodifluoromethylated phosphonate, ester, and amide. Efficient coupling with aryl boronic acids via Pd catalysis.
Uses
Diethyl (bromodifluoromethyl)phosphonate is used as a reactant for the preparation of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat3), synthesis of Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory difluoromethylphosphonic acid derivatives via multi step synthesis with Suzuki coupling and resolution as key steps and P-C bond cleavage on basic hydrolysis.
Synthesis Reference(s)
The Journal of Organic Chemistry, 49, p. 3437, 1984 DOI: 10.1021/jo00192a056
Diethyl bromodifluoromethanephosphonate Preparation Products And Raw materials
Raw materials
Preparation Products
Diethyl bromodifluoromethanephosphonate Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
- Tel
- --
- Fax
- --
- Sales@kemikalieimport.dk
- Country
- Europe
- ProdList
- 6685
- Advantage
- 47
View Lastest Price from Diethyl bromodifluoromethanephosphonate manufacturers
- Product
- bromodifluoromethane diethyl phosphate 65094-22-6
- Price
- US $0.10/kg
- Min. Order
- 0.005kg
- Purity
- 99.99%
- Supply Ability
- 20 tons
- Release date
- 2024-04-15
- Product
- Diethyl bromodifluoromethanephosphonate 65094-22-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-09
- Product
- Diethyl bromodifluoromethanephosphonate 65094-22-6
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27