ChemicalBook > CAS DataBase List > 2-Chloroaniline

2-Chloroaniline

Product Name
2-Chloroaniline
CAS No.
95-51-2
Chemical Name
2-Chloroaniline
Synonyms
OCA;O-CHLOROANILINE;2-CHLOROANALINE;Benzenamine, 2-chloro-;2-Chloranilin;o-Chloraniline;2-Chloroanline;2-CHLOROANILINE;o-chloro-anilin;AKOS BBS-00003671
CBNumber
CB8334590
Molecular Formula
C6H6ClN
Formula Weight
127.57
MOL File
95-51-2.mol
More
Less

2-Chloroaniline Property

Melting point:
0-3 °C
Boiling point:
208-210 °C(lit.)
Density 
1.213 g/mL at 25 °C(lit.)
vapor density 
4.41 (vs air)
vapor pressure 
0.5 hPa (20 °C)
refractive index 
n20/D 1.589
Flash point:
98 °C
storage temp. 
Store below +30°C.
solubility 
water: soluble5.13g/L at 20°C
form 
Liquid
pka
2.65(at 25℃)
color 
Clear pale yellow to brown
Odor
Characteristic odour
explosive limit
2.4-14.2%(V)
Water Solubility 
5.13 g/L (20 ºC)
Merck 
14,2118
BRN 
606077
Dielectric constant
13.4
LogP
1.72 at 20℃ and pH6-8
CAS DataBase Reference
95-51-2(CAS DataBase Reference)
NIST Chemistry Reference
o-Chloroaniline(95-51-2)
EPA Substance Registry System
o-Chloroaniline (95-51-2)
More
Less

Safety

Hazard Codes 
T,N,F
Risk Statements 
23/24/25-33-50/53-39/23/24/25-11-52/53
Safety Statements 
28-36/37-45-60-61-28A-16
RIDADR 
UN 2019 6.1/PG 2
WGK Germany 
2
RTECS 
BX0525000
8-10-23
Autoignition Temperature
>500 °C
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
II
HS Code 
29214210
Hazardous Substances Data
95-51-2(Hazardous Substances Data)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H319Causes serious eye irritation

H341Suspected of causing genetic defects

H373May cause damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.02611
Product name
2-Chloroaniline
Purity
for synthesis
Packaging
100mL
Price
$56.7
Updated
2024/03/01
Sigma-Aldrich
Product number
8.02611
Product name
2-Chloroaniline
Purity
for synthesis
Packaging
500mL
Price
$166
Updated
2024/03/01
Sigma-Aldrich
Product number
23300
Product name
2-Chloroaniline
Purity
≥99.5% (GC)
Packaging
100ml
Price
$123
Updated
2024/03/01
TCI Chemical
Product number
C0111
Product name
2-Chloroaniline
Purity
>98.0%(GC)
Packaging
25mL
Price
$30
Updated
2024/03/01
TCI Chemical
Product number
C0111
Product name
2-Chloroaniline
Purity
>98.0%(GC)
Packaging
500mL
Price
$126
Updated
2024/03/01
More
Less

2-Chloroaniline Chemical Properties,Usage,Production

Description

properties:m-isomerColorless to yellow liquid that may turn brown on exposureto air. Molecular weight=127.57; Specific gravity(H2O:1)=1.216; Boiling point (decomposes)=230℃;Melting point=-11℃; Vapor pressure=,0.1 mmHg at20℃; Flash point=118℃(cc); Autoignitiontemperature=.540℃. Slight solubility in water;solubility=0.6%.o-isomerColorless to yellow liquid that may turn brown on exposureto air. Molecular weight=127.57; Specific gravity(H2O:1)=1.21; Boiling point=208.7℃; Meltingpoint=-2℃; Flash point=108℃; Autoignitiontemperature=.500℃; solubility in water=0.5% at 20℃.p-isomer (see also P:0400)The p-isomer is a colorless to pale yellow crystalline solid.Molecular weight=127.6; Specific gravity (H2O:1)=1.4;Boiling point=232℃; Melting point=69.5-72.5℃; Vaporpressure=0.015 mmHg at 20℃; Flash point=120-123℃(oc); Autoignition temperature=685℃. HazardIdentification (based on NFPA 704 M Rating System): p-isomer Health 3, Flammability 1, Reactivity 0. Soluble in hotwater; solubility (cold)=0.4% at 20℃.

Chemical Properties

clear pale yellow to brown liquid with ammonia odor. darkens on exposure to air. almost insoluble in water, soluble in acids and most common organic solvents.

Uses

2-Chloroaniline is the raw material of herbicide green sulfuron, and also an important dye intermediate. It is the color base of ice dyeing dyestuff and can also be used as the diazo component of azo dyestuff to produce acid black, acid blue and organic color precipitation water solid yellow R, permanent red FR, Hansa yellow HR, etc.

Uses

2-Chloroaniline used as petroleum solvents. It is used in biological studies to evaluate the mutagenicity and carcinogenicity of Salmonella typhimurium. Used as a Intermediates for dyestuff, pigment and specialty chemicals. 2-Chloroaniline is widely used in polymer, rubber, pharmaceutical and dye industries.

Preparation

The synthesis method of 2-chloroaniline is to reflux 2-nitrochlorobenzene with iron filings, dilute hydrochloric acid and water for 6~8h, distill to get crude product, and then distill to get finished product.

Synthesis Reference(s)

The Journal of Organic Chemistry, 39, p. 2718, 1974 DOI: 10.1021/jo00932a011
Tetrahedron Letters, 26, p. 3277, 1985 DOI: 10.1016/S0040-4039(00)98171-1

General Description

Clear amber liquid with an amine odor. Occurs in both alpha and beta forms.

Air & Water Reactions

Sensitive to prolonged exposure to air and darkens on exposure to light. Insoluble in water.

Reactivity Profile

2-Chloroaniline is incompatible with acids, acid chlorides, acid anhydrides, chloroformates and strong oxidizing agents.

Hazard

Toxic by ingestion.

Fire Hazard

2-Chloroaniline is combustible.

Safety Profile

Poison by skin contact, ingestion, and subcutaneous routes. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl and NOx. See also ANILINE DYES.

Potential Exposure

RTECS Compound Description (mand o-isomers): Tumorigen, Mutagen (p-isomer):Tumorigen, Mutagen, Primary Irritant. Chloroanilines areused to make dyes, other chemicals, insecticides, and manyother industrial products.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.Medical observation is recommended.
Note to physician: Treat for methemoglobinemia.Spectrophotometry may be required for precise determination of levels of methemoglobinemia in urine.

storage

Color Code—Blue: Health Hazard/Poison (p-isomer): Store in a secure poison location. Prior to workingwith chloroaniline you should be trained on its proper handling and storage. Store in tightly closed containers in acool, well-ventilated area away from oxidizers (such asperchlorates, peroxides, permanganates, chlorates, andnitrates), since violent reactions occur. A regulated, markedarea should be established where this chemical is handled,used, or stored in compliance with OSHA Standard1910.1045.

Shipping

Chloroanilines are required by DOT to carry a“POISONOUS/TOXIC MATERIALS” label. They fall inHazard Class 6.1 and Packing Group II.

Purification Methods

Free it from small amounts of the p-isomer by dissolving in one equivalent of H2SO4 and steam distilling. The p-isomer remains behind as the sulfate. [Sidgwick & Rubie J Chem Soc 1013 1921.] An alternative method is to dissolve it in warm 10% HCl (11mL/g of amine) and on cooling, o-chloroaniline hydrochloride separates out. The latter can be recrystallised until the acetyl derivative has a constant melting point (m 90o). (In this way, yields are better than via the recrystallisation of the picrate from EtOH or of the acetyl derivative from pet ether.) [King & Orton J Chem Soc 1377 1911]. [Beilstein 12 III 1281, 12 IV 1115.]

Incompatibilities

Contact with strong oxidizers may causefire and explosions. The aqueous solution of the m-isomeris a weak base. Incompatible with strong acids, organicanhydrides, isocyanates, aldehydes.

More
Less

2-Chloroaniline Suppliers

SHANGHAI BANGCHENG CHEMICAL Co.,Ltd.
Tel
021-69106960 13701823733
Fax
021-69106780
Email
13701823733@163.com
Country
China
ProdList
4776
Advantage
60
Qingdao Dexin Chemical Co., Ltd
Tel
15564477061
Email
1397986535@qq.com
Country
China
ProdList
293
Advantage
58
Changzhou Yunlong Chemical New Materials Co., Ltd
Tel
18967392038
Email
hwh4319359@163.com
Country
China
ProdList
18
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7508
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2883
Advantage
65
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12426
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9555
Advantage
66
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
XiaoGan ShenYuan ChemPharm co,ltd
Tel
0712-0712-2580635 15527768850
Email
1791901229@qq.com
Country
China
ProdList
8850
Advantage
52
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18736
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7815
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9664
Advantage
60
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9725
Advantage
55
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9872
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6139
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
24835
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9552
Advantage
55
Cantotech Chemicals, Ltd.
Tel
86-0755-86635001
Fax
86-0755-22642228
Email
cantotech@126.com
Country
China
ProdList
4576
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9906
Advantage
55
Anichem Inc.
Tel
0512-69369885
Fax
0512-69369880
Email
sales@anichem.com.cn
Country
China
ProdList
497
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8033
Advantage
55
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3933
Advantage
58
Shanghai BeiZhuo Biotech Co., Ltd.
Tel
021-61119791,13386096464
Fax
021-50190009
Email
bzswkf@foxmail.com
Country
China
ProdList
3924
Advantage
50
Hubei XinyuanShun Chemical Co., Ltd.
Tel
13971561712, 13995564702, 027-50664929
Fax
027-50664927
Email
hbeixys2001@163.com
Country
China
ProdList
3123
Advantage
55
Huainan Kedi Chemical Factory
Tel
0554-2106669
Fax
0554-2666215
Email
sales1@kedichem.com
Country
China
ProdList
4928
Advantage
55
RiZhao LiDeShi Chemical Co., Ltd.
Tel
010-51268198
Fax
010-63833209
Email
leadershipchem@126.com
Country
China
ProdList
2549
Advantage
58
Mei Lan Industrial (Shanghai) Co., Ltd.
Tel
021-58958189
Fax
021-58957967
Email
wouchina@126.com
Country
China
ProdList
2671
Advantage
55
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9353
Advantage
58
Shanghai ideal Industrial Co., Ltd.
Tel
021-58957966 18930537195
Fax
021-60899437
Email
wouchina@126.com
Country
China
ProdList
2873
Advantage
58
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ:800101999
Email
cdhxsj@163.com
Country
China
ProdList
13358
Advantage
58
GuangTuo Chemical (Shanghai) Co., Ltd.
Tel
021-60899189-8001 18918189673
Fax
021-60899304
Email
gtchem@126.com
Country
China
ProdList
2661
Advantage
58
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5223
Advantage
58
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4951
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10287
Advantage
55
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15873
Advantage
55
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9912
Advantage
50
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6490
Advantage
50
More
Less

View Lastest Price from 2-Chloroaniline manufacturers

Hebei Mojin Biotechnology Co., Ltd
Product
2-Chloroaniline 95-51-2
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-06-29
Hebei Guanlang Biotechnology Co., Ltd.
Product
2-Chloroaniline 95-51-2
Price
US $1.00/PCS
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2021-06-08
Shaanxi Dideu Medichem Co. Ltd
Product
2-Chloroaniline 95-51-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2019-12-30

95-51-2, 2-ChloroanilineRelated Search:


  • Benzenamine,2-chloro-
  • Benzeneamine,2-chloro-
  • o-Aminochlorobenzene
  • o-Aminochloro-benzene
  • o-Chloraniline
  • o-Chloroaminobenzene
  • o-chloro-anilin
  • AKOS BBS-00003671
  • 1-AMINO-2-CHLOROBENZENE
  • 2-CHLOROANILINE
  • 2-CHLOROBENZENAMINE
  • 2-CHLOROPHENYLAMINE
  • 1,2-aminochlorobenzene
  • 2-chloro-benzenamin
  • Aniline, o-chloro-
  • Azoic diazo component 44, base
  • Benzenamine, 2-chloro-
  • FAST YELLOW GC BASE
  • 2-CHLOROANILINE, 1000MG, NEAT
  • 2-Chloroaniline, CP,97%
  • ORTHO-CHLOROANILINE
  • O-CHLOROANILINE
  • OCA
  • 2-Chloroaniline >=99.5% (GC)
  • 2-CHLOROANILINE PESTANAL
  • 2-CHLOROANILINE, 1X1ML, MEOH, 2000UG/ML
  • 2-Chloroaniline,>99%
  • 2-Chloroaniline, 98+%
  • 2-chloroaniline solution
  • 2-Chloroaniline 98%
  • 2-Aminochlorobenzene
  • ORTHO-CHLORANILINE
  • 2-CHLOROBENZAMINE
  • 2-CHLOROANALINE
  • 2-Chloranilin
  • 2-Chloroaminobenzene
  • C.I.Azoic Diazo Component 44【base】
  • 2-Chloroanline
  • 2-Chloroaniline 5g [95-51-2]
  • 2-Chloroaniline 10g [95-51-2]
  • 2-Chloroaniline, 98+% 250ML
  • o-Chloroaniline fast yellow gc base
  • 2-ChloroanilineSolution,1000mg/L,1ml
  • 2-Chloroaniline &gt
  • 2-ChloroanilineSolution,2000mg/L,1ml
  • 2-ChloroanilineSolution,100mg/L,1ml
  • 2-Chloroaniline Solution in Methanol, 1000μg/mL
  • 2-Chloroaniline ISO 9001:2015 REACH
  • TIANFU-CHEM CAS:95-51-2 2-Chloroaniline
  • o-Chloroaniline extrapure, 99%
  • Ortho Chloro Aniline (OCA)
  • Trazodone impurity QZT-SM-3-Z5
  • Trazodone Impurity 23 (2-Chloroaniline)
  • 95-51-2
  • 95512
  • Organic Building Blocks
  • Nitrogen Compounds
  • C2 to C6