ChemicalBook > CAS DataBase List > Chorionic Gonadotropin

Chorionic Gonadotropin

Product Name
Chorionic Gonadotropin
CAS No.
9002-61-3
Chemical Name
Chorionic Gonadotropin
Synonyms
HCG;HUMAN CHORIONIC GONADOTROPIN;LHA;HUMAN CHORIONIC GONADOTROPHIN;apl;pregnyl;HCG 5000IU;choragon;CHORIONIC GONADOTROPIN HUMAN;HGG
CBNumber
CB8353322
Molecular Formula
C17H28
Formula Weight
232.40422
MOL File
9002-61-3.mol
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Chorionic Gonadotropin Property

storage temp. 
2-8°C
solubility 
H2O: soluble1ML/vial
form 
lyophilized powder
color 
White to off-white
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Safety

Hazard Codes 
B,Xn
Risk Statements 
63-62
Safety Statements 
22-36-36/37
WGK Germany 
3
RTECS 
MD6953000
HS Code 
2937190000
Hazardous Substances Data
9002-61-3(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P281Use personal protective equipment as required.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CG5
Product name
Chorionic gonadotropin human
Purity
lyophilized powder, vial of ~5,000?IU
Packaging
1vial
Price
$169
Updated
2024/03/01
Sigma-Aldrich
Product number
CG5
Product name
Chorionic gonadotropin human
Purity
lyophilized powder, vial of ~5,000?IU
Packaging
10vials
Price
$1060
Updated
2024/03/01
Sigma-Aldrich
Product number
CG10
Product name
Chorionic gonadotropin human
Purity
lyophilized powder, vial of ~10,000?IU
Packaging
1vial
Price
$223
Updated
2024/03/01
Sigma-Aldrich
Product number
CG10
Product name
Chorionic gonadotropin human
Purity
lyophilized powder, vial of ~10,000?IU
Packaging
10vials
Price
$1420
Updated
2024/03/01
Sigma-Aldrich
Product number
C1063
Product name
Chorionic gonadotropin human
Purity
lyophilized powder, vial of ~2,500?IU
Packaging
1VIAL
Price
$97.2
Updated
2024/03/01
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Chorionic Gonadotropin Chemical Properties,Usage,Production

Chemical Properties

White or yellowish-white, amorphous powder.

Uses

Gonad-stimulating principle.

Uses

Chorionic gonadotropin human has been used:

  • to induce oocyte maturation in cultured follicles
  • along with pregnant mare serum gonadotropin (PMSG) to induce superovulation in mice
  • as medium component for fetal testes culture to aid steroidogenic responsiveness

Production Methods

CG is produced in the chorion.

Application

Human chorionic gonadotropin (hCG) is a chemical produced by the trophoblast tissue, which is usually present in the early embryo and will eventually become part of the placenta. Measuring hCG levels helps to identify normal, pathological and miscarried pregnancies. Measuring hCG is also beneficial for many cancers including choriocarcinoma and extrauterine malignancies.

brand name

A.P.L. (Ferring Pharmaceuticals); Follutein (Bristol-Myers Squibb); Pregnyl (Organon).

General Description

Glycoprotein hormone consisting of a 92-amino acid α-chain which is identical to that of LH, FSH, and TSH; and a distinct 149-amino acid β-chain. Produced by chorionic tissue and responsible for maintaining the corpus luteum during early pregnancy. Also produced by trophoblast cell neoplasms, which are marked by elevated free hCG β-chains and hyperglycosylated hCG.

Biochem/physiol Actions

Elevated levels of hCG is observed in trophoblastic cancer. hCG levels are indicators of pregnancy and β subunit is majorly present in urine samples. hCG isoform detection is useful in the diagnosis and management of trophoblastic related diseases including carcinomas.

Clinical Use

Choriogonadotropin alfa is obtained by rDNA technology and is biologically and chemically identical to hCG of natural origin. It is used, like hCG of natural origin, for inducing ovulation in women with anovulatory infertility. Following proper pretreatment with a GnRH antagonist or superagonist to desensitize the pituitary, women participating in ART are treated with a folliclestimulating agent (e.g., menotropins) to effect the final maturation of the follicles within the ovaries. Ultrasonograms are used to determine proper follicle maturation before the administration of choriogonadotropin alfa to induce ovulation. A distinct advantage of this product is that it can be self-administered by the patient via SC injection.

Veterinary Drugs and Treatments

The veterinary product’s labeled indication is for “parenteral use in cows for the treatment of nymphomania (frequent or constant heat) due to cystic ovaries.” It has been used for other purposes in several species; refer to the Dosage section for more information.

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View Lastest Price from Chorionic Gonadotropin manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
HCG 9002-61-3
Price
US $120.00-100.00/box
Min. Order
1box
Purity
99.99%
Supply Ability
500 box
Release date
2024-03-14
Strong peptide cross-border e-commerce Co. LTD
Product
APL (hormone) 9002-61-3
Price
US $5.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
200t
Release date
2024-05-15
Strong peptide cross-border e-commerce Co. LTD
Product
Chorionic Gonadotropin 9002-61-3
Price
US $5.00/kg
Min. Order
1kg
Purity
99+
Supply Ability
200t
Release date
2024-05-16

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