ChemicalBook > CAS DataBase List > Chorionic Gonadotropin

Chorionic Gonadotropin

Product Name
Chorionic Gonadotropin
CAS No.
9002-61-3
Chemical Name
Chorionic Gonadotropin
Synonyms
HCG;HUMAN CHORIONIC GONADOTROPIN;LHA;HUMAN CHORIONIC GONADOTROPHIN;apl;pregnyl;HCG 5000IU;choragon;CHORIONIC GONADOTROPIN HUMAN;HGG
CBNumber
CB8353322
Molecular Formula
C17H28
Formula Weight
232.40422
MOL File
9002-61-3.mol
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Chorionic Gonadotropin Property

storage temp. 
2-8°C
solubility 
H2O: soluble1ML/vial
form 
lyophilized powder
color 
White to off-white
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Safety

Hazard Codes 
B,Xn
Risk Statements 
63-62
Safety Statements 
22-36-36/37
WGK Germany 
3
RTECS 
MD6953000
HS Code 
2937190000
Hazardous Substances Data
9002-61-3(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P281Use personal protective equipment as required.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CG5
Product name
Chorionic gonadotropin human
Purity
lyophilized powder, vial of ~5,000?IU
Packaging
1vial
Price
$169
Updated
2024/03/01
Sigma-Aldrich
Product number
CG5
Product name
Chorionic gonadotropin human
Purity
lyophilized powder, vial of ~5,000?IU
Packaging
10vials
Price
$1060
Updated
2024/03/01
Sigma-Aldrich
Product number
CG10
Product name
Chorionic gonadotropin human
Purity
lyophilized powder, vial of ~10,000?IU
Packaging
1vial
Price
$223
Updated
2024/03/01
Sigma-Aldrich
Product number
CG10
Product name
Chorionic gonadotropin human
Purity
lyophilized powder, vial of ~10,000?IU
Packaging
10vials
Price
$1420
Updated
2024/03/01
Sigma-Aldrich
Product number
C1063
Product name
Chorionic gonadotropin human
Purity
lyophilized powder, vial of ~2,500?IU
Packaging
1VIAL
Price
$97.2
Updated
2024/03/01
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Chorionic Gonadotropin Chemical Properties,Usage,Production

Chemical Properties

White or yellowish-white, amorphous powder.

Uses

Gonad-stimulating principle.

Uses

Chorionic gonadotropin human has been used:

  • to induce oocyte maturation in cultured follicles
  • along with pregnant mare serum gonadotropin (PMSG) to induce superovulation in mice
  • as medium component for fetal testes culture to aid steroidogenic responsiveness

Production Methods

CG is produced in the chorion.

Application

Human chorionic gonadotropin (hCG) is a chemical produced by the trophoblast tissue, which is usually present in the early embryo and will eventually become part of the placenta. Measuring hCG levels helps to identify normal, pathological and miscarried pregnancies. Measuring hCG is also beneficial for many cancers including choriocarcinoma and extrauterine malignancies.

brand name

A.P.L. (Ferring Pharmaceuticals); Follutein (Bristol-Myers Squibb); Pregnyl (Organon).

General Description

Glycoprotein hormone consisting of a 92-amino acid α-chain which is identical to that of LH, FSH, and TSH; and a distinct 149-amino acid β-chain. Produced by chorionic tissue and responsible for maintaining the corpus luteum during early pregnancy. Also produced by trophoblast cell neoplasms, which are marked by elevated free hCG β-chains and hyperglycosylated hCG.

Biochem/physiol Actions

Elevated levels of hCG is observed in trophoblastic cancer. hCG levels are indicators of pregnancy and β subunit is majorly present in urine samples. hCG isoform detection is useful in the diagnosis and management of trophoblastic related diseases including carcinomas.

Clinical Use

Choriogonadotropin alfa is obtained by rDNA technology and is biologically and chemically identical to hCG of natural origin. It is used, like hCG of natural origin, for inducing ovulation in women with anovulatory infertility. Following proper pretreatment with a GnRH antagonist or superagonist to desensitize the pituitary, women participating in ART are treated with a folliclestimulating agent (e.g., menotropins) to effect the final maturation of the follicles within the ovaries. Ultrasonograms are used to determine proper follicle maturation before the administration of choriogonadotropin alfa to induce ovulation. A distinct advantage of this product is that it can be self-administered by the patient via SC injection.

Veterinary Drugs and Treatments

The veterinary product’s labeled indication is for “parenteral use in cows for the treatment of nymphomania (frequent or constant heat) due to cystic ovaries.” It has been used for other purposes in several species; refer to the Dosage section for more information.

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Chorionic Gonadotropin Suppliers

Qingdao Kangyuan Pharmaceutical Co., Ltd.
Tel
Email
office@kangyuan.com.cn
Country
China
ProdList
3
Advantage
58
Hebei ruqi technology co., ltd
Tel
176-03256889 17603256889
Email
1123722730@qq.com
Country
China
ProdList
3376
Advantage
58
Lanzhou Zhichun Chemical Co. LTD
Tel
18893111699 18893111699
Email
huoyi@pure-chem.net
Country
China
ProdList
107
Advantage
58
Hubei Lingyan Biotechnology Co., Ltd
Tel
027-59304846 13297025796
Email
2331003879@qq.com
Country
China
ProdList
60
Advantage
58
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ:800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
Advantage
55
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9484
Advantage
50
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View Lastest Price from Chorionic Gonadotropin manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
HCG 9002-61-3
Price
US $120.00-100.00/box
Min. Order
1box
Purity
99.99%
Supply Ability
500 box
Release date
2024-03-14
Strong peptide cross-border e-commerce Co. LTD
Product
APL (hormone) 9002-61-3
Price
US $5.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
200t
Release date
2024-05-15
Strong peptide cross-border e-commerce Co. LTD
Product
Chorionic Gonadotropin 9002-61-3
Price
US $5.00/kg
Min. Order
1kg
Purity
99+
Supply Ability
200t
Release date
2024-05-16

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