L-2-Aminobutyric acid hydrochloride
- Product Name
- L-2-Aminobutyric acid hydrochloride
- CAS No.
- 5959-29-5
- Chemical Name
- L-2-Aminobutyric acid hydrochloride
- Synonyms
- AA3;DL-.alph;H-ABU-OH HCL;H-L-2ABU-OH HCL;HoMoalanine HCl;H-2-Abu-OH x HCl;2-ammoniobutyrate;2-ammoniobutanoate;2-azaniumylbutanoate;HOMOALANINE HYDROCHLORIDE
- CBNumber
- CB8364049
- Molecular Formula
- C4H10ClNO2
- Formula Weight
- 139.58
- MOL File
- 5959-29-5.mol
L-2-Aminobutyric acid hydrochloride Property
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- White to Off-White
- optical activity
- Consistent with structure
- CAS DataBase Reference
- 5959-29-5(CAS DataBase Reference)
Safety
- HazardClass
- IRRITANT
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A602935
- Product name
- (S)-2-AminobutanoicAcidHydrochloride
- Packaging
- 5g
- Price
- $125
- Updated
- 2021/12/16
- Product number
- HAA1247
- Product name
- H-L-2Abu-OH*HCl
- Packaging
- 5G
- Price
- $135
- Updated
- 2021/12/16
- Product number
- AS49319
- Product name
- (S)-2-Aminobutanoic acid hydrochloride
- Purity
- 95% ee
- Packaging
- 25g
- Price
- $247
- Updated
- 2021/12/16
- Product number
- HAA1247
- Product name
- H-L-2Abu-OH*HCl
- Packaging
- 25g
- Price
- $506.25
- Updated
- 2021/12/16
- Product number
- J56852
- Product name
- (S)-2-Aminobutanoicacidhydrochloride
- Packaging
- 1g
- Price
- $20
- Updated
- 2021/12/16
L-2-Aminobutyric acid hydrochloride Chemical Properties,Usage,Production
Uses
(S)-2-Aminobutanoic Acid Hydrochloride is an intermediate in the synthesis of Levetiracetam (L331500), which is used as an anticonvulsant.
Synthesis
34047-84-2
5959-29-5
The general procedure for the synthesis of L-2-aminobutyric acid hydrochloride from the compound (CAS: 34047-84-2) was as follows: in step 3, 186 mL of freshly prepared aqueous hydrochloric acid solution was added to a 500 mL three-necked flask, followed by the resulting product (0.14 mol, 31.0 g). The mixture was heated to reflux and the solid was observed to gradually dissolve and become clarified. The reaction was monitored by TLC (unfolding solvent ratio chloroform:methanol:triethylamine = 6:4:1) until the raw material point disappeared completely. Upon completion of the reaction, concentration was carried out under reduced pressure, followed by pulping with the addition of ethyl acetate, at which point a large amount of white solid precipitated. The solids were collected by filtration and the filter cake was washed three times with ethyl acetate and then dried under vacuum to give a white solid crude product. The crude product was further purified by recrystallization with 13.4 g of pure ethyl acetate to finally obtain L-2-aminobutyric acid hydrochloride in a yield of 68.6%, a chemical purity of 99.3% and an ee value of 99.4%.
References
[1] Patent: CN105330557, 2016, A. Location in patent: Paragraph 0063; 0064; 0065
L-2-Aminobutyric acid hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from L-2-Aminobutyric acid hydrochloride manufacturers
- Product
- L-2-Aminobutyric acid hydrochloride 5959-29-5
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 99%min
- Supply Ability
- 500kg
- Release date
- 2021-09-01
- Product
- L-2-Aminobutyric acid hydrochloride 5959-29-5
- Price
- US $7.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- JD 01
- Release date
- 2019-09-15
- Product
- L-2-Aminobutyric acid hydrochloride 5959-29-5
- Price
- US $7.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- JD 01
- Release date
- 2019-09-16