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L-2-Aminobutyric acid hydrochloride

Product Name
L-2-Aminobutyric acid hydrochloride
CAS No.
5959-29-5
Chemical Name
L-2-Aminobutyric acid hydrochloride
Synonyms
AA3;DL-.alph;H-ABU-OH HCL;H-L-2ABU-OH HCL;HoMoalanine HCl;H-2-Abu-OH x HCl;2-ammoniobutyrate;2-ammoniobutanoate;2-azaniumylbutanoate;HOMOALANINE HYDROCHLORIDE
CBNumber
CB8364049
Molecular Formula
C4H10ClNO2
Formula Weight
139.58
MOL File
5959-29-5.mol
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L-2-Aminobutyric acid hydrochloride Property

storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
optical activity
Consistent with structure
CAS DataBase Reference
5959-29-5(CAS DataBase Reference)
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Safety

HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A602935
Product name
(S)-2-AminobutanoicAcidHydrochloride
Packaging
5g
Price
$125
Updated
2021/12/16
Iris Biotech GmbH
Product number
HAA1247
Product name
H-L-2Abu-OH*HCl
Packaging
5G
Price
$135
Updated
2021/12/16
Activate Scientific
Product number
AS49319
Product name
(S)-2-Aminobutanoic acid hydrochloride
Purity
95% ee
Packaging
25g
Price
$247
Updated
2021/12/16
Iris Biotech GmbH
Product number
HAA1247
Product name
H-L-2Abu-OH*HCl
Packaging
25g
Price
$506.25
Updated
2021/12/16
AK Scientific
Product number
J56852
Product name
(S)-2-Aminobutanoicacidhydrochloride
Packaging
1g
Price
$20
Updated
2021/12/16
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L-2-Aminobutyric acid hydrochloride Chemical Properties,Usage,Production

Uses

(S)-2-Aminobutanoic Acid Hydrochloride is an intermediate in the synthesis of Levetiracetam (L331500), which is used as an anticonvulsant.

Synthesis

34047-84-2

5959-29-5

The general procedure for the synthesis of L-2-aminobutyric acid hydrochloride from the compound (CAS: 34047-84-2) was as follows: in step 3, 186 mL of freshly prepared aqueous hydrochloric acid solution was added to a 500 mL three-necked flask, followed by the resulting product (0.14 mol, 31.0 g). The mixture was heated to reflux and the solid was observed to gradually dissolve and become clarified. The reaction was monitored by TLC (unfolding solvent ratio chloroform:methanol:triethylamine = 6:4:1) until the raw material point disappeared completely. Upon completion of the reaction, concentration was carried out under reduced pressure, followed by pulping with the addition of ethyl acetate, at which point a large amount of white solid precipitated. The solids were collected by filtration and the filter cake was washed three times with ethyl acetate and then dried under vacuum to give a white solid crude product. The crude product was further purified by recrystallization with 13.4 g of pure ethyl acetate to finally obtain L-2-aminobutyric acid hydrochloride in a yield of 68.6%, a chemical purity of 99.3% and an ee value of 99.4%.

References

[1] Patent: CN105330557, 2016, A. Location in patent: Paragraph 0063; 0064; 0065

L-2-Aminobutyric acid hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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L-2-Aminobutyric acid hydrochloride Suppliers

Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
ABCR GmbH & CO. KG
Tel
--
Fax
--
Email
info@abcr.de
Country
Germany
ProdList
6831
Advantage
75
IRIS Biotech GmbH
Tel
--
Fax
--
Country
Germany
ProdList
4426
Advantage
68
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View Lastest Price from L-2-Aminobutyric acid hydrochloride manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
L-2-Aminobutyric acid hydrochloride 5959-29-5
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
500kg
Release date
2021-09-01
Career Henan Chemical Co
Product
L-2-Aminobutyric acid hydrochloride 5959-29-5
Price
US $7.00/g
Min. Order
1g
Purity
99%
Supply Ability
JD 01
Release date
2019-09-15
Career Henan Chemical Co
Product
L-2-Aminobutyric acid hydrochloride 5959-29-5
Price
US $7.00/g
Min. Order
1g
Purity
99%
Supply Ability
JD 01
Release date
2019-09-16

5959-29-5, L-2-Aminobutyric acid hydrochlorideRelated Search:


  • H-ABU-OH HCL
  • H-L-2ABU-OH HCL
  • HOMOALANINE HYDROCHLORIDE
  • (S)-2-AMINO-BUTYRIC ACID HYDROCHLORIDE
  • (S)-2-AMINOBUTANOIC ACID HYDROCHLORIDE
  • H-2-Abu-OH x HCl
  • L-2-AMINO-BUTYRIC ACID HYDROCHLORIDE
  • L-2-AMINOBUTYRIC ACID HYDROCHLORIDE SALT
  • S-(+)-2-AminobutyricacidHCl
  • L-2-AMINOBUTYRICACID HYDROCHLORIDE, S-(+)-2-AMINOBUTYRIC ACID HYDROCHLORIDE
  • AA3
  • Butyric acid, 2-amino-, DL- (8CI)
  • DL-.alph
  • Butanoic acid, 2-amino-, hydrochloride (1:1), (2S)-
  • 2-ammoniobutanoate
  • 2-ammoniobutyrate
  • 2-azaniumylbutanoate
  • HoMoalanine HCl
  • L(+)-2-Aminobutyric acid Hydrocloride
  • l(+)-2-aminobutyric acid hcl
  • (S)-2-Aminobutanoic Acid HydrochL
  • Levetiracetam Impurity 34
  • (2S)-2-amino-Butanoic acid hydrochloride (1:1)
  • (2S)-2-Amino-butanoic acid HCl
  • 5959-29-5